Short-Chain Fatty Acids Ameliorate Diabetic Nephropathy via GPR43-Mediated Inhibition of Oxidative Stress and NF-κB Signaling

Tangeretin inhibits high glucose-induced extracellular matrix accumulation in human glomerular mesangial cells

(2018) Fang Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

Dietary fibre intake in relation to the risk of incident chronic kidney disease

(2018) Parvin Mirmiran et al.   BRITISH JOURNAL OF NUTRITION

The Gut Microbiome as a Target for the Treatment of Type 2 Diabetes

(2018) Ömrüm Aydin et al.   Current Diabetes Reports

Pro- and anti-inflammatory effects of short chain fatty acids on immune and endothelial cells

(2018) Meng Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

FFAR2-FFAR3 receptor heteromerization modulates short-chain fatty acid sensing

(2018) Zhiwei Ang et al.   FASEB JOURNAL

Sodium butyrate supplementation ameliorates diabetic inflammation in db/db mice

(2018) Youhua Xu et al.   JOURNAL OF ENDOCRINOLOGY

Catalytic activation of β-arrestin by GPCRs

(2018) Kelsie Eichel et al.   NATURE

Gut microbiome may contribute to insulin resistance and systemic inflammation in obese rodents: a meta-analysis

(2018) Na Jiao et al.   PHYSIOLOGICAL GENOMICS

Human milk oligosaccharides protect against the development of autoimmune diabetes in NOD-mice

(2018) Ling Xiao et al.   Scientific Reports

Probiotic Species in the Modulation of Gut Microbiota: An Overview

(2018) Md. Abul Kalam Azad et al.   Biomed Research International

Short-Chain Fatty Acids Inhibit Oxidative Stress and Inflammation in Mesangial Cells Induced by High Glucose and Lipopolysaccharide

(2017) Wei Huang et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

The role of short-chain fatty acids in kidney injury induced by gut-derived inflammatory response

(2017) Wei Huang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Gut microbiota as a potential target of metabolic syndrome: the role of probiotics and prebiotics

(2017) Mingqian He et al.   Cell and Bioscience

The Immune System Bridges the Gut Microbiota with Systemic Energy Homeostasis: Focus on TLRs, Mucosal Barrier, and SCFAs

(2017) Martina Spiljar et al.   Frontiers in Immunology

The dual role of short fatty acid chains in the pathogenesis of autoimmune disease models

(2017) Miho Mizuno et al.   PLoS One

A reduction in the butyrate producing species Roseburia spp. and Faecalibacterium prausnitzii is associated with chronic kidney disease progression

(2016) Shuanghong Jiang et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Sodium butyrate activates NRF2 to ameliorate diabetic nephropathy possibly via inhibition of HDAC

(2016) Wenpeng Dong et al.   JOURNAL OF ENDOCRINOLOGY

Chronically Elevated Levels of Short-Chain Fatty Acids Induce T Cell-Mediated Ureteritis and Hydronephrosis

(2016) J. Park et al.   JOURNAL OF IMMUNOLOGY

Short- and medium-chain fatty acids in energy metabolism: the cellular perspective

(2016) Peter Schönfeld et al.   JOURNAL OF LIPID RESEARCH

Benefits of short-chain fatty acids and their receptors in inflammation and carcinogenesis

(2016) Sathish Sivaprakasam et al.   PHARMACOLOGY & THERAPEUTICS

Exosomes from high glucose-treated glomerular endothelial cells activate mesangial cells to promote renal fibrosis

(2016) Xiao-ming Wu et al.   Biology Open

Short Chain Fatty Acids Prevent High-fat-diet-induced Obesity in Mice by Regulating G Protein-coupled Receptors and Gut Microbiota

(2016) Yuanyuan Lu et al.   Scientific Reports

The short-chain fatty acid receptor, FFA2, contributes to gestational glucose homeostasis

(2015) Miles Fuller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

SCFAs Take a Toll En Route to Metabolic Syndrome

(2015) André Marette et al.   Cell Metabolism

Selective FFA2 Agonism Appears to Act via Intestinal PYY to Reduce Transit and Food Intake but Does Not Improve Glucose Tolerance in Mouse Models

(2015) Sarah Forbes et al.   DIABETES

Polyploidy Analysis and Attenuation of Oxidative Stress in Hepatic Tissue of STZ-Induced Diabetic Rats Treated with an Aqueous Extract ofVochysia rufa

(2015) Izabela Barbosa Moraes et al.   Evidence-based Complementary and Alternative Medicine

The role of short chain fatty acids in appetite regulation and energy homeostasis

(2015) C S Byrne et al.   INTERNATIONAL JOURNAL OF OBESITY

Gut Bacteria Products Prevent AKI Induced by Ischemia-Reperfusion

(2015) V. Andrade-Oliveira et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Redirection of Epithelial Immune Responses by Short-Chain Fatty Acids through Inhibition of Histone Deacetylases

(2015) May Young Lin et al.   Frontiers in Immunology

Sodium butyrate, a HDAC inhibitor ameliorates eNOS, iNOS and TGF-β1-induced fibrogenesis, apoptosis and DNA damage in the kidney of juvenile diabetic rats

(2014) Sabbir Khan et al.   FOOD AND CHEMICAL TOXICOLOGY

β-Arrestin 2 Mediates G Protein-Coupled Receptor 43 Signals to Nuclear Factor-κB

(2013) Su Ui Lee et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Identification and characterization of the free fatty acid receptor 2 (FFA2) and a novel functional FFA2-like receptor (FFA2L) for short-chain fatty acids in pigs: Evidence for the existence of a duplicated FFA2 gene (FFA2L) in some mammalian species

(2013) J. Zhang et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Histone deacetylase inhibitor, sodium butyrate, attenuates gentamicin-induced nephrotoxicity by increasing prohibitin protein expression in rats

(2013) Xuefeng Sun et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Short-Chain Fatty Acids Suppress Lipopolysaccharide-Induced Production of Nitric Oxide and Proinflammatory Cytokines Through Inhibition of NF-κB Pathway in RAW264.7 Cells

(2012) Tengfei Liu et al.   INFLAMMATION

Sodium butyrate decreases the activation of NF- B reducing inflammation and oxidative damage in the kidney of rats subjected to contrast-induced nephropathy

(2012) R. A. Machado et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION