Review
Chemistry, Medicinal
Dioni Arrieche, Jaime R. Cabrera-Pardo, Aurelio San-Martin, Hector Carrasco, Lautaro Taborga
Summary: This review summarizes the fungal natural products isolated from Antarctic and Chilean marine environments and their biological activities.
Review
Chemistry, Medicinal
Zhaoming Liu, Mingqiong Li, Shuo Wang, Huibin Huang, Weimin Zhang
Summary: This review summarizes the chemical structures and biological activities of 89 new fungal-derived sulfur-containing metabolites discovered from marine and terrestrial fungi. The review also briefly discusses the preliminary mechanism for C-S bond formation in fungi.
Article
Food Science & Technology
Maria Rosa de Moraes, Tayse Ferreira Ferreira da Silveira, Janclei Pereira Coutinho, Danilo Santos Souza, Marta Cristina Teixeira Duarte, Renata Teixeira Duarte, Jose Teixeira Filho, Helena Teixeira Godoy
Summary: Atemoya fruit contains rich phenolic compounds, with the highest levels found in the peels, showing strong antioxidant and antimicrobial activities. The seed oil is rich in alpha-tocopherol and gamma-tocopherol, along with significant amounts of unsaturated fatty acids such as monounsaturated and polyunsaturated fats.
Review
Biochemistry & Molecular Biology
Honghua Li, Yanqi Fu, Fuhang Song, Xiuli Xu
Summary: This review summarizes 72 compounds isolated from marine-derived Penicillium fungi and their antimicrobial activities from 2020 to 2023. These compounds can be categorized into terpenoids, polyketides, alkaloids, and other structural compounds, with terpenoids and polyketides being the most abundant. Some of these compounds exhibit potent inhibitory effects against various pathogenic bacteria and fungi. The aim of this review is to provide valuable information and insights for the efficient utilization of Penicillium spp. and their secondary metabolites.
CHEMISTRY & BIODIVERSITY
(2023)
Article
Microbiology
Sonia Coutinho, Vanessa Matos, Natalia Seixas, Hellen Rodrigues, Vanessa B. Paula, Lais Freitas, Teresa Dias, Francisco de Assis Ribeiro Santos, Luis G. Dias, Leticia M. Estevinho
Summary: This study investigated the botanical origin, physicochemical profile, and biological activities of geopropolis from M. scutellaris collected during rainy and dry seasons. The results showed that rainy-season geopropolis had higher phenol and flavonoid content and exhibited superior antioxidant, antimicrobial, and anti-inflammatory activities compared to dry-season geopropolis.
Review
Environmental Sciences
Peishan Li, Hongmei Lu, Yanzhu Zhang, Xuejiao Zhang, Lianliang Liu, Min Wang, Liwei Liu
Summary: This paper systematically discusses 140 compounds produced by sponge-associated microorganisms from 2017 to 2022 in terms of their structures, biological activities, strain sources, and mining strategies, which not only further updates the natural product library of sponge-associated microorganisms but also provides a new guideline for exploring the dark matter in sponges.
FRONTIERS IN MARINE SCIENCE
(2023)
Review
Biochemistry & Molecular Biology
Haoyi Sun, Kangping Sun, Jingyong Sun
Summary: The ocean is an important source of natural products, and in recent years, researchers have made significant progress in the fields of separation and extraction, derivative synthesis, structural studies, and biological evaluation of marine natural products. This review focuses on marine indole natural products with good pharmacological activity and research value, including monomeric indoles, indole peptides, bis-indoles, and annelated indoles. Most of these compounds exhibit cytotoxic, antiviral, antifungal, or anti-inflammatory activities.
Article
Biochemistry & Molecular Biology
Tomasz Tronina, Mateusz Luzny, Monika Dymarska, Monika Urbaniak, Ewa Kozlowska, Michal Piegza, Lukasz Stepien, Tomasz Janeczko
Summary: Quercetin, the most abundant flavonoid in food products, has various biological activities and is used for medical applications. However, its low water solubility may limit its therapeutic potential.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Diana Pereira, Tiago Soares Carreira, Nuno Alves, Angela Sousa, Joana F. A. Valente
Summary: The global COVID-19 pandemic has raised awareness of the risk posed by microorganisms to human well-being and survival. Scientists worldwide are actively searching for solutions to kill or slow down the spread of the virus. Metals have been extensively studied as antimicrobial solutions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Chemistry, Multidisciplinary
Kwang-Yoon Ko, Zoe E. Wilson, Margaret A. Brimble
Summary: Researchers have synthesized and established the absolute stereochemistry of Callyspongiolide, a macrolide natural product with promising caspase-independent bioactivity, contributing to the wider field of macrolide synthesis.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Article
Plant Sciences
Mohamed R. Habib, Ahmed A. Hamed, Rasha E. M. Ali, Khaled M. Zayed, Rasha M. Gad El-Karim, Rehab Sabour, Hanaa M. Abu El-Einin, Mosad A. Ghareeb
Summary: This study investigated the chemical profile and biological activities of tissue extracts from Thais savignyi. The ethyl acetate extract showed the highest antioxidant capacity, antibacterial, antibiofilm, antifungal, and cytotoxic activities.
PHARMACEUTICAL BIOLOGY
(2022)
Review
Food Science & Technology
Md. Ashraf Hussain, Tofael Ahmed Sumon, Sabuj Kanti Mazumder, Mir Mohammad Ali, Won Je Jang, Muyassar Hamid Abualreesh, S. M. Sharifuzzaman, Christopher Lyon Brown, Hyun-Tai Lee, Eun-Woo Lee, Md. Tawheed Hasan
Summary: Meeting consumer demands for fresh and safely processed fisheries products free of chemical preservatives is a challenge for the aqua-food industry. Natural preservatives like chitosan and essential oils have antimicrobial and antioxidant properties that can extend shelf-life and maintain quality of fish and seafood products. This study highlights recent developments and effective use of natural preservatives in the aqua-food industry, while addressing the harmful impacts of chemical preservatives and noting research gaps in Southeast Asian countries.
Review
Marine & Freshwater Biology
Li-Li Hong, Ya-Fang Ding, Wei Zhang, Hou-Wen Lin
Summary: Marine sponges are important sources of bioactive compounds, with over 200 new compounds being isolated each year and contributing to 23% of approved marine drugs. This review provides a statistical analysis, structural diversity, and pharmacological activity of sponge-derived natural products from 2009 to 2018. The compounds show a range of biological activities, including cytotoxic, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, enzyme inhibition, and antimalarial activities.
MARINE LIFE SCIENCE & TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jose X. Soares, Ines Afonso, Adaleta Omerbasic, Daniela R. P. Loureiro, Madalena M. M. Pinto, Carlos M. M. Afonso
Summary: The emergence of multiresistant bacteria and shortage of antibacterials drives the search for novel agents. Marine natural products, specifically polyketides, have shown promising antibacterial activity. This study identified a dataset of 246 marine polyketides and characterized their chemical space and molecular similarity.
Article
Biochemistry & Molecular Biology
Simon Vlad Luca, Krystyna Skalicka-Wozniak, Cosmin-Teodor Mihai, Adina Catinca Gradinaru, Alexandru Mandici, Nina Ciocarlan, Anca Miron, Ana Clara Aprotosoaie
Summary: This study evaluated the phytochemical profile and potential antimicrobial, antioxidant, and cytotoxic activities of ten Salvia species from Eastern Europe. The results showed that S. officinalis exhibited the highest antimicrobial and antioxidant activities, but no significant cytotoxic effect on human breast carcinoma cells.
