IL-23 Promotes a Coordinated B Cell Germinal Center Program for Class-Switch Recombination to IgG2b in BXD2 Mice

With a Little Help from T Follicular Helper Friends: Humoral Immunity to Influenza Vaccination

(2019) Marios Koutsakos et al.   JOURNAL OF IMMUNOLOGY

Dysregulation of T Follicular Helper Cells in Lupus

(2019) John D. Mountz et al.   JOURNAL OF IMMUNOLOGY

T Follicular Helper Cell Biology: A Decade of Discovery and Diseases

(2019) Shane Crotty   IMMUNITY

Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress

(2019) Cecilia Domínguez Conde et al.   JOURNAL OF CLINICAL INVESTIGATION

Requirements for DNA bubble structure for efficient cleavage by helix–two-turn–helix DNA glycosylases

(2019) Kristina A Makasheva et al.   MUTAGENESIS

Maintenance of efficacy and safety of ustekinumab through 1 year in a randomized phase II trial of patients with active systemic lupus erythematosus

(2019) Ronald F. van Vollenhoven et al.   Arthritis & Rheumatology

Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1

(2019) Irina G. Minko et al.   DNA REPAIR

T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate

(2018) Wataru Ise et al.   IMMUNITY

Plasma cell output from germinal centers is regulated by signals from Tfh and stromal cells

(2018) Yang Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Distinct T Follicular Helper Cell Subset Infiltrates the Brain in Murine Neuropsychiatric Lupus

(2018) Shweta Jain et al.   Frontiers in Immunology

Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging

(2018) Isabelle Stewart et al.   IMMUNITY

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

(2018) Scott A. Jenks et al.   IMMUNITY

STAT4 and T-bet control follicular helper T cell development in viral infections

(2017) Jason S. Weinstein et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells

(2017) Nike J. Kräutler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reversed graph embedding resolves complex single-cell trajectories

(2017) Xiaojie Qiu et al.   NATURE METHODS

TFH cells progressively differentiate to regulate the germinal center response

(2016) Jason S Weinstein et al.   NATURE IMMUNOLOGY

Activation-Induced Cytidine Deaminase Expression in Human B Cell Precursors Is Essential for Central B Cell Tolerance

(2015) Tineke Cantaert et al.   IMMUNITY

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

T Follicular Helper Cell Differentiation, Function, and Roles in Disease

(2014) Shane Crotty   IMMUNITY

Clonal selection in the germinal centre by regulated proliferation and hypermutation

(2014) Alexander D. Gitlin et al.   NATURE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

IL-23 promotes TCR-mediated negative selection of thymocytes through the upregulation of IL-23 receptor and RORγt

(2014) Hao Li et al.   Nature Communications

Interleukin-21 Promotes Germinal Center Reaction by Skewing the Follicular Regulatory T Cell to Follicular Helper T Cell Balance in Autoimmune BXD2 Mice

(2014) Yanna Ding et al.   Arthritis & Rheumatology

IgG Subclasses and Allotypes: From Structure to Effector Functions

(2014) Gestur Vidarsson et al.   Frontiers in Immunology

The p40 Subunit of Interleukin (IL)-12 Promotes Stabilization and Export of the p35 Subunit

(2013) Rashmi Jalah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-17RA Is Essential for Optimal Localization of Follicular Th Cells in the Germinal Center Light Zone To Promote Autoantibody-Producing B Cells

(2013) Y. Ding et al.   JOURNAL OF IMMUNOLOGY

Break-Induced Replication Repair of Damaged Forks Induces Genomic Duplications in Human Cells

(2013) Lorenzo Costantino et al.   SCIENCE

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Identification of human germinal center light and dark zone cells and their relationship to human B-cell lymphomas

(2012) G. D. Victora et al.   BLOOD

Th17 cell-derived IL-17 is dispensable for B cell antibody production

(2012) Akiko Shibui et al.   CYTOKINE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice

(2011) Hui-Chen Hsu et al.   ARTHRITIS AND RHEUMATISM

Human Blood CXCR5+CD4+ T Cells Are Counterparts of T Follicular Cells and Contain Specific Subsets that Differentially Support Antibody Secretion

(2011) Rimpei Morita et al.   IMMUNITY

XRCC1 suppresses somatic hypermutation and promotes alternative nonhomologous end joining inIghgenes

(2011) Huseyin Saribasak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Optimizing transformations for automated, high throughput analysis of flow cytometry data

(2010) Greg Finak et al.   BMC BIOINFORMATICS

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4

(2010) Cristian Boboila et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-17 Activates the Canonical NF-κB Signaling Pathway in Autoimmune B Cells of BXD2 Mice To Upregulate the Expression of Regulators of G-Protein Signaling 16

(2010) Shutao Xie et al.   JOURNAL OF IMMUNOLOGY

Adenoviral-mediated, intratumor gene transfer of interleukin 23 induces a therapeutic antitumor response

(2009) J Reay et al.   CANCER GENE THERAPY

Calmodulin Mediates DNA Repair Pathways Involving H2AX in Response to Low-Dose Radiation Exposure of RAW 264.7 Macrophages

(2009) Heather S. Smallwood et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Marginal Zone Precursor B Cells as Cellular Agents for Type I IFN–Promoted Antigen Transport in Autoimmunity

(2009) John H. Wang et al.   JOURNAL OF IMMUNOLOGY

Fixing DNA breaks during class switch recombination: Figure 1.

(2008) Christopher J. Jolly et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Non-homologous end joining in class switch recombination: the beginning of the end

(2008) A. Kotnis et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES