期刊
PHYTOCHEMISTRY REVIEWS
卷 20, 期 1, 页码 325-342出版社
SPRINGER
DOI: 10.1007/s11101-020-09685-6
关键词
Fatty acids; Acetogenins; Lembehynes; Z-Double bonds; Biological activity
资金
- Russian Science Foundation [18-73-10030]
- Russian Foundation for Basic Research [18-29-09068, 19-03-00603, 18-33-20058]
- IPC RAS State Registration [AAAA-A19-119022290007-9, AAAA-A19-119022290008-6]
- Russian Ministry of Education and Science [2019-05-595-000-058]
- Russian Science Foundation [18-73-10030] Funding Source: Russian Science Foundation
The review provides a summary of natural compounds containing bis-methylene-interrupted Z-double bonds, their synthesis approaches, and biological activities. It is of interest to researchers in the fields of organic, medicinal, phyto- and biochemistry, pharmacology, and pharmacognosy, offering insights into stereoselective formation, biological activities, total synthesis, and occurrence of these compounds in various organisms.
The review summarizes data on natural compounds including higher carboxylic acids, acetogenins, lembehynes, and insect pheromones containing bis-methylene-interrupted Z-double bonds in the molecules, general approaches to their synthesis, and the biological activities they exhibit. The review is of interest for a wide circle of researchers in the field of organic, medicinal, phyto- and biochemistry, and pharmacology, and pharmacognosy, as it describes the key strategies of stereoselective formation of bis-methylene-interrupted Z-double bonds, known biological activities of these natural compounds, their total synthesis, and occurrence in plants, animals, and microorganisms.
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