标题
New Insights into the Genetics of Latent Autoimmune Diabetes in Adults
作者
关键词
-
出版物
Current Diabetes Reports
Volume 20, Issue 9, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-07-28
DOI
10.1007/s11892-020-01330-y
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared to Type 1 Diabetes Mellitus
- (2020) Anne Jörns (A.J.) et al. DIABETES
- Time-varying risk of microvascular complications in latent autoimmune diabetes of adulthood compared with type 2 diabetes in adults: a post-hoc analysis of the UK Prospective Diabetes Study 30-year follow-up data (UKPDS 86)
- (2020) Ernesto Maddaloni et al. Lancet Diabetes & Endocrinology
- Distinct secretion pattern of serum proinsulin in different types of diabetes
- (2020) Yue Tong et al. Annals of Translational Medicine
- Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis
- (2019) Seth A. Sharp et al. DIABETES CARE
- The illusion of polygenic disease risk prediction
- (2019) Nicholas J. Wald et al. GENETICS IN MEDICINE
- Long‐term Risk of Cardiovascular Disease in Individuals with Latent Autoimmune Diabetes of Adults (UKPDS nnn)
- (2019) E. Maddaloni et al. DIABETES OBESITY & METABOLISM
- IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function
- (2019) Chiara Montemurro et al. Nature Communications
- Persistent C-peptide secretion in Type 1 diabetes and its relationship to the genetic architecture of diabetes
- (2019) Paul M. McKeigue et al. BMC Medicine
- Genetic Risk Scores for Diabetes Diagnosis and Precision Medicine
- (2019) Miriam S Udler et al. ENDOCRINE REVIEWS
- Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes
- (2019) Manuela Battaglia et al. DIABETES CARE
- Activation of the HIF1α/PFKFB3 stress response pathway in beta cells in type 1 diabetes
- (2019) Hiroshi Nomoto et al. DIABETOLOGIA
- Genetic Discrimination Between LADA and Childhood-Onset Type 1 Diabetes Within the MHC
- (2019) Rajashree Mishra et al. DIABETES CARE
- The Diabetes Gene and Wnt Pathway Effector TCF7L2 Regulates Adipocyte Development and Function
- (2018) Xi Chen et al. DIABETES
- Low-grade Inflammatory Marker Profile May Help to Differentiate Patients With LADA, Classic Adult-Onset Type 1 Diabetes, and Type 2 Diabetes
- (2018) Esmeralda Castelblanco et al. DIABETES CARE
- Global Economic Burden of Diabetes in Adults: Projections From 2015 to 2030
- (2018) Christian Bommer et al. DIABETES CARE
- Lower mortality and cardiovascular event rates in patients with Latent Autoimmune Diabetes In Adults (LADA) as compared with type 2 diabetes and insulin deficient diabetes: A cohort study of 4368 patients
- (2018) Mette Wod et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- Overweight, obesity and the risk of LADA: results from a Swedish case–control study and the Norwegian HUNT Study
- (2018) Rebecka Hjort et al. DIABETOLOGIA
- Autoimmunity-Associated PTPN22 Polymorphisms in Latent Autoimmune Diabetes of the Adult Differ from Those of Type 1 Diabetes Patients
- (2018) Petr Heneberg et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression
- (2018) Jennifer Schloss et al. JOURNAL OF IMMUNOLOGY
- Novel subgroups of adult-onset diabetes and their association with outcomes: a data-driven cluster analysis of six variables
- (2018) Emma Ahlqvist et al. Lancet Diabetes & Endocrinology
- Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
- (2018) Amit V. Khera et al. NATURE GENETICS
- Lnk/Sh2b3 Regulates Adipose Inflammation and Glucose Tolerance through Group 1 ILCs
- (2018) Taizo Mori et al. Cell Reports
- Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis
- (2018) Miriam S. Udler et al. PLOS MEDICINE
- A Type 1 Diabetes Genetic Risk Score Can Identify Patients With GAD65 Autoantibody–Positive Type 2 Diabetes Who Rapidly Progress to Insulin Therapy
- (2018) Anita L. Grubb et al. DIABETES CARE
- Shared genetic risk contributes to type 1 and type 2 diabetes etiology
- (2018) Anthony Aylward et al. HUMAN MOLECULAR GENETICS
- Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps
- (2018) Anubha Mahajan et al. NATURE GENETICS
- Association of common type 1 and type 2 diabetes gene variants with latent autoimmune diabetes in adults: A meta‐analysis
- (2018) Deepika Ramu et al. Journal of Diabetes
- The role of LNK/SH2B3 genetic alterations in myeloproliferative neoplasms and other hematological disorders
- (2017) N Maslah et al. LEUKEMIA
- Beta-Cell Fragility As a Common Underlying Risk Factor in Type 1 and Type 2 Diabetes
- (2017) Adrian Liston et al. TRENDS IN MOLECULAR MEDICINE
- Linking inflammation and hypertension via LNK/SH2B3
- (2016) Bethany L. Dale et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- Functional Domains of Autoimmune Regulator (AIRE) Modulate INS-VNTR Transcription in Human Thymic Epithelial Cells
- (2016) Avis E. Sparks et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HLA Genetic Discrepancy Between Latent Autoimmune Diabetes in Adults and Type 1 Diabetes: LADA China Study No. 6
- (2016) Shuoming Luo et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes
- (2016) James Dooley et al. NATURE GENETICS
- Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes
- (2015) Martha Campbell-Thompson et al. DIABETES
- A Type 1 Diabetes Genetic Risk Score Can Aid Discrimination Between Type 1 and Type 2 Diabetes in Young Adults
- (2015) Richard A. Oram et al. DIABETES CARE
- Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
- (2015) Suna Onengut-Gumuscu et al. NATURE GENETICS
- Genetic Variations of PTPN2 and PTPN22: Role in the Pathogenesis of Type 1 Diabetes and Crohn's Disease
- (2015) Robert C. Sharp et al. Frontiers in Cellular and Infection Microbiology
- Type 2 diabetes susceptibility gene variants predispose to adult-onset autoimmune diabetes
- (2014) Mette K. Andersen et al. DIABETOLOGIA
- Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
- (2014) Anubha Mahajan et al. NATURE GENETICS
- Genetic loss of SH2B3 in acute lymphoblastic leukemia
- (2013) A. Perez-Garcia et al. BLOOD
- Islet infiltration, cytokine expression and beta cell death in the NOD mouse, BB rat, Komeda rat, LEW.1AR1-iddm rat and humans with type 1 diabetes
- (2013) Anne Jörns et al. DIABETOLOGIA
- The many faces of diabetes: a disease with increasing heterogeneity
- (2013) Tiinamaija Tuomi et al. LANCET
- Diabetes: a 21st century challenge
- (2013) Paul Z Zimmet et al. Lancet Diabetes & Endocrinology
- Adipose Tissue TCF7L2 Splicing Is Regulated by Weight Loss and Associates With Glucose and Fatty Acid Metabolism
- (2012) D. Kaminska et al. DIABETES
- Frequency, Immunogenetics, and Clinical Characteristics of Latent Autoimmune Diabetes in China (LADA China Study): A Nationwide, Multicenter, Clinic-Based Cross-Sectional Study
- (2012) Z. Zhou et al. DIABETES
- Association of PTPN22 C1858T Polymorphism and Type 1 Diabetes: A Meta-analysis
- (2012) Hui Peng et al. IMMUNOLOGICAL INVESTIGATIONS
- Targeted Overexpression of Inducible 6-Phosphofructo-2-kinase in Adipose Tissue Increases Fat Deposition but Protects against Diet-induced Insulin Resistance and Inflammatory Responses
- (2012) Yuqing Huo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The adaptor Lnk (SH2B3): An emerging regulator in vascular cells and a link between immune and inflammatory signaling
- (2011) Julie Devallière et al. BIOCHEMICAL PHARMACOLOGY
- The −1123G>C Variant of PTPN22 Gene Promoter is Associated with Latent Autoimmune Diabetes in Adult Chinese Hans
- (2011) Fang Liu et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- The type 2 diabetes-associated variant in TCF7L2 is associated with latent autoimmune diabetes in adult Europeans and the gene effect is modified by obesity: a meta-analysis and an individual study
- (2011) K. Lukacs et al. DIABETOLOGIA
- A Genome-Wide Meta-Analysis of Six Type 1 Diabetes Cohorts Identifies Multiple Associated Loci
- (2011) Jonathan P. Bradfield et al. PLoS Genetics
- Latent Autoimmune Diabetes in Adults Differs Genetically From Classical Type 1 Diabetes Diagnosed After the Age of 35 Years
- (2010) M. K. Andersen et al. DIABETES CARE
- Association of TCF7L2 gene variants with low GAD autoantibody titre in LADA subjects (NIRAD Study 5)
- (2010) S. Zampetti et al. DIABETIC MEDICINE
- A map of open chromatin in human pancreatic islets
- (2010) Kyle J Gaulton et al. NATURE GENETICS
- Type 2 Diabetes Susceptibility Gene Expression in Normal or Diabetic Sorted Human Alpha and Beta Cells: Correlations with Age or BMI of Islet Donors
- (2010) Clare L. Kirkpatrick et al. PLoS One
- Genetic Heterogeneity in Latent Autoimmune Diabetes Is Linked to Various Degrees of Autoimmune Activity: Results From the Nord-Trondelag Health Study
- (2009) E. Pettersen et al. DIABETES
- Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A
- (2009) J. M. M. Howson et al. DIABETES OBESITY & METABOLISM
- No association of multiple type 2 diabetes loci with type 1 diabetes
- (2009) S. M. Raj et al. DIABETOLOGIA
- Pfkfb3is transcriptionally upregulated in diabetic mouse liver through proliferative signals
- (2009) Joan Duran et al. FEBS Journal
- Disruption of Inducible 6-Phosphofructo-2-kinase Ameliorates Diet-induced Adiposity but Exacerbates Systemic Insulin Resistance and Adipose Tissue Inflammatory Response
- (2009) Yuqing Huo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
- (2009) Jeffrey C Barrett et al. NATURE GENETICS
- Genetic Similarities Between Latent Autoimmune Diabetes in Adults, Type 1 Diabetes, and Type 2 Diabetes
- (2008) C. Cervin et al. DIABETES
- Metabolic Syndrome and Autoimmune Diabetes: Action LADA 3
- (2008) M. I. Hawa et al. DIABETES CARE
- Glucagon-like Peptide-1 Activation of TCF7L2-dependent Wnt Signaling Enhances Pancreatic Beta Cell Proliferation
- (2008) Zhengyu Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Single Nucleotide Transcription Factor 7-Like 2 (TCF7L2) Gene Polymorphisms in Antiislet Autoantibody-Negative Patients at Onset of Diabetes
- (2008) Jeesuk Yu et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
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