Osirisynes G-I, New Long-Chain Highly Oxygenated Polyacetylenes from the Mayotte Marine Sponge Haliclona sp.

In vitro and in silico insights into tyrosinase inhibitors with (E)-benzylidene-1-indanone derivatives

(2019) Hee Jin Jung et al.   Computational and Structural Biotechnology Journal

Targeting Fyn Kinase in Alzheimer’s Disease

(2018) Haakon B. Nygaard   BIOLOGICAL PSYCHIATRY

Marine Sponges and Bacteria as Challenging Sources of Enzyme Inhibitors for Pharmacological Applications

(2017) Nadia Ruocco et al.   Marine Drugs

Hypopigmenting Effects of Brown Algae-Derived Phytochemicals: A Review on Molecular Mechanisms

(2017) Mohammed Azam et al.   Marine Drugs

THZ1 targeting CDK7 suppresses STAT transcriptional activity and sensitizes T-cell lymphomas to BCL2 inhibitors

(2017) Florencia Cayrol et al.   Nature Communications

Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma

(2017) S A Greenall et al.   Oncogenesis

The role of sirtuins in aging and age-related diseases

(2016) Mateusz Wątroba et al.   Advances in Medical Sciences

Study of Ellagic Acid as a Natural Elastase Inhibitor by Spectroscopic Methods

(2016) X. Xing et al.   Journal of Applied Spectroscopy

In Vitro Dermo-Cosmetic Evaluation of Bark Extracts from Common Temperate Trees

(2016) Jane Hubert et al.   PLANTA MEDICA

Two new polyacetylene derivatives from the Red Sea sponge Xestospongia sp.

(2015) Seif-Eldin N. Ayyad et al.   ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES

Cyclin-Dependent Kinase 7 Controls mRNA Synthesis by Affecting Stability of Preinitiation Complexes, Leading to Altered Gene Expression, Cell Cycle Progression, and Survival of Tumor Cells

(2014) T. W. R. Kelso et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor

(2014) Nicholas Kwiatkowski et al.   NATURE

Fyn kinase inhibition as a novel therapy for Alzheimer’s disease

(2014) Haakon B Nygaard et al.   Alzheimers Research & Therapy

Regulation of proteasome activity in health and disease

(2013) Marion Schmidt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Photooxidation of Amplex red to resorufin: Implications of exposing the Amplex red assay to light

(2012) Baozhong Zhao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

Kinase Inhibitors from Marine Sponges

(2011) Danielle Skropeta et al.   Marine Drugs

Targeting the epigenome for treatment of cancer

(2011) E-J Geutjes et al.   ONCOGENE

Fulvynes, antimicrobial polyoxygenated acetylenes from the Mediterranean sponge Haliclona fulva

(2011) Genoveffa Nuzzo et al.   TETRAHEDRON

Evaluation of an Antibody-Free ADP Detection Assay: ADP-Glo

(2010) Hu Li et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Fyn

(2010) Yoshihito D. Saito et al.   CANCER

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

The secretases: enzymes with therapeutic potential in Alzheimer disease

(2010) Bart De Strooper et al.   Nature Reviews Neurology

Biosynthesis and function of polyacetylenes and allied natural products

(2008) Robert E. Minto et al.   PROGRESS IN LIPID RESEARCH

Identification of Geranic Acid, a Tyrosinase Inhibitor in Lemongrass (Cymbopogon citratus)

(2007) Toshiya Masuda et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY