Regulatory T cells suppress Th17 cell Ca2+ signaling in the spinal cord during murine autoimmune neuroinflammation

Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis

(2019) Hong-Gyun Lee et al.   Nature Communications

Calcium Signaling Controls Pathogenic Th17 Cell-Mediated Inflammation by Regulating Mitochondrial Function

(2019) Ulrike Kaufmann et al.   Cell Metabolism

CRAC Channels And Disease – From Human CRAC Channelopathies And Animal Models To Novel Drugs

(2019) Stefan Feske   CELL CALCIUM

Characterization of leptomeningeal inflammation in rodent experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis

(2019) Suyog Pol et al.   EXPERIMENTAL NEUROLOGY

LFA-1 Controls Th1 and Th17 Motility Behavior in the Inflamed Central Nervous System

(2019) Silvia Dusi et al.   Frontiers in Immunology

The Immunoregulation of Th17 in Host against Intracellular Bacterial Infection

(2018) Yonghong Li et al.   MEDIATORS OF INFLAMMATION

Diversity of innate immune cell subsets across spatial and temporal scales in an EAE mouse model

(2018) Céline Caravagna et al.   Scientific Reports

Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse

(2018) Viveka Mayya et al.   Cell Reports

Regulatory T-cell therapy for autoimmune and autoinflammatory diseases: The next frontier

(2018) Jonathan H. Esensten et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Class II MHC–independent suppressive adhesion of dendritic cells by regulatory T cells in vivo

(2017) Jiacong Yan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Strong adhesion by regulatory T cells induces dendritic cell cytoskeletal polarization and contact-dependent lethargy

(2017) Jiahuan Chen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Visualizing context-dependent calcium signaling in encephalitogenic T cells in vivo by two-photon microscopy

(2017) Nikolaos I. Kyratsous et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T-cell calcium dynamics visualized in a ratiometric tdTomato-GCaMP6f transgenic reporter mouse

(2017) Tobias X Dong et al.   eLife

IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation

(2016) Chih-Chung Lin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autofluorescence multiphoton microscopy for visualization of tissue morphology and cellular dynamics in murine and human airways

(2016) Sarah Kretschmer et al.   LABORATORY INVESTIGATION

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

(2016) Christian Schläger et al.   NATURE

Multifaceted interactions between adaptive immunity and the central nervous system

(2016) J. Kipnis   SCIENCE

Tertiary Lymphoid Organs in Central Nervous System Autoimmunity

(2016) Meike Mitsdoerffer et al.   Frontiers in Immunology

Molecular Biophysics of Orai Store-Operated Ca2+ Channels

(2015) Anna Amcheslavsky et al.   BIOPHYSICAL JOURNAL

Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function

(2015) Ulrike Kaufmann et al.   JOURNAL OF IMMUNOLOGY

Signal strength regulates antigen-mediated T-cell deceleration by distinct mechanisms to promote local exploration or arrest

(2015) Hélène D. Moreau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imaging regulatory T cell dynamics and CTLA4-mediated suppression of T cell priming

(2015) Melanie P. Matheu et al.   Nature Communications

Endogenous Two-Photon Excited Fluorescence Provides Label-Free Visualization of the Inflammatory Response in the Rodent Spinal Cord

(2015) Ortrud Uckermann et al.   Biomed Research International

Dynamic Treg interactions with intratumoral APCs promote local CTL dysfunction

(2014) Christian A. Bauer et al.   JOURNAL OF CLINICAL INVESTIGATION

Two-photon imaging of remyelination of spinal cord axons by engrafted neural precursor cells in a viral model of multiple sclerosis

(2014) M. L. Greenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS

(2014) Michail Koutrolos et al.   Acta Neuropathologica Communications

Fine-Tuning of Regulatory T Cell Function: The Role of Calcium Signals and Naive Regulatory T Cells for Regulatory T Cell Deficiency in Multiple Sclerosis

(2013) A. Schwarz et al.   JOURNAL OF IMMUNOLOGY

Dermal Regulatory T Cells Display Distinct Migratory Behavior That Is Modulated during Adaptive and Innate Inflammation

(2013) Z. Chow et al.   JOURNAL OF IMMUNOLOGY

Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicator

(2013) Marsilius Mues et al.   NATURE MEDICINE

Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier

(2012) Yasunobu Arima et al.   CELL

Dynamic In Situ Cytometry Uncovers T Cell Receptor Signaling during Immunological Synapses and Kinapses In Vivo

(2012) Hélène D. Moreau et al.   IMMUNITY

Toll-like receptor 4-activated B cells out-compete Toll-like receptor 9-activated B cells to establish peripheral immunological tolerance

(2012) M. P. Matheu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS)

(2011) Cris S Constantinescu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Polyclonal Treg cells modulate T effector cell trafficking

(2011) Todd S. Davidson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Th17 Cells Induce Ectopic Lymphoid Follicles in Central Nervous System Tissue Inflammation

(2011) Anneli Peters et al.   IMMUNITY

Fate mapping of IL-17-producing T cells in inflammatory responses

(2011) Keiji Hirota et al.   NATURE IMMUNOLOGY

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Human Regulatory T Cells Rapidly Suppress T Cell Receptor-Induced Ca2+, NF- B, and NFAT Signaling in Conventional T Cells

(2011) A. Schmidt et al.   Science Signaling

In Vivo Imaging of Partially Reversible Th17 Cell-Induced Neuronal Dysfunction in the Course of Encephalomyelitis

(2010) Volker Siffrin et al.   IMMUNITY

Development, regulation and functional capacities of Th17 cells

(2010) Keiji Hirota et al.   Seminars in Immunopathology

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Plasticity of CD4+ T Cell Lineage Differentiation

(2009) Liang Zhou et al.   IMMUNITY

STIMulating store-operated Ca2+ entry

(2009) Michael D. Cahalan   NATURE CELL BIOLOGY

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Localizing central nervous system immune surveillance: Meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis

(2008) Pia Kivisäkk et al.   ANNALS OF NEUROLOGY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

CD44 Mediates Successful Interstitial Navigation by Killer T Cells and Enables Efficient Antitumor Immunity

(2008) Paulus Mrass et al.   IMMUNITY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology