In Vivo Analysis of Trypanosoma cruzi Persistence Foci at Single-Cell Resolution

Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection

(2020) Martin C. Taylor et al.   PLoS Neglected Tropical Diseases

Drug-cured experimental Trypanosoma cruzi infections confer long-lasting and cross-strain protection

(2020) Gurdip Singh Mann et al.   PLoS Neglected Tropical Diseases

Low-Level Parasite Persistence Drives Vasculitis and Myositis in Skeletal Muscle of Mice Chronically Infected with Trypanosoma cruzi

(2019) Joseph D. Weaver et al.   INFECTION AND IMMUNITY

Chagas Disease in the United States: a Public Health Approach

(2019) Caryn Bern et al.   CLINICAL MICROBIOLOGY REVIEWS

Assessing the effectiveness of curative benznidazole treatment in preventing chronic cardiac pathology in experimental models of Chagas disease

(2018) Amanda Fortes Francisco et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A novel nanoluciferase-based system to monitor Trypanosoma cruzi infection in mice by bioluminescence imaging

(2018) Erica Silberstein et al.   PLoS One

Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping

(2018) Fernanda Cristina Costa et al.   PLoS Neglected Tropical Diseases

Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure

(2018) Fernando J Sánchez-Valdéz et al.   eLife

Imaging the development of chronic Chagas disease after oral transmission

(2018) Michael D. Lewis et al.   Scientific Reports

Highly competent, non-exhausted CD8+ T cells continue to tightly control pathogen load throughout chronic Trypanosoma cruzi infection

(2018) Angela D. Pack et al.   PLoS Pathogens

An autopsy-based study of Trypanosoma cruzi persistence in organs of chronic chagasic patients and its relevance for transplantation

(2017) Luiz A. Benvenuti et al.   Transplant Infectious Disease

Skin parasite landscape determines host infectiousness in visceral leishmaniasis

(2017) Johannes S. P. Doehl et al.   Nature Communications

4-aminopyridyl-based lead compounds targeting CYP51 prevent spontaneous parasite relapse in a chronic model and improve cardiac pathology in an acute model of Trypanosoma cruzi infection

(2017) Claudia Magalhaes Calvet et al.   PLoS Neglected Tropical Diseases

Chagas disease research and development: Is there light at the end of the tunnel?

(2017) Eric Chatelain   Computational and Structural Biotechnology Journal

Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice

(2016) Sandra Trindade et al.   Cell Host & Microbe

Host and parasite genetics shape a link betweenTrypanosoma cruziinfection dynamics and chronic cardiomyopathy

(2016) Michael D. Lewis et al.   CELLULAR MICROBIOLOGY

Putting Infection Dynamics at the Heart of Chagas Disease

(2016) Michael D. Lewis et al.   TRENDS IN PARASITOLOGY

The Dermis as a Delivery Site of Trypanosoma brucei for Tsetse Flies

(2016) Guy Caljon et al.   PLoS Pathogens

The skin is a significant but overlooked anatomical reservoir for vector-borne African trypanosomes

(2016) Paul Capewell et al.   eLife

Nitroheterocyclic drugs cure experimental Trypanosoma cruzi infections more effectively in the chronic stage than in the acute stage

(2016) Amanda Fortes Francisco et al.   Scientific Reports

Limited Ability of Posaconazole To Cure both Acute and Chronic Trypanosoma cruzi Infections Revealed by Highly SensitiveIn VivoImaging

(2015) Amanda Fortes Francisco et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Current and Future Chemotherapy for Chagas Disease

(2015) Luís Gaspar et al.   CURRENT MEDICINAL CHEMISTRY

Hit and lead criteria in drug discovery for infectious diseases of the developing world

(2015) Kei Katsuno et al.   NATURE REVIEWS DRUG DISCOVERY

Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy

(2015) Carlos A. Morillo et al.   NEW ENGLAND JOURNAL OF MEDICINE

CD8+ T cells in Trypanosoma cruzi infection

(2015) Rick L. Tarleton   Seminars in Immunopathology

Prevalence of Chagas Disease in Latin-American Migrants Living in Europe: A Systematic Review and Meta-analysis

(2015) Ana Requena-Méndez et al.   PLoS Neglected Tropical Diseases

Immunity and immune modulation inTrypanosoma cruziinfection

(2015) Fabíola Cardillo et al.   Pathogens and Disease

Bioluminescence imaging of chronicTrypanosoma cruziinfections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection

(2014) Michael D. Lewis et al.   CELLULAR MICROBIOLOGY

Chagas Disease Cardiomyopathy: Immunopathology and Genetics

(2014) Edecio Cunha-Neto et al.   MEDIATORS OF INFLAMMATION

Randomized Trial of Posaconazole and Benznidazole for Chronic Chagas' Disease

(2014) Israel Molina et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trypanosoma cruzi infection: a review with emphasis on cutaneous manifestations

(2012) Vagish Hemmige et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Reactivation of Chagas’ disease: cutaneous manifestations in two immunosuppressed patients

(2012) Julia Riganti et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Diagnosis and management of Chagas disease and cardiomyopathy

(2012) Antonio L. Ribeiro et al.   Nature Reviews Cardiology

Red-emitting luciferases for bioluminescence reporter and imaging applications

(2009) Bruce R. Branchini et al.   ANALYTICAL BIOCHEMISTRY

Trypanocidal drugs: mechanisms, resistance and new targets

(2009) Shane R. Wilkinson et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Bioluminescent imaging of Trypanosoma cruzi infection

(2008) Kenneth V. Hyland et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY