Over-expression of miR-223 induces M2 macrophage through glycolysis alteration and attenuates LPS-induced sepsis mouse model, the cell-based therapy in sepsis

Leaky-gut enhanced lupus progression in the Fc gamma receptor-IIb deficient and pristane-induced mouse models of lupus

(2020) Arthid Thim-uam et al.   Scientific Reports

Modulation of the sigma-1 receptor–IRE1 pathway is beneficial in preclinical models of inflammation and sepsis

(2019) Dorian A. Rosen et al.   Science Translational Medicine

Decreased Protein Kinase C-β Type II Associated with the Prominent Endotoxin Exhaustion in the Macrophage of FcGRIIb−/− Lupus Prone Mice is Revealed by Phosphoproteomic Analysis

(2019) Thunnicha Ondee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Emergence of MicroRNAs as Key Players in Cancer Cell Metabolism

(2019) Sugarniya Subramaniam et al.   CLINICAL CHEMISTRY

Re-education of macrophages as a therapeutic strategy in cancer

(2019) Joanna Kowal et al.   Immunotherapy

MicroRNAs as Molecular Switches in Macrophage Activation

(2019) Graziella Curtale et al.   Frontiers in Immunology

Lipocalin-2 (Lcn-2) Attenuates Polymicrobial Sepsis with LPS Preconditioning (LPS Tolerance) in FcGRIIb Deficient Lupus Mice

(2019) Thunnicha Ondee et al.   Cells

Altered expression of microRNA-223 in the plasma of patients with first-episode schizophrenia and its possible relation to neuronal migration-related genes

(2019) Zhilei Zhao et al.   Translational Psychiatry

Regulation of macrophage immunometabolism in atherosclerosis

(2018) Graeme J. Koelwyn et al.   NATURE IMMUNOLOGY

HIF1α-dependent glycolysis promotes macrophage functional activities in protecting against bacterial and fungal infection

(2018) Chunxiao Li et al.   Scientific Reports

Metabolic Stress in the Immune Function of T Cells, Macrophages and Dendritic Cells

(2018) Charlotte Domblides et al.   Cells

Gold nanoparticles attenuates bacterial sepsis in cecal ligation and puncture mouse model through the induction of M2 macrophage polarization

(2018) Sujittra Taratummarat et al.   BMC MICROBIOLOGY

Glycolytic Stimulation Is Not a Requirement for M2 Macrophage Differentiation

(2018) Feilong Wang et al.   Cell Metabolism

Regulation of microRNA function in animals

(2018) Luca F. R. Gebert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

HIF1α-Induced Glycolysis Metabolism Is Essential to the Activation of Inflammatory Macrophages

(2017) Ting Wang et al.   MEDIATORS OF INFLAMMATION

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Transcriptomic profiling in human mesangial cells using patient-derived lupus autoantibodies identified miR-10a as a potential regulator of IL8

(2017) Pattarin Tangtanatakul et al.   Scientific Reports

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation

(2016) Stanley Ching-Cheng Huang et al.   IMMUNITY

Emerging role of microRNAs in regulating macrophage activation and polarization in immune response and inflammation

(2016) Xiao-qin Wu et al.   IMMUNOLOGY

MiR-146a modulates macrophage polarization by inhibiting Notch1 pathway in RAW264.7 macrophages

(2016) Cheng Huang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Overexpression of miR-223 Tips the Balance of Pro- and Anti-hypertrophic Signaling Cascades toward Physiologic Cardiac Hypertrophy

(2016) Liwang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF1α and metabolic reprogramming in inflammation

(2016) Sarah E. Corcoran et al.   JOURNAL OF CLINICAL INVESTIGATION

MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response

(2016) Kobina Essandoh et al.   SHOCK

Gastrointestinal Leakage Detected by Serum (1→3)-β-D-Glucan in Mouse Models and a Pilot Study in Patients with Sepsis

(2016) Asada Leelahavanichkul et al.   SHOCK

Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

(2016) Anthony J Covarrubias et al.   eLife

Sepsis and septic shock

(2016) Richard S. Hotchkiss et al.   Nature Reviews Disease Primers

MicroRNA-223 Induced Repolarization of Peritoneal Macrophages Using CD44 Targeting Hyaluronic Acid Nanoparticles for Anti-Inflammatory Effects

(2016) Thanh-Huyen Tran et al.   PLoS One

High-dose ascorbate with low-dose amphotericin B attenuates severity of disease in a model of the reappearance of candidemia during sepsis in the mouse

(2015) Asada Leelahavanichkul et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Macrophages: Development and Tissue Specialization

(2015) Chen Varol et al.   Annual Review of Immunology

MicroRNA-223 is a crucial mediator of PPARγ-regulated alternative macrophage activation

(2015) Wei Ying et al.   JOURNAL OF CLINICAL INVESTIGATION

MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis

(2015) Mireille Ouimet et al.   JOURNAL OF CLINICAL INVESTIGATION

Pyruvate Dehydrogenase Kinase 1 Participates in Macrophage Polarization via Regulating Glucose Metabolism

(2015) Zheng Tan et al.   JOURNAL OF IMMUNOLOGY

Attenuation of Cardiac Dysfunction in Polymicrobial Sepsis by MicroRNA-146a Is Mediated via Targeting of IRAK1 and TRAF6 Expression

(2015) Ming Gao et al.   JOURNAL OF IMMUNOLOGY

The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling

(2015) Bryan D. Fleming et al.   JOURNAL OF LEUKOCYTE BIOLOGY

miRWalk2.0: a comprehensive atlas of microRNA-target interactions

(2015) Harsh Dweep et al.   NATURE METHODS

Review of aerobic glycolysis and its key enzymes - new targets for lung cancer therapy

(2015) Xue-bing Li et al.   Thoracic Cancer

Akt2 Deficiency Protects from Acute Lung Injury via Alternative Macrophage Activation and miR-146a Induction in Mice

(2013) E. Vergadi et al.   JOURNAL OF IMMUNOLOGY

Dissociation of Endotoxin Tolerance and Differentiation of Alternatively Activated Macrophages

(2013) R. Rajaiah et al.   JOURNAL OF IMMUNOLOGY

Interplay of macrophages and T cells in the lung vasculature

(2012) Evgenia Gerasimovskaya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Human umbilical cord mesenchymal stem cells reduce systemic inflammation and attenuate LPS-induced acute lung injury in rats

(2012) Jianjun Li et al.   Journal of Inflammation-London

Inducible MicroRNA-223 Down-Regulation Promotes TLR-Triggered IL-6 and IL-1β Production in Macrophages by Targeting STAT3

(2012) Qingyun Chen et al.   PLoS One

Loss of Inducible Nitric Oxide Synthase Expression in the Mouse Renal Cell Carcinoma Cell Line RENCA Is Mediated by MicroRNA miR-146a

(2010) Christina Perske et al.   AMERICAN JOURNAL OF PATHOLOGY

Serum miR-146a and miR-223 as potential new biomarkers for sepsis

(2010) Jia-feng Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of a Metabolic Gene Regulatory Network Downstream of mTOR Complex 1

(2010) Katrin Düvel et al.   MOLECULAR CELL

Animal models of sepsis and sepsis-induced kidney injury

(2009) Kent Doi et al.   JOURNAL OF CLINICAL INVESTIGATION

LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manner

(2008) Kenichiro Nishi et al.   ANTIOXIDANTS & REDOX SIGNALING

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE