Mechanotransduction via the LINC complex regulates DNA replication in myonuclei

EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration

(2017) Jinyi Xiang et al.   Nature Communications

Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension

(2016) Paul T. Arsenovic et al.   BIOPHYSICAL JOURNAL

Mechanical regulation of transcription controls Polycomb-mediated gene silencing during lineage commitment

(2016) Huy Quang Le et al.   NATURE CELL BIOLOGY

Transcription upregulation via force-induced direct stretching of chromatin

(2016) Arash Tajik et al.   NATURE MATERIALS

Cell-type-specific profiling of protein–DNA interactions without cell isolation using targeted DamID with next-generation sequencing

(2016) Owen J Marshall et al.   Nature Protocols

Nongenetic functions of the genome

(2016) M. Bustin et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

damidseq_pipeline: an automated pipeline for processing DamID sequencing datasets: Fig. 1.

(2015) Owen J. Marshall et al.   BIOINFORMATICS

Polyploidy

(2015) Laura E. Frawley et al.   CURRENT BIOLOGY

Networking in the nucleus: a spotlight on LEM-domain proteins

(2015) Lacy J Barton et al.   CURRENT OPINION IN CELL BIOLOGY

Barrier to Autointegration Factor (BANF1): interwoven roles in nuclear structure, genome integrity, innate immunity, stress responses and progeria

(2015) Augusta Jamin et al.   CURRENT OPINION IN CELL BIOLOGY

Amphiphysin 2 Orchestrates Nucleus Positioning and Shape by Linking the Nuclear Envelope to the Actin and Microtubule Cytoskeleton

(2015) Manuela D’Alessandro et al.   DEVELOPMENTAL CELL

LINC'ing form and function at the nuclear envelope

(2015) Peter Meinke et al.   FEBS LETTERS

Lamins at the crossroads of mechanosignaling

(2015) Selma Osmanagic-Myers et al.   GENES & DEVELOPMENT

Nesprin provides elastic properties to muscle nuclei by cooperating with spectraplakin and EB1

(2015) Shuoshuo Wang et al.   JOURNAL OF CELL BIOLOGY

Accessorizing and anchoring the LINC complex for multifunctionality

(2015) Wakam Chang et al.   JOURNAL OF CELL BIOLOGY

When bigger is better: the role of polyploidy in organogenesis

(2015) Terry L. Orr-Weaver   TRENDS IN GENETICS

Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes

(2015) Manuela Loi et al.   Oncotarget

Mechanisms and dynamics of nuclear lamina–genome interactions

(2014) Mario Amendola et al.   CURRENT OPINION IN CELL BIOLOGY

Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells

(2014) M. H. Wilson et al.   DEVELOPMENT

The Drosophila KASH domain proteins Msp-300 and Klarsicht and the SUN domain protein Klaroid have no essential function during oogenesis

(2014) Martin Technau et al.   FLY

The SUN protein UNC-84 is required only in force-bearing cells to maintain nuclear envelope architecture

(2014) Natalie E. Cain et al.   JOURNAL OF CELL BIOLOGY

The nuclear lamina is mechano-responsive to ECM elasticity in mature tissue

(2014) J. Swift et al.   JOURNAL OF CELL SCIENCE

Materials as stem cell regulators

(2014) William L. Murphy et al.   NATURE MATERIALS

BoxPlotR: a web tool for generation of box plots

(2014) Michaela Spitzer et al.   NATURE METHODS

Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth

(2014) Bruce A. Edgar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Fly-FUCCI: A Versatile Tool for Studying Cell Proliferation in Complex Tissues

(2014) Norman Zielke et al.   Cell Reports

SUN proteins and nuclear envelope spacing

(2014) Natalie E Cain et al.   Nucleus

Remanent cell traction force in renal vascular smooth muscle cells induced by integrin-mediated mechanotransduction

(2013) Lavanya Balasubramanian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Translocating myonuclei have distinct leading and lagging edges that require Kinesin and Dynein

(2013) E. S. Folker et al.   DEVELOPMENT

Cell-Type-Specific Profiling of Gene Expression and Chromatin Binding without Cell Isolation: Assaying RNA Pol II Occupancy in Neural Stem Cells

(2013) Tony D. Southall et al.   DEVELOPMENTAL CELL

Nesprins: from the nuclear envelope and beyond

(2013) Dipen Rajgor et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Lamin A/C and emerin regulate MKL1–SRF activity by modulating actin dynamics

(2013) Chin Yee Ho et al.   NATURE

Biophysical regulation of epigenetic state and cell reprogramming

(2013) Timothy L. Downing et al.   NATURE MATERIALS

High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states

(2013) Ronnie Blecher-Gonen et al.   Nature Protocols

Endoreplication

(2013) N. Zielke et al.   Cold Spring Harbor Perspectives in Biology

The nuclear envelope LEM-domain protein emerin

(2013) Jason M Berk et al.   Nucleus

β1 Integrin Gene Excision in the Adult Murine Cardiac Myocyte Causes Defective Mechanical and Signaling Responses

(2012) Ruixia Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Chromatin Decondensation and Nuclear Softening Accompany Nanog Downregulation in Embryonic Stem Cells

(2012) Kevin J. Chalut et al.   BIOPHYSICAL JOURNAL

Endoreplication and polyploidy: insights into development and disease

(2012) D. T. Fox et al.   DEVELOPMENT

Organelle positioning in muscles requires cooperation between two KASH proteins and microtubules

(2012) Hadas Elhanany-Tamir et al.   JOURNAL OF CELL BIOLOGY

MAP and kinesin-dependent nuclear positioning is required for skeletal muscle function

(2012) Thomas Metzger et al.   NATURE

Extracellular-matrix tethering regulates stem-cell fate

(2012) Britta Trappmann et al.   NATURE MATERIALS

The nuclear lamins: flexibility in function

(2012) Brian Burke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biophysical Regulation of Histone Acetylation in Mesenchymal Stem Cells

(2011) Yuan Li et al.   BIOPHYSICAL JOURNAL

Nuclear organization: taking a position on gene expression

(2011) Pamela K Geyer et al.   CURRENT OPINION IN CELL BIOLOGY

Microtubule-induced nuclear envelope fluctuations control chromatin dynamics in Drosophila embryos

(2011) Bernhard Hampoelz et al.   DEVELOPMENT

The Interaction between Nesprins and Sun Proteins at the Nuclear Envelope Is Critical for Force Transmission between the Nucleus and Cytoskeleton

(2011) Maria L. Lombardi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactions Between Nuclei and the Cytoskeleton Are Mediated by SUN-KASH Nuclear-Envelope Bridges

(2010) Daniel A. Starr et al.   Annual Review of Cell and Developmental Biology

Regulation of Cardiomyocyte Polyploidy and Multinucleation by CyclinG1

(2010) Zhipei Liu et al.   CIRCULATION RESEARCH

Mechanisms of mechanical signaling in development and disease

(2010) P. A. Janmey et al.   JOURNAL OF CELL SCIENCE

Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila

(2009) F. Demontis et al.   DEVELOPMENT

Endoreplication: polyploidy with purpose

(2009) H. O. Lee et al.   GENES & DEVELOPMENT

Mutation of SYNE-1, encoding an essential component of the nuclear lamina, is responsible for autosomal recessive arthrogryposis

(2009) R. Attali et al.   HUMAN MOLECULAR GENETICS

Nesprin-1 mutations in human and murine cardiomyopathy

(2009) Megan J. Puckelwartz et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Barrier-to-autointegration factor (BAF) condenses DNA by looping

(2009) D. Skoko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for Cardiomyocyte Renewal in Humans

(2009) Olaf Bergmann et al.   SCIENCE

Global Analysis of Short RNAs Reveals Widespread Promoter-Proximal Stalling and Arrest of Pol II in Drosophila

(2009) S. Nechaev et al.   SCIENCE

Nuclear Shape, Mechanics, and Mechanotransduction

(2008) Kris Noel Dahl et al.   CIRCULATION RESEARCH

Disruption of nesprin-1 produces an Emery Dreifuss muscular dystrophy-like phenotype in mice

(2008) M. J. Puckelwartz et al.   HUMAN MOLECULAR GENETICS

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY