Melatonin Alleviates Neuroinflammation and Metabolic Disorder in DSS-Induced Depression Rats

The gut microbiome regulates the increases in depressive-type behaviors and in inflammatory processes in the ventral hippocampus of stress vulnerable rats

(2019) Jiah Pearson-Leary et al.   MOLECULAR PSYCHIATRY

Protein tyrosine phosphatase non-receptor type 22 modulates colitis in a microbiota-dependent manner

(2019) Marianne R. Spalinger et al.   JOURNAL OF CLINICAL INVESTIGATION

Role of melatonin in sleep deprivation‐induced intestinal barrier dysfunction in mice

(2019) Ting Gao et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Alleviates Cognition Impairment by Antagonizing Brain Insulin Resistance in Aged Rats Fed a High‐Fat Diet

(2019) Jiqu Xu et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Attenuates LPS-Induced Acute Depressive-Like Behaviors and Microglial NLRP3 Inflammasome Activation Through the SIRT1/Nrf2 Pathway

(2019) Burak I. Arioz et al.   Frontiers in Immunology

Melatonin safeguards against fatty liver by antagonizing TRAFs‐mediated ASK1 deubiquitination and stabilization in a β‐arrestin‐1 dependent manner

(2019) Dong‐Jie Li et al.   JOURNAL OF PINEAL RESEARCH

The influence of the brain–gut axis in inflammatory bowel disease and possible implications for treatment

(2019) David J Gracie et al.   Lancet Gastroenterology & Hepatology

Malva sylvestris extract alleviates the astrogliosis and inflammatory stress in LPS-induced depression mice

(2019) Ye Wu et al.   JOURNAL OF NEUROIMMUNOLOGY

The Gut Microbiome Modulates the Changes in Liver Metabolism and in Inflammatory Processes in the Brain of Chronic Unpredictable Mild Stress Rats

(2019) Wei-jie Lv et al.   Oxidative Medicine and Cellular Longevity

Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism

(2019) Fengjie Huang et al.   Nature Communications

Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson’s disease mice: Gut microbiota, glial reaction and TLR4/TNF-α signaling pathway

(2018) Meng-Fei Sun et al.   BRAIN BEHAVIOR AND IMMUNITY

Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice

(2018) F. Guida et al.   BRAIN BEHAVIOR AND IMMUNITY

Bi-directionality of Brain–Gut Interactions in Patients With Inflammatory Bowel Disease

(2018) David J. Gracie et al.   GASTROENTEROLOGY

Gut microbiota modulate neurobehavior through changes in brain insulin sensitivity and metabolism

(2018) Marion Soto et al.   MOLECULAR PSYCHIATRY

Metabolite identification in fecal microbiota transplantation mouse livers and combined proteomics with chronic unpredictive mild stress mouse livers

(2018) Bo Li et al.   Translational Psychiatry

Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier

(2018) Lesley Hoyles et al.   Microbiome

Clostridium butyricum Attenuates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behavior in Mice via the Gut-Brain Axis

(2018) Jing Sun et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Melatonin reprogramming of gut microbiota improves lipid dysmetabolism in high fat diet-fed mice

(2018) Jie Yin et al.   JOURNAL OF PINEAL RESEARCH

Dual-specificity Phosphatase 26 Protects Against Nonalcoholic Fatty Liver Disease in Mice through TAK1 Suppression

(2018) Ping Ye et al.   HEPATOLOGY

The Systemic Inflammatory Response to Clostridium Difficile Infection (CDI) in Patients with Ulcerative Colitis

(2017) Julajak Limsrivilai et al.   GASTROENTEROLOGY

Increased human intestinal barrier permeability plasma biomarkers zonulin and FABP2 correlated with plasma LPS and altered gut microbiome in anxiety or depression

(2017) Bruce R Stevens et al.   GUT

Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota

(2017) Wenkai Ren et al.   JOURNAL OF PINEAL RESEARCH

Melatonin alleviates cadmium-induced liver injury by inhibiting the TXNIP-NLRP3 inflammasome

(2017) Zhengwang Cao et al.   JOURNAL OF PINEAL RESEARCH

Melatonin protects against lipid-induced mitochondrial dysfunction in hepatocytes and inhibits stellate cell activation during hepatic fibrosis in mice

(2017) Nabanita Das et al.   JOURNAL OF PINEAL RESEARCH

Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function

(2017) Miguel Mendivil-Perez et al.   JOURNAL OF PINEAL RESEARCH

Melatonin prevents obesity through modulation of gut microbiota in mice

(2017) Pengfei Xu et al.   JOURNAL OF PINEAL RESEARCH

The deubiquitinating enzyme TNFAIP3 mediates inactivation of hepatic ASK1 and ameliorates nonalcoholic steatohepatitis

(2017) Peng Zhang et al.   NATURE MEDICINE

Interactions between the microbiota, immune and nervous systems in health and disease

(2017) Thomas C Fung et al.   NATURE NEUROSCIENCE

Magnitude and sources of distress in mid-life adults with chronic medical illness: an exploratory mixed-methods analysis

(2017) Elizabeth N. Madva et al.   Psychology Health & Medicine

Evidence that independent gut-to-brain and brain-to-gut pathways operate in the irritable bowel syndrome and functional dyspepsia: a 1-year population-based prospective study

(2016) N. A. Koloski et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Characterization of the anti-inflammatory Lactobacillus reuteri BM36301 and its probiotic benefits on aged mice

(2016) Joon Lee et al.   BMC MICROBIOLOGY

Lactobacillus acidophilus alleviates the inflammatory response to enterotoxigenic Escherichia coli K88 via inhibition of the NF-κB and p38 mitogen-activated protein kinase signaling pathways in piglets

(2016) Haihua Li et al.   BMC MICROBIOLOGY

From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites

(2016) Ara Koh et al.   CELL

Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation

(2016) Lirui Wang et al.   Cell Host & Microbe

Microbiota-induced obesity requires farnesoid X receptor

(2016) Ava Parséus et al.   GUT

Targeting hepatic TRAF1-ASK1 signaling to improve inflammation, insulin resistance, and hepatic steatosis

(2016) Mei Xiang et al.   JOURNAL OF HEPATOLOGY

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Depression and anxiety in patients with Inflammatory Bowel Disease: A systematic review

(2016) Rachel Neuendorf et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Inflammasome signaling affects anxiety- and depressive-like behavior and gut microbiome composition

(2016) M-L Wong et al.   MOLECULAR PSYCHIATRY

Q&A: Eva Szigethy

(2016) Neil Savage   NATURE

Butyrate, neuroepigenetics and the gut microbiome: Can a high fiber diet improve brain health?

(2016) Megan W. Bourassa et al.   NEUROSCIENCE LETTERS

The maternal microbiota drives early postnatal innate immune development

(2016) M. Gomez de Aguero et al.   SCIENCE

Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome

(2016) Robert P. Dickson et al.   Nature Microbiology

Hepatic Macrosteatosis Is Partially Converted to Microsteatosis by Melatonin Supplementation in ob/ob Mice Non-Alcoholic Fatty Liver Disease

(2016) Alessandra Stacchiotti et al.   PLoS One

Colonic luminal microbiota and bacterial metabolite composition in pregnant Huanjiang mini-pigs: effects of food composition at different times of pregnancy

(2016) Xiang-feng Kong et al.   Scientific Reports

Anti-inflammatory potential of probiotic Lactobacillus spp. on carrageenan induced paw edema in Wistar rats

(2015) Ann Catherine Archer et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Compact graphical representation of phylogenetic data and metadata with GraPhlAn

(2015) Francesco Asnicar et al.   PeerJ

The incidence and risk factors for developing depression after being diagnosed with inflammatory bowel disease: a cohort study

(2014) A. J. Panara et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Melatonin and the circadian system: contributions to successful female reproduction

(2014) Russel J. Reiter et al.   FERTILITY AND STERILITY

Major depression and suicide attempts in patients with liver disease in the United States

(2014) Yann Le Strat et al.   LIVER INTERNATIONAL

Melatonin: Exceeding Expectations

(2014) Russel J. Reiter et al.   PHYSIOLOGY

The Liver May Act as a Firewall Mediating Mutualism Between the Host and Its Gut Commensal Microbiota

(2014) M. L. Balmer et al.   Science Translational Medicine

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

Bile acids are nutrient signaling hormones

(2014) Huiping Zhou et al.   STEROIDS

Expression of Zonulin, c-kit, and Glial Fibrillary Acidic Protein in Human Gliomas

(2014) Marco Skardelly et al.   Translational Oncology

Application of high-throughput sequencing in understanding human oral microbiome related with health and disease

(2014) Hui Chen et al.   Frontiers in Microbiology

Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences

(2013) Morgan G I Langille et al.   NATURE BIOTECHNOLOGY

Transmigration of Neural Stem Cells across the Blood Brain Barrier Induced by Glioma Cells

(2013) Mónica Díaz-Coránguez et al.   PLoS One

Why the dim light melatonin onset (DLMO) should be measured before treatment of patients with circadian rhythm sleep disorders

(2013) Henry Keijzer et al.   SLEEP MEDICINE REVIEWS

The brain–gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study

(2012) N A Koloski et al.   GUT

Mood disorders in inflammatory bowel disease: Relation to diagnosis, disease activity, perceived stress, and other factors

(2012) J. R. Goodhand et al.   INFLAMMATORY BOWEL DISEASES

Enhancement of Dorsal Hippocampal Activity by Knockdown of HCN1 Channels Leads to Anxiolytic- and Antidepressant-like Behaviors

(2012) Chung Sub Kim et al.   NEURON

Polymorphism of the TLR4 Gene Reduces the Risk of Hepatitis C Virus-Induced Hepatocellular Carcinoma

(2012) José A. Agúndez et al.   ONCOLOGY

Psychological Issues in Inflammatory Bowel Disease: An Overview

(2012) M. S. Sajadinejad et al.   Gastroenterology Research and Practice

FLASH: fast length adjustment of short reads to improve genome assemblies

(2011) T. Magoc et al.   BIOINFORMATICS

Integrative analysis of environmental sequences using MEGAN4

(2011) D. H. Huson et al.   GENOME RESEARCH

Characterization of fecal microbial communities in patients with liver cirrhosis

(2011) Yanfei Chen et al.   HEPATOLOGY

Distance-based multivariate analyses confound location and dispersion effects

(2011) David I. Warton et al.   Methods in Ecology and Evolution

Metagenomic biomarker discovery and explanation

(2011) Nicola Segata et al.   GENOME BIOLOGY

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Stress Coping, Distress and Health Perceptions in Inflammatory Bowel Disease and Community Controls

(2009) Lesley A Graff et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Defining the healthy "core microbiome" of oral microbial communities

(2009) Egija Zaura et al.   BMC MICROBIOLOGY

Statistical Methods for Detecting Differentially Abundant Features in Clinical Metagenomic Samples

(2009) James Robert White et al.   PLoS Computational Biology

Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of toll-like receptor 4 to hepatic stellate cell responses

(2008) Jinsheng Guo et al.   HEPATOLOGY

Longitudinal study of quality of life and psychological functioning for active, fluctuating, and inactive disease patterns in inflammatory bowel disease

(2008) Lisa M. Lix et al.   INFLAMMATORY BOWEL DISEASES

Reconsidering the methodology of “stress” research in inflammatory bowel disease

(2008) Laurie Keefer et al.   Journal of Crohns & Colitis