In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET

Synaptic Changes in Parkinson Disease Assessed with in vivo Imaging

(2020) David Matuskey et al.   ANNALS OF NEUROLOGY

Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats

(2020) Ellis Chika Onwordi et al.   Nature Communications

In vivo synaptic density imaging with 11C-UCB-J detects treatment effects of saracatinib (AZD0530) in a mouse model of Alzheimer’s disease.

(2019) Takuya Toyonaga et al.   JOURNAL OF NUCLEAR MEDICINE

Lower synaptic density is associated with depression severity and network alterations

(2019) Sophie E. Holmes et al.   Nature Communications

Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging

(2018) Ming-Kai Chen et al.   JAMA Neurology

PET imaging of synaptic density: A new tool for investigation of neuropsychiatric diseases

(2018) Zhengxin Cai et al.   NEUROSCIENCE LETTERS

Kinetic evaluation and test–retest reproducibility of [11C]UCB-J, a novel radioligand for positron emission tomography imaging of synaptic vesicle glycoprotein 2A in humans

(2017) Sjoerd J Finnema et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

(2016) N. B. Nabulsi et al.   JOURNAL OF NUCLEAR MEDICINE

Dopamine synapse is a neuroligin-2–mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures

(2016) Motokazu Uchigashima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neonatal domoic acid alters in vivo binding of [11C]yohimbine to α2-adrenoceptors in adult rat brain

(2016) Majken B. Thomsen et al.   PSYCHOPHARMACOLOGY

Imaging synaptic density in the living human brain

(2016) Sjoerd J. Finnema et al.   Science Translational Medicine

Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands

(2014) Joël Mercier et al.   ChemMedChem

Evaluation of 18F-UCB-H as a Novel PET Tracer for Synaptic Vesicle Protein 2A in the Brain

(2014) G. I. Warnock et al.   JOURNAL OF NUCLEAR MEDICINE

Beta-amyloid oligomers induce early loss of presynaptic proteins in primary neurons by caspase-dependent and proteasome-dependent mechanisms

(2014) Bong Geum Jang et al.   NEUROREPORT

α-Synuclein Vaccination Prevents the Accumulation of Parkinson Disease-Like Pathologic Inclusions in Striatum in Association With Regulatory T Cell Recruitment in a Rat Model

(2013) Vanesa Sanchez-Guajardo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Quinolinic Acid: An Endogenous Neurotoxin with Multiple Targets

(2013) Rafael Lugo-Huitrón et al.   Oxidative Medicine and Cellular Longevity

Measuring dopaminergic function in the 6-OHDA-lesioned rat: a comparison of PET and microdialysis

(2013) Matthew D Walker et al.   EJNMMI Research

Presynaptic dysfunction in Huntington's disease

(2010) José L. Rozas et al.   BIOCHEMICAL SOCIETY TRANSACTIONS