Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS
出版年份 2020 全文链接
标题
Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 217, Issue 8, Pages -
出版商
Rockefeller University Press
发表日期
2020-07-16
DOI
10.1084/jem.20191734
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- SciPy 1.0: fundamental algorithms for scientific computing in Python
- (2020) Pauli Virtanen et al. NATURE METHODS
- 26S Proteasomes are rapidly activated by diverse hormones and physiological states that raise cAMP and cause Rpn6 phosphorylation
- (2019) Jordan J. S. VerPlank et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NF‐κB activation in astrocytes drives a stage‐specific beneficial neuroimmunological response in ALS
- (2018) Najwa Ouali Alami et al. EMBO JOURNAL
- Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS
- (2018) María de Lourdes Martínez-Silva et al. eLife
- Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9
- (2018) Barbara Commisso et al. eLife
- Therapeutic targeting of the pathological triad of extrasynaptic NMDA receptor signaling in neurodegenerations
- (2017) Hilmar Bading JOURNAL OF EXPERIMENTAL MEDICINE
- Cortical influences drive amyotrophic lateral sclerosis
- (2017) Andrew Eisen et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Changes in the Excitability of Neocortical Neurons in a Mouse Model of Amyotrophic Lateral Sclerosis Are Not Specific to Corticospinal Neurons and Are Modulated by Advancing Disease
- (2017) Juhyun Kim et al. JOURNAL OF NEUROSCIENCE
- Chronic electromyograms in treadmill running SOD1 mice reveal early changes in muscle activation
- (2017) Katharina A. Quinlan et al. JOURNAL OF PHYSIOLOGY-LONDON
- Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy
- (2017) Emily V Fletcher et al. NATURE NEUROSCIENCE
- Distinct roles for motor neuron autophagy early and late in the SOD1G93Amouse model of ALS
- (2017) Noam D. Rudnick et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ALS Clinical Trials Review: 20 Years of Failure. Are We Any Closer to Registering a New Treatment?
- (2017) Dmitry Petrov et al. Frontiers in Aging Neuroscience
- Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology
- (2016) Céline Ruegsegger et al. NEURON
- DREADD Modulation of Transplanted DA Neurons Reveals a Novel Parkinsonian Dyskinesia Mechanism Mediated by the Serotonin 5-HT6 Receptor
- (2016) Patrick Aldrin-Kirk et al. NEURON
- DREADDs for Neuroscientists
- (2016) Bryan L. Roth NEURON
- Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS
- (2016) Melanie Lalancette-Hebert et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice
- (2016) Saša Peter et al. Nature Communications
- Nuclear RNA-seq of single neurons reveals molecular signatures of activation
- (2016) Benjamin Lacar et al. Nature Communications
- Rab1-dependent ER–Golgi transport dysfunction is a common pathogenic mechanism in SOD1, TDP-43 and FUS-associated ALS
- (2015) Kai Y. Soo et al. ACTA NEUROPATHOLOGICA
- A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation
- (2015) Jian-Da Wang et al. Autophagy
- Multisensory Signaling Shapes Vestibulo-Motor Circuit Specificity
- (2015) Emanuela Basaldella et al. CELL
- Altered Functionality, Morphology, and Vesicular Glutamate Transporter Expression of Cortical Motor Neurons from a Presymptomatic Mouse Model of Amyotrophic Lateral Sclerosis
- (2015) L. Saba et al. CEREBRAL CORTEX
- Degeneration of proprioceptive sensory nerve endings in mice harboring amyotrophic lateral sclerosis-causing mutations
- (2015) Sydney K. Vaughan et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Postactivation depression of the Ia EPSP in motoneurons is reduced in both the G127X SOD1 model of amyotrophic lateral sclerosis and in aged mice
- (2015) A. Hedegaard et al. JOURNAL OF NEUROPHYSIOLOGY
- The ImageJ ecosystem: An open platform for biomedical image analysis
- (2015) Johannes Schindelin et al. MOLECULAR REPRODUCTION AND DEVELOPMENT
- From Intrinsic Firing Properties to Selective Neuronal Vulnerability in Neurodegenerative Diseases
- (2015) Francesco Roselli et al. NEURON
- cAMP-induced phosphorylation of 26S proteasomes on Rpn6/PSMD11 enhances their activity and the degradation of misfolded proteins
- (2015) Sudarsanareddy Lokireddy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Normal Distribution of VGLUT1 Synapses on Spinal Motoneuron Dendrites and Their Reorganization after Nerve Injury
- (2014) T. M. Rotterman et al. JOURNAL OF NEUROSCIENCE
- Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis
- (2014) Nicolas Delestrée et al. JOURNAL OF PHYSIOLOGY-LONDON
- Presynaptic inhibition of spinal sensory feedback ensures smooth movement
- (2014) Andrew J. P. Fink et al. NATURE
- Transcriptional regulation of autophagy by an FXR–CREB axis
- (2014) Sunmi Seok et al. NATURE
- A Computational Model of Motor Neuron Degeneration
- (2014) Gwendal Le Masson et al. NEURON
- PKA-GluA1 Coupling via AKAP5 Controls AMPA Receptor Phosphorylation and Cell-Surface Targeting during Bidirectional Homeostatic Plasticity
- (2014) Graham H. Diering et al. NEURON
- Degradation of mouse locomotor pattern in the absence of proprioceptive sensory feedback
- (2014) Turgay Akay et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Purines released from astrocytes inhibit excitatory synaptic transmission in the ventral horn of the spinal cord
- (2014) Eva Meier Carlsen et al. Frontiers in Neural Circuits
- Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis
- (2014) Félix Leroy et al. eLife
- Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons
- (2014) Vera van Dis et al. Acta Neuropathologica Communications
- Projections from the lateral vestibular nucleus to the spinal cord in the mouse
- (2013) Huazheng Liang et al. Brain Structure & Function
- Nuclear calcium signalling in the regulation of brain function
- (2013) Hilmar Bading NATURE REVIEWS NEUROSCIENCE
- Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival
- (2013) Smita Saxena et al. NEURON
- A Gαs DREADD Mouse for Selective Modulation of cAMP Production in Striatopallidal Neurons
- (2013) Martilias S Farrell et al. NEUROPSYCHOPHARMACOLOGY
- SMN Is Required for Sensory-Motor Circuit Function in Drosophila
- (2012) Wendy L. Imlach et al. CELL
- A Kinase Anchor Protein 150 (AKAP150)-associated Protein Kinase A Limits Dendritic Spine Density
- (2011) Yuan Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Permanent central synaptic disconnection of proprioceptors after nerve injury and regeneration. I. Loss of VGLUT1/IA synapses on motoneurons
- (2011) Francisco J. Alvarez et al. JOURNAL OF NEUROPHYSIOLOGY
- Learning-related feedforward inhibitory connectivity growth required for memory precision
- (2011) Sarah Ruediger et al. NATURE
- Early Functional Impairment of Sensory-Motor Connectivity in a Mouse Model of Spinal Muscular Atrophy
- (2011) George Z. Mentis et al. NEURON
- Chemical and Genetic Engineering of Selective Ion Channel-Ligand Interactions
- (2011) C. J. Magnus et al. SCIENCE
- Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
- (2010) Jeffrey D. Rothstein ANNALS OF NEUROLOGY
- Loss of ALS2/Alsin Exacerbates Motor Dysfunction in a SOD1H46R-Expressing Mouse ALS Model by Disturbing Endolysosomal Trafficking
- (2010) Shinji Hadano et al. PLoS One
- Fast Kinetics, High-Frequency Oscillations, and Subprimary Firing Range in Adult Mouse Spinal Motoneurons
- (2009) M. Manuel et al. JOURNAL OF NEUROSCIENCE
- Disassembly of Shank and Homer Synaptic Clusters Is Driven by Soluble β-Amyloid1-40 through Divergent NMDAR-Dependent Signalling Pathways
- (2009) Francesco Roselli et al. PLoS One
- Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4
- (2008) Barbara Beyer et al. HUMAN MOLECULAR GENETICS
- Stable synaptic retention of serine-880-phosphorylated GluR2 in hippocampal neurons
- (2008) Bradley A. States et al. MOLECULAR AND CELLULAR NEUROSCIENCE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now