SIRT 7 activates quiescent hair follicle stem cells to ensure hair growth in mice

HDAC8 cooperates with SMAD3/4 complex to suppress SIRT7 and promote cell survival and migration

(2020) Xiaolong Tang et al.   NUCLEIC ACIDS RESEARCH

SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair

(2019) Ming Tang et al.   Science Advances

Stimulation of Hair Growth by Small Molecules that Activate Autophagy

(2019) Min Chai et al.   Cell Reports

Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth

(2018) Bettina Reichenbach et al.   EMBO JOURNAL

Cellular and epigenetic drivers of stem cell ageing

(2018) Maria Ermolaeva et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stem cells repurpose proliferation to contain a breach in their niche barrier

(2018) Kenneth Lay et al.   eLife

Advances in Cellular Characterization of the Sirtuin Isoform, SIRT7

(2018) Di Wu et al.   Frontiers in Endocrinology

SIRT7 antagonizes TGF-β signaling and inhibits breast cancer metastasis

(2017) Xiaolong Tang et al.   Nature Communications

SIRT7 promotes genome integrity and modulates non‐homologous end joining DNA repair

(2016) Berta N Vazquez et al.   EMBO JOURNAL

Dermal adipocytes and hair cycling: is spatial heterogeneity a characteristic feature of the dermal adipose tissue depot?

(2016) Ilja L. Kruglikov et al.   EXPERIMENTAL DERMATOLOGY

Dermal-Epidermal Cross-Talk: Differential Interactions With Microvascular Endothelial Cells

(2016) Eleonora Bassino et al.   JOURNAL OF CELLULAR PHYSIOLOGY

FOXC1 maintains the hair follicle stem cell niche and governs stem cell quiescence to preserve long-term tissue-regenerating potential

(2016) Kenneth Lay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aging, alopecia, and stem cells

(2016) M. Lei et al.   SCIENCE

Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

(2016) H. Matsumura et al.   SCIENCE

Foxc1 reinforces quiescence in self-renewing hair follicle stem cells

(2016) L. Wang et al.   SCIENCE

SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability

(2016) Lei Li et al.   Nature Communications

Sirt7 Contributes to Myocardial Tissue Repair by Maintaining Transforming Growth Factor-β Signaling PathwayCLINICAL PERSPECTIVE

(2015) Satoshi Araki et al.   CIRCULATION

A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

(2015) M. Mohrin et al.   SCIENCE

A SIRT7-Dependent Acetylation Switch of GABPβ1 Controls Mitochondrial Function

(2014) Dongryeol Ryu et al.   Cell Metabolism

SIRT7 Controls Hepatic Lipid Metabolism by Regulating the Ubiquitin-Proteasome Pathway

(2014) Tatsuya Yoshizawa et al.   Cell Metabolism

Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation

(2014) J. Goldstein et al.   GENES & DEVELOPMENT

Signaling Involved in Hair Follicle Morphogenesis and Development

(2014) Pisal Rishikaysh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sirt1 Extends Life Span and Delays Aging in Mice through the Regulation of Nk2 Homeobox 1 in the DMH and LH

(2013) Akiko Satoh et al.   Cell Metabolism

Nfatc1 orchestrates aging in hair follicle stem cells

(2013) B. E. Keyes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

REG  deficiency promotes premature aging via the casein kinase 1 pathway

(2013) L. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease

(2013) Jiyung Shin et al.   Cell Reports

Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation

(2012) Naoki Oshimori et al.   Cell Stem Cell

P-Cadherin Regulates Human Hair Growth and Cycling via Canonical Wnt Signaling and Transforming Growth Factor-β2

(2012) Liat Samuelov et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

RANKL induces NFATc1 acetylation and stability via histone acetyltransferases during osteoclast differentiation

(2011) Jung Ha Kim et al.   BIOCHEMICAL JOURNAL

Dynamics between Stem Cells, Niche, and Progeny in the Hair Follicle

(2011) Ya-Chieh Hsu et al.   CELL

Expression of a Constitutively Active Calcineurin Encoded by an Intron-Retaining mRNA in Follicular Keratinocytes

(2011) Atsushi Fujimura et al.   PLoS One

Nuclear Factor I-C Regulates TGF-β-dependent Hair Follicle Cycling

(2010) Genta Plasari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

NFATc1 Balances Quiescence and Proliferation of Skin Stem Cells

(2008) Valerie Horsley et al.   CELL

REGγ, a proteasome activator and beyond?

(2008) I. Mao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Sirt7 Increases Stress Resistance of Cardiomyocytes and Prevents Apoptosis and Inflammatory Cardiomyopathy in Mice

(2008) Olesya Vakhrusheva et al.   CIRCULATION RESEARCH

Lgr5 marks cycling, yet long-lived, hair follicle stem cells

(2008) Viljar Jaks et al.   NATURE GENETICS