The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells
出版年份 2013 全文链接
标题
The mTORC1/mTORC2 inhibitor AZD2014 enhances the radiosensitivity of glioblastoma stem-like cells
作者
关键词
-
出版物
NEURO-ONCOLOGY
Volume 16, Issue 1, Pages 29-37
出版商
Oxford University Press (OUP)
发表日期
2013-12-06
DOI
10.1093/neuonc/not139
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The Brain Microenvironment Preferentially Enhances the Radioresistance of CD133+ Glioblastoma Stem-like Cells
- (2015) Muhammad Jamal et al. NEOPLASIA
- Competitive but Not Allosteric mTOR Kinase Inhibition Enhances Tumor Cell Radiosensitivity
- (2014) Thomas J Hayman et al. Translational Oncology
- Translation Initiation Factor eIF4E Is a Target for Tumor Cell Radiosensitization
- (2012) T. J. Hayman et al. CANCER RESEARCH
- mTOR Signaling in Growth Control and Disease
- (2012) Mathieu Laplante et al. CELL
- The translational landscape of mTOR signalling steers cancer initiation and metastasis
- (2012) Andrew C. Hsieh et al. NATURE
- PI3K and mTOR Signaling Pathways in Cancer: New Data on Targeted Therapies
- (2012) Lise Willems et al. Current Oncology Reports
- γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization
- (2011) Markus Löbrich et al. CELL CYCLE
- Rapamycin passes the torch: a new generation of mTOR inhibitors
- (2011) Don Benjamin et al. NATURE REVIEWS DRUG DISCOVERY
- Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E
- (2010) Andrew C. Hsieh et al. CANCER CELL
- Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2
- (2010) K. Yu et al. CANCER RESEARCH
- Not all substrates are treated equally: Implications for mTOR, rapamycin-resistance, and cancer therapy
- (2010) Andrew Y. Choo et al. CELL CYCLE
- Microenvironmental Regulation of Glioblastoma Radioresponse
- (2010) M. Jamal et al. CLINICAL CANCER RESEARCH
- Targeting Eukaryotic Translation Initiation Factor 4E (eIF4E) in Cancer
- (2010) A. C. Hsieh et al. CLINICAL CANCER RESEARCH
- mTOR signaling in glioblastoma: lessons learned from bench to bedside
- (2010) D. Akhavan et al. NEURO-ONCOLOGY
- AZD8055 Is a Potent, Selective, and Orally Bioavailable ATP-Competitive Mammalian Target of Rapamycin Kinase Inhibitor with In vitro and In vivo Antitumor Activity
- (2009) C. M. Chresta et al. CANCER RESEARCH
- Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
- (2009) Nahum Sonenberg et al. CELL
- SSEA-1 Is an Enrichment Marker for Tumor-Initiating Cells in Human Glioblastoma
- (2009) Myung Jin Son et al. Cell Stem Cell
- CD133+ Glioblastoma Stem-like Cells are Radiosensitive with a Defective DNA Damage Response Compared with Established Cell Lines
- (2009) A. M. McCord et al. CLINICAL CANCER RESEARCH
- An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
- (2009) Carson C. Thoreen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Physiologic Oxygen Concentration Enhances the Stem-Like Properties of CD133+ Human Glioblastoma Cells In vitro
- (2009) A. M. McCord et al. MOLECULAR CANCER RESEARCH
- Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
- (2009) Morris E Feldman et al. PLOS BIOLOGY
- Laminin enhances the growth of human neural stem cells in defined culture media
- (2008) Peter E Hall et al. BMC NEUROSCIENCE
- Radiation-Induced Gene Translation Profiles Reveal Tumor Type and Cancer-Specific Components
- (2008) S. Kumaraswamy et al. CANCER RESEARCH
- Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma
- (2008) Tim F Cloughesy et al. PLOS MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search