Nesprins are mechanotransducers that discriminate epithelial–mesenchymal transition programs

EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration

(2018) Nicole M. Aiello et al.   DEVELOPMENTAL CELL

Sun-mediated mechanical LINC between nucleus and cytoskeleton regulates βcatenin nuclear access

(2018) Gunes Uzer et al.   JOURNAL OF BIOMECHANICS

Src- and confinement-dependent FAK activation causes E-cadherin relaxation and β-catenin activity

(2018) Charlène Gayrard et al.   JOURNAL OF CELL BIOLOGY

Mechanotransduction via the LINC complex regulates DNA replication in myonuclei

(2018) Shuoshuo Wang et al.   JOURNAL OF CELL BIOLOGY

Nanopillar force measurements reveal actin-cap-mediated YAP mechanotransduction

(2018) Jau-Ye Shiu et al.   NATURE CELL BIOLOGY

EMT and MET: necessary or permissive for metastasis?

(2017) Mohit Kumar Jolly et al.   Molecular Oncology

Nuclear envelopathies: a complex LINC between nuclear envelope and pathology

(2017) Alexandre Janin et al.   Orphanet Journal of Rare Diseases

Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension

(2016) Paul T. Arsenovic et al.   BIOPHYSICAL JOURNAL

FRET-based Molecular Tension Microscopy

(2016) Charlène Gayrard et al.   METHODS

Coordination between Intra- and Extracellular Forces Regulates Focal Adhesion Dynamics

(2016) Bibhu Ranjan Sarangi et al.   NANO LETTERS

Transcription upregulation via force-induced direct stretching of chromatin

(2016) Arash Tajik et al.   NATURE MATERIALS

The mammalian LINC complex regulates genome transcriptional responses to substrate rigidity

(2016) Samer G. Alam et al.   Scientific Reports

Cytoskeletal to Nuclear Strain Transfer Regulates YAP Signaling in Mesenchymal Stem Cells

(2015) Tristan P. Driscoll et al.   BIOPHYSICAL JOURNAL

Controlling Cell Geometry Affects the Spatial Distribution of Load Across Vinculin

(2015) Katheryn E. Rothenberg et al.   Cellular and Molecular Bioengineering

Design of a microfluidic device to quantify dynamic intra-nuclear deformation during cell migration through confining environments

(2015) Patricia M. Davidson et al.   Integrative Biology

Erk regulation of actin capping and bundling by Eps8 promotes cortex tension and leader bleb-based migration

(2015) Jeremy S Logue et al.   eLife

A role for nuclear envelope–bridging complexes in homology-directed repair

(2014) Rebecca K. Swartz et al.   MOLECULAR BIOLOGY OF THE CELL

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

(2014) Matthew J. Paszek et al.   NATURE

Isolated nuclei adapt to force and reveal a mechanotransduction pathway in the nucleus

(2014) Christophe Guilluy et al.   NATURE CELL BIOLOGY

 -Catenin is an inhibitor of transcription

(2014) R. L. Daugherty et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

 -Catenin interacts with APC to regulate  -catenin proteolysis and transcriptional repression of Wnt target genes

(2013) S. H. Choi et al.   GENES & DEVELOPMENT

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction

(2013) Allison B. Chambliss et al.   Scientific Reports

Samp1 is a component of TAN lines and is required for nuclear movement

(2012) J. Borrego-Pinto et al.   JOURNAL OF CELL SCIENCE

E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch

(2012) N. Borghi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin cap associated focal adhesions and their distinct role in cellular mechanosensing

(2012) Dong-Hwee Kim et al.   Scientific Reports

Real-time observation of flow-induced cytoskeletal stress in living cells

(2011) Jason Rahimzadeh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Bright and stable near-infrared fluorescent protein for in vivo imaging

(2011) Grigory S Filonov et al.   NATURE BIOTECHNOLOGY

External forces control mitotic spindle positioning

(2011) Jenny Fink et al.   NATURE CELL BIOLOGY

Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development

(2010) K. Natalie Randles et al.   DEVELOPMENTAL DYNAMICS

Nesprin-2 Interacts with α-Catenin and Regulates Wnt Signaling at the Nuclear Envelope

(2010) Sascha Neumann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

(2010) Carsten Grashoff et al.   NATURE

Regulation of cell motile behavior by crosstalk between cadherin- and integrin-mediated adhesions

(2010) N. Borghi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Linear Arrays of Nuclear Envelope Proteins Harness Retrograde Actin Flow for Nuclear Movement

(2010) G. W. G. Luxton et al.   SCIENCE

Activity of the β-catenin phosphodestruction complex at cell–cell contacts is enhanced by cadherin-based adhesion

(2009) Meghan T. Maher et al.   JOURNAL OF CELL BIOLOGY

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of an improved donor fluorescent protein for Förster resonance energy transfer microscopy

(2008) Richard N. Day et al.   JOURNAL OF BIOMEDICAL OPTICS