Effects of Short-Chain Fatty Acids on Human Oral Epithelial Cells and the Potential Impact on Periodontal Disease: A Systematic Review of In Vitro Studies

Sodium butyrate inhibits migration and induces AMPK‐mTOR pathway‐dependent autophagy and ROS‐mediated apoptosis via the miR‐139‐5p/Bmi‐1 axis in human bladder cancer cells

(2020) Feifan Wang et al.   FASEB JOURNAL

Butyrate Decreases ICAM-1 Expression in Human Oral Squamous Cell Carcinoma Cells

(2020) Gabriel Leonardo Magrin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease

(2020) David M. Kaye et al.   CIRCULATION

Sodium butyrate attenuated neuronal apoptosis via GPR41/Gβγ/PI3K/Akt pathway after MCAO in rats

(2020) Zhenhua Zhou et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid–Mediated Activation of G Protein–Coupled Receptors GPR43 and GPR109A

(2020) Yan Jun Li et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Sodium butyrate protects against oxidative stress in human nucleus pulposus cells via elevating PPARγ-regulated Klotho expression

(2020) Xinxin Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Osteoimmunology: inflammatory osteolysis and regeneration of the alveolar bone

(2019) Reinhard Gruber   JOURNAL OF CLINICAL PERIODONTOLOGY

The influence of an anti‐inflammatory diet on gingivitis. A randomized controlled trial

(2019) Johan P. Woelber et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

In Vitro Evaluation of Apoptotic Induction of Butyric Acid Derivatives in Colorectal Carcinoma Cells

(2019) LIJI PATTAYIL et al.   ANTICANCER RESEARCH

Sodium butyrate induces autophagic apoptosis of nasopharyngeal carcinoma cells by inhibiting AKT/mTOR signaling

(2019) Wei Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Butyrate Rather than LPS Subverts Gingival Epithelial Homeostasis by Downregulation of Intercellular Junctions and Triggering Pyroptosis

(2019) Juan Liu et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

ATG7 is essential for secretion of iron from ameloblasts and normal growth of murine incisors during aging

(2019) Supawadee Sukseree et al.   Autophagy

Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions

(2018) Iain L.C. Chapple et al.   JOURNAL OF PERIODONTOLOGY

Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss

(2018) Sébastien Lucas et al.   Nature Communications

Time and Concentration Dependent Effects of Short Chain Fatty Acids on Lipopolysaccharide- or Tumor Necrosis Factor α-Induced Endothelial Activation

(2018) Meng Li et al.   Frontiers in Pharmacology

A short-chain fatty acid, propionate, enhances the cytotoxic effect of cisplatin by modulating GPR41 signaling pathways in HepG2 cells

(2018) Mamiko Kobayashi et al.   Oncotarget

Necroptosis in the periodontal homeostasis: Signals emanating from dying cells

(2017) J Li et al.   ORAL DISEASES

Periodontal diseases

(2017) Denis F. Kinane et al.   Nature Reviews Disease Primers

Fatty acids as modulators of neutrophil recruitment, function and survival

(2016) Hosana G. Rodrigues et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Combined effects of starvation and butyrate on autophagy-dependent gingival epithelial cell death

(2016) M. Evans et al.   JOURNAL OF PERIODONTAL RESEARCH

Butyrate attenuates lipolysis in adipocytes co-cultured with macrophages through non-prostaglandin E2–mediated and prostaglandin E2–mediated pathways

(2016) Hideo Ohira et al.   Lipids in Health and Disease

Re-discovering periodontal butyric acid: New insights on an old metabolite

(2016) Marni E. Cueno et al.   MICROBIAL PATHOGENESIS

Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43

(2016) W Wu et al.   Mucosal Immunology

SCFA Receptors in Pancreatic β Cells: Novel Diabetes Targets?

(2016) Medha Priyadarshini et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Erratum to: An oral health optimized diet can reduce gingival and periodontal inflammation in humans - a randomized controlled pilot study

(2016) J. P. Woelber et al.   BMC Oral Health

Revisit dietary fiber on colorectal cancer: butyrate and its role on prevention and treatment

(2015) J. C. Encarnação et al.   CANCER AND METASTASIS REVIEWS

Short-chain fatty acids in control of body weight and insulin sensitivity

(2015) Emanuel E. Canfora et al.   Nature Reviews Endocrinology

In vitro Anti-Tumor Effects of Statins on Head and Neck Squamous Cell Carcinoma: A Systematic Review

(2015) Ludmila Madeira Cardoso Pavan et al.   PLoS One

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis

(2014) Nagendra Singh et al.   IMMUNITY

Effect of non-surgical periodontal treatment on short chain fatty acid levels in gingival crevicular fluid of patients with generalized aggressive periodontitis

(2013) R. Lu et al.   JOURNAL OF PERIODONTAL RESEARCH

Pre- and Posttherapy Assessment of Intestinal Soluble Mediators in IBD: Where We Stand and Future Perspectives

(2013) F. Scaldaferri et al.   MEDIATORS OF INFLAMMATION

Dietary Fiber Intake and Risk of First Stroke

(2013) Diane E. Threapleton et al.   STROKE

Bacteria, Colonic Fermentation, and Gastrointestinal Health

(2012) George T. Macfarlane et al.   JOURNAL OF AOAC INTERNATIONAL

Butyrate-induced GPR41 Activation Inhibits Histone Acetylation and Cell Growth

(2012) Jin Wu et al.   Journal of Genetics and Genomics

GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables

(2011) Gordon Guyatt et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Butyrate, a bacterial metabolite, induces apoptosis and autophagic cell death in gingival epithelial cells

(2010) H. Tsuda et al.   JOURNAL OF PERIODONTAL RESEARCH

Short-chain fatty acids stimulate the migration of neutrophils to inflammatory sites

(2009) Marco A. R. Vinolo et al.   CLINICAL SCIENCE

Acetic Acid Upregulates the Expression of Genes for Fatty Acid Oxidation Enzymes in Liver To Suppress Body Fat Accumulation

(2009) Tomoo Kondo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Butyric Acid Induces Apoptosis in Inflamed Fibroblasts

(2009) T. Kurita-Ochiai et al.   JOURNAL OF DENTAL RESEARCH

Dietary Carbohydrates and Dental-Systemic Diseases

(2009) P. Hujoel   JOURNAL OF DENTAL RESEARCH

The Impact of the Stone Age Diet on Gingival Conditions in the Absence of Oral Hygiene

(2009) Stefan Baumgartner et al.   JOURNAL OF PERIODONTOLOGY

In vitro studies on the inhibition of colon cancer by butyrate and carnitine

(2009) Marie-Josée Roy et al.   NUTRITION

Butyrate and propionate induced activated or non-activated neutrophil apoptosis via HDAC inhibitor activity but without activating GPR-41/GPR-43 pathways

(2009) Michiko Aoyama et al.   NUTRITION

The effect of butyric acid on adhesion molecule expression by human gingival epithelial cells

(2008) S. Takigawa et al.   JOURNAL OF PERIODONTAL RESEARCH

Increased susceptibility to tumor necrosis factor-α in butyric acid-induced apoptosis is caused by downregulation of cFLIP expression in Jurkat T cells

(2008) Shintaro Seto et al.   MICROBIOLOGY AND IMMUNOLOGY

Effects of sodium bicarbonate on butyric acid-induced epithelial cell damage in vitro

(2008) Satoko Takigawa et al.   Journal of Oral Science