Inflammation suppression by dexamethasone via inhibition of CD147-mediated NF-κB pathway in collagen-induced arthritis rats

Syndecan‐4 involves in the pathogenesis of rheumatoid arthritis by regulating the inflammatory response and apoptosis of fibroblast‐like synoviocytes

(2019) Peian Cai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Kirenol Inhibits the Function and Inflammation of Fibroblast-like Synoviocytes in Rheumatoid Arthritis in vitro and in vivo

(2019) Jing Wu et al.   Frontiers in Immunology

Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis

(2018) Mascha Koenen et al.   ANNALS OF THE RHEUMATIC DISEASES

Oxidative stress, consequences and ROS mediated cellular signaling in rheumatoid arthritis

(2018) Abdul-Rehman Phull et al.   CHEMICO-BIOLOGICAL INTERACTIONS

α-Mangostin, A Natural Xanthone, Induces Apoptosis and ROS Accumulation in Human Rheumatoid Fibroblast-Like Synoviocyte MH7A Cells

(2018) J. Zhang et al.   CURRENT MOLECULAR MEDICINE

Neutrophils and redox stress in the pathogenesis of autoimmune disease

(2018) Laurence Glennon-Alty et al.   FREE RADICAL BIOLOGY AND MEDICINE

A novel dexamethasone-loaded liposome alleviates rheumatoid arthritis in rats

(2018) Mengdi Jia et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Salicin from Alangium chinense Ameliorates Rheumatoid Arthritis by Modulating the Nrf2-HO-1-ROS Pathways

(2018) Ke-feng Zhai et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anti-inflammatory and anti-arthritic effects of the ethanolic extract of Aralia continentalis Kitag. in IL-1β-stimulated human fibroblast-like synoviocytes and rodent models of polyarthritis and nociception

(2018) Riwon Hong et al.   PHYTOMEDICINE

Time dependent neuroprotection of dexamethasone in experimental focal cerebral ischemia: The involvement of NF-κB pathways

(2018) Wen-Hao Sun et al.   BRAIN RESEARCH

Aspirin promotes apoptosis and inhibits proliferation by blocking G0/G1 into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NF-κB signaling pathway

(2018) Xiaoqi Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Modeling Sex Differences in Anti-inflammatory Effects of Dexamethasone in Arthritic Rats

(2018) Dawei Song et al.   PHARMACEUTICAL RESEARCH

Lipopolysaccharide (LPS) enhances prostate cancer metastasis potentially through NF-κB activation and recurrent dexamethasone administration fails to suppress it in vivo

(2018) Sumeet Jain et al.   PROSTATE

Resveratrol Alleviates Rheumatoid Arthritis via Reducing ROS and Inflammation, Inhibiting MAPK Signaling Pathways, and Suppressing Angiogenesis

(2018) Guliang Yang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

CD147 promotes progression of head and neck squamous cell carcinoma via NF-kappa B signaling

(2018) Binbin Yu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Dihydromyricetin Inhibits Inflammation of Fibroblast-Like Synoviocytes through Regulation of Nuclear Factor-κB Signaling in Rats with Collagen-Induced Arthritis

(2018) Jing Wu et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Reactive Oxygen Species from NADPH Oxidase and Mitochondria Participate in the Proliferation of Aortic Smooth Muscle Cells from a Model of Metabolic Syndrome

(2018) Ocarol López-Acosta et al.   Oxidative Medicine and Cellular Longevity

Piperlongumine inhibits the proliferation, migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis

(2017) Siqi Xu et al.   INFLAMMATION RESEARCH

Level of inflammatory cytokines in rheumatoid arthritis patients: Correlation with 25-hydroxy vitamin D and reactive oxygen species

(2017) Somaiya Mateen et al.   PLoS One

Effect of nobiletin on the MAPK/NF-κB signaling pathway in the synovial membrane of rats with arthritis induced by collagen

(2017) Guliang Yang et al.   Food & Function

Electron transport chain inhibitors induce microglia activation through enhancing mitochondrial reactive oxygen species production

(2016) Junli Ye et al.   EXPERIMENTAL CELL RESEARCH

The bispecific antibody aimed at the vicious circle of IL-1β and IL-17A, is beneficial for the collagen-induced rheumatoid arthritis of mice through NF-κB signaling pathway

(2016) Qiang Wu et al.   IMMUNOLOGY LETTERS

Demethylation of an NF-κB enhancer element orchestrates iNOS induction in osteoarthritis and is associated with altered chondrocyte cell cycle

(2016) M.C. de Andrés et al.   OSTEOARTHRITIS AND CARTILAGE

Increased Reactive Oxygen Species Formation and Oxidative Stress in Rheumatoid Arthritis

(2016) Somaiya Mateen et al.   PLoS One

Homocysteine elicits an M1 phenotype in murine macrophages through an EMMPRIN-mediated pathway

(2015) Lee J. Winchester et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Cyclin D1/Cdk4 increases the transcriptional activity of FOXM1c without phosphorylating FOXM1c

(2013) Inken Wierstra   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer

(2012) Albert S. Baldwin   IMMUNOLOGICAL REVIEWS

Suppression of oxLDL-Induced MMP-9 and EMMPRIN Expression by Berberine via Inhibition of NF-κB Activation in Human THP-1 Macrophages

(2011) Zhouqing Huang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Andrographolide induces cell cycle arrest and apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes

(2011) Jie Yan et al.   CELL BIOLOGY AND TOXICOLOGY

Pro-inflammatory activities induced by CyPA–EMMPRIN interaction in monocytes

(2010) Wei Yuan et al.   ATHEROSCLEROSIS

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Expression of CD147 (EMMPRIN) on neutrophils in rheumatoid arthritis enhances chemotaxis, matrix metalloproteinase production and invasiveness of synoviocytes

(2010) Cong-Hua Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Inhibition of cyclin-dependent kinases by olomoucine and roscovitine reduces lipopolysaccharide-induced inflammatory responses via down-regulation of nuclear factor κB

(2009) R-S. Jhou et al.   CELL PROLIFERATION

Inhibitory effect of CD147/HAb18 monoclonal antibody on cartilage erosion and synovitis in the SCID mouse model for rheumatoid arthritis

(2009) J. Jia et al.   RHEUMATOLOGY

Extracellular Matrix Metalloproteinase Inducer (CD147) Is a Novel Receptor on Platelets, Activates Platelets, and Augments Nuclear Factor κB–Dependent Inflammation in Monocytes

(2007) Roland Schmidt et al.   CIRCULATION RESEARCH

EMMPRIN mediates β-adrenergic receptor-stimulated matrix metalloproteinase activity in cardiac myocytes

(2007) Deborah A. Siwik et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY