Structural Isomerism and Enhanced Lipophilicity of Pyrithione Ligands of Organoruthenium(II) Complexes Increase Inhibition on AChE and BuChE

Improving Anti-Neurodegenerative Benefits of Acetylcholinesterase Inhibitors in Alzheimer’s Disease: Are Irreversible Inhibitors the Future?

(2020) Donald E. Moss   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Binding Kinetics of Ruthenium Pyrithione Chemotherapeutic Candidates to Human Serum Proteins Studied by HPLC-ICP-MS

(2020) Katarina Marković et al.   MOLECULES

Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives—Anticancer and Cholinesterase-Inhibiting Activity

(2020) Jakub Jończyk et al.   MOLECULES

Metal Ions in Alzheimer’s Disease: A Key Role or Not?

(2019) Yan Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Alzheimer’s Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts

(2019) Camila Fabiani et al.   Frontiers in Cellular Neuroscience

Towards Identification of Essential Structural Elements of Organoruthenium(II)‐Pyrithionato Complexes for Anticancer Activity

(2019) Jerneja Kladnik et al.   CHEMISTRY-A EUROPEAN JOURNAL

Covalent versus Noncovalent Binding of Ruthenium η 6 ‐ p ‐Cymene Complexes to Zinc‐Finger Protein NCp7

(2019) Yaping Sheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Inhibition of acetylcholinesterase activity and β‑amyloid oligomer formation by 6‑bromotryptamine�A, a multi‑target anti‑Alzheimer's molecule

(2019) Xiaofeng Jin et al.   Oncology Letters

Acetylcholinesterase and Aβ Aggregation Inhibition by Heterometallic Ruthenium(II)–Platinum(II) Polypyridyl Complexes

(2018) Nilima A. Vyas et al.   INORGANIC CHEMISTRY

Isosteres of hydroxypyridinethione as drug-like pharmacophores for metalloenzyme inhibition

(2018) Rebecca N. Adamek et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Increasing Polarity in Tacrine and Huprine Derivatives: Potent Anticholinesterase Agents for the Treatment of Myasthenia Gravis

(2018) Carles Galdeano et al.   MOLECULES

Organoruthenium Prodrugs as a New Class of Cholinesterase and Glutathione-S-Transferase Inhibitors

(2018) Samuel Ristovski et al.   ChemMedChem

Aluminum and Alzheimer's Disease: After a Century of Controversy, Is there a Plausible Link?

(2018) Lucija Tomljenovic   JOURNAL OF ALZHEIMERS DISEASE

Efficacy and Safety of Donepezil, Galantamine, Rivastigmine, and Memantine for the Treatment of Alzheimer's Disease: A Systematic Review and Meta-Analysis

(2018) Chen-Chen Tan et al.   JOURNAL OF ALZHEIMERS DISEASE

Discorhabdin alkaloids from Antarctic Latrunculia spp. sponges as a new class of cholinesterase inhibitors

(2017) Tanja Botić et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sunitinib, a Clinically Used Anticancer Drug, Is a Potent AChE Inhibitor and Attenuates Cognitive Impairments in Mice

(2016) Ling Huang et al.   ACS Chemical Neuroscience

Pyrithione-based ruthenium complexes as inhibitors of aldo–keto reductase 1C enzymes and anticancer agents

(2016) Jakob Kljun et al.   DALTON TRANSACTIONS

Ruthenium(II) polypyridyl complexes with hydrophobic ancillary ligand as Aβ aggregation inhibitors

(2016) Nilima A. Vyas et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Structure-Related Mode-of-Action Differences of Anticancer Organoruthenium Complexes with β-Diketonates

(2015) Sara Seršen et al.   JOURNAL OF MEDICINAL CHEMISTRY

The keystone of Alzheimer pathogenesis might be sought in Aβ physiology

(2015) D. Puzzo et al.   NEUROSCIENCE

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Ruthenium(II) polypyridyl complex as inhibitor of acetylcholinesterase and Aβ aggregation

(2014) Nilima A. Vyas et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Inhibitors of Acetylcholinesterase and Butyrylcholinesterase Meet Immunity

(2014) Miroslav Pohanka   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exploring the Influence of the Protein Environment on Metal-Binding Pharmacophores

(2014) David P. Martin et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Clinical Problem of Symptomatic Alzheimer Disease and Mild Cognitive Impairment

(2013) R. Tarawneh et al.   Cold Spring Harbor Perspectives in Medicine

Synthesis, spectroscopic characterization, photochemical and photophysical properties and biological activities of ruthenium complexes with mono- and bi-dentate histamine ligand

(2012) Carolina R. Cardoso et al.   DALTON TRANSACTIONS

Coordinating ability of anions and solvents towards transition metals and lanthanides

(2011) Raúl Díaz-Torres et al.   DALTON TRANSACTIONS

Lipophilicity in drug discovery

(2010) Michael J Waring   Expert Opinion on Drug Discovery

First Ruthenium Organometallic Complex of Antibacterial Agent Ofloxacin. Crystal Structure and Interactions with DNA

(2010) Iztok Turel et al.   INORGANIC CHEMISTRY

Synthesis, X-ray diffraction structure, spectroscopic properties and antiproliferative activity of a novel ruthenium complex with constitutional similarity to cisplatin

(2009) Sanja Grguric-Sipka et al.   DALTON TRANSACTIONS

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

4-Substituted 1-Acyloxypyridine-2(1H)-thiones: Experimental and Computational Studies of the Substituent Effect on Electronic Absorption Spectra†

(2009) Aleksandra Jankowiak et al.   JOURNAL OF ORGANIC CHEMISTRY

Solid-Phase Synthesis of Tris-heteroleptic Ruthenium(II) Complexes and Application to Acetylcholinesterase Inhibition

(2008) Seann P. Mulcahy et al.   INORGANIC CHEMISTRY