标题
A New Therapeutic Framework for Atrial Fibrillation Drug Development
作者
关键词
-
出版物
CIRCULATION RESEARCH
Volume 127, Issue 1, Pages 184-201
出版商
Ovid Technologies (Wolters Kluwer Health)
发表日期
2020-06-19
DOI
10.1161/circresaha.120.316576
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Inflammatory cell infiltration in left atrial appendageal tissues of patients with atrial fibrillation and sinus rhythm
- (2020) Christopher Hohmann et al. Scientific Reports
- Challenges and Opportunities for Therapeutic Targeting of Calmodulin Kinase II in Heart
- (2020) Drew Nassal et al. Frontiers in Pharmacology
- Omecamtiv Mecarbil in Chronic Heart Failure With Reduced Ejection Fraction
- (2020) John R. Teerlink et al. JACC-Heart Failure
- Multispecific drugs herald a new era of biopharmaceutical innovation
- (2020) Raymond J. Deshaies NATURE
- Characterization, Pathogenesis, and Clinical Implications of Inflammation‐Related Atrial Myopathy as an Important Cause of Atrial Fibrillation
- (2020) Milton Packer Journal of the American Heart Association
- Anti-Inflammatory Therapy with Canakinumab for the Prevention of Hospitalization for Heart Failure
- (2019) Brendan M. Everett et al. CIRCULATION
- Tissue Resident CCR2− and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury
- (2019) Geetika Bajpai et al. CIRCULATION RESEARCH
- 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
- (2019) Craig T. January et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Advances in the Genetic Basis and Pathogenesis of Sarcomere Cardiomyopathies
- (2019) Raquel Yotti et al. Annual Review of Genomics and Human Genetics
- Cardiac Calcitropes, Myotropes, and Mitotropes
- (2019) Mitchell A. Psotka et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Cardiac glial cells release neurotrophic S100B upon catheter-based treatment of atrial fibrillation
- (2019) Katharina Scherschel et al. Science Translational Medicine
- Single-cell expression profiling reveals dynamic flux of cardiac stromal, vascular and immune cells in health and injury
- (2019) Nona Farbehi et al. eLife
- Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation
- (2019) Katherina M. Alsina et al. CIRCULATION
- Fatty acid conjugation enhances potency of antisense oligonucleotides in muscle
- (2019) Thazha P Prakash et al. NUCLEIC ACIDS RESEARCH
- Role of Big Data in Cardiovascular Research
- (2019) William S. Weintraub Journal of the American Heart Association
- Monogenic and Polygenic Contributions to Atrial Fibrillation Risk: Results from a National Biobank
- (2019) Seung Hoan Choi et al. CIRCULATION RESEARCH
- Atrial fibrillation and cardiac fibrosis
- (2019) Christian Sohns et al. EUROPEAN HEART JOURNAL
- Impact of atrial fibrillation/flutter on the in-hospital mortality of ischemic stroke patients
- (2019) Karsten Keller et al. HEART RHYTHM
- EZH2 as a novel therapeutic target for atrial fibrosis and atrial fibrillation
- (2019) Shuai Song et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Mass Spectrometry-Based Plasma Proteomics: Considerations from Sample Collection to Achieving Translational Data
- (2019) Vera Ignjatovic et al. JOURNAL OF PROTEOME RESEARCH
- Early sarcomere and metabolic defects in a zebrafish pitx2c cardiac arrhythmia model
- (2019) Michelle M. Collins et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacological Inhibitors of the NLRP3 Inflammasome
- (2019) Ayesha Zahid et al. Frontiers in Immunology
- Macrophage migration inhibitory factor increases atrial arrhythmogenesis through CD74 signaling
- (2019) Wan-Li Cheng et al. Translational Research
- Genome-wide Study of Atrial Fibrillation Identifies Seven Risk Loci and Highlights Biological Pathways and Regulatory Elements Involved in Cardiac Development
- (2018) Jonas B. Nielsen et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Enhanced Cardiomyocyte NLRP3 Inflammasome Signaling Promotes Atrial Fibrillation
- (2018) Chunxia Yao et al. CIRCULATION
- Stress Signaling JNK2 Crosstalk With CaMKII Underlies Enhanced Atrial ArrhythmogenesisNovelty and Significance
- (2018) Jiajie Yan et al. CIRCULATION RESEARCH
- Translational Challenges in Atrial Fibrillation
- (2018) Jordi Heijman et al. CIRCULATION RESEARCH
- The Transcription Factor ETV1 Induces Atrial Remodeling and Arrhythmia
- (2018) Carolin Rommel et al. CIRCULATION RESEARCH
- Multi-ethnic genome-wide association study for atrial fibrillation
- (2018) Carolina Roselli et al. NATURE GENETICS
- The human heart contains distinct macrophage subsets with divergent origins and functions
- (2018) Geetika Bajpai et al. NATURE MEDICINE
- Catheter Ablation for Atrial Fibrillation with Heart Failure
- (2018) Nassir F. Marrouche et al. NEW ENGLAND JOURNAL OF MEDICINE
- GalNAc-siRNA Conjugates: Leading the Way for Delivery of RNAi Therapeutics
- (2018) Aaron D. Springer et al. Nucleic Acid Therapeutics
- Single-Cell Deconvolution of Fibroblast Heterogeneity in Mouse Pulmonary Fibrosis
- (2018) Ting Xie et al. Cell Reports
- Fatty Infiltration of the Myocardium and Arrhythmogenesis: Potential Cellular and Molecular Mechanisms
- (2018) Justus M. B. Anumonwo et al. Frontiers in Physiology
- NLRP3: A Novel Mediator in Cardiovascular Disease
- (2018) Wenyi Zhou et al. Journal of Immunology Research
- Association of of Atrial Fibrillation Clinical Phenotypes With Treatment Patterns and Outcomes
- (2018) Taku Inohara et al. JAMA Cardiology
- Absence of NPR-C Attenuates TGF-ß1 Induced Selective Atrial Fibrosis and Atrial Fibrillation
- (2018) Dolkun Rahmutula et al. CARDIOVASCULAR RESEARCH
- Incident Atrial Fibrillation Is Associated With MYH7 Sarcomeric Gene Variation in Hypertrophic Cardiomyopathy
- (2018) Seung-Pyo Lee et al. Circulation-Heart Failure
- Biobank-driven genomic discovery yields new insight into atrial fibrillation biology
- (2018) Jonas B. Nielsen et al. NATURE GENETICS
- Fully Automated Echocardiogram Interpretation in Clinical Practice
- (2018) Jeffrey Zhang et al. CIRCULATION
- Modernized Classification of Cardiac Antiarrhythmic Drugs
- (2018) Ming Lei et al. CIRCULATION
- Long-term suppression of atrial fibrillation by botulinum toxin injection into epicardial fat pads in patients undergoing cardiac surgery: Three-year follow-up of a randomized study
- (2018) Alexander Romanov et al. HEART RHYTHM
- Role of autonomic nervous system in atrial fibrillation
- (2018) Dominik Linz et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- The Macrophage in Cardiac Homeostasis and Disease
- (2018) Kory J. Lavine et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Ion channels as therapeutic antibody targets
- (2018) Catherine J. Hutchings et al. mAbs
- Rare truncating variants in the sarcomeric protein titin associate with familial and early-onset atrial fibrillation
- (2018) Gustav Ahlberg et al. Nature Communications
- Neurokinin-3 receptor activation selectively prolongs atrial refractoriness by inhibition of a background K+ channel
- (2018) Marieke W. Veldkamp et al. Nature Communications
- Atrial Fibrosis by Late Gadolinium Enhancement Magnetic Resonance Imaging and Catheter Ablation of Atrial Fibrillation: 5‐Year Follow‐Up Data
- (2018) Mihail G. Chelu et al. Journal of the American Heart Association
- Regulatory Networks Involving STATs, IRFs, and NFκB in Inflammation
- (2018) Ekaterini Platanitis et al. Frontiers in Immunology
- EHRA/HRS/APHRS/SOLAECE expert consensus on atrial cardiomyopathies: Definition, characterization, and clinical implication
- (2017) Andreas Goette et al. HEART RHYTHM
- Mechanisms and Therapeutic Relevance of Neuro-immune Communication
- (2017) Sangeeta S. Chavan et al. IMMUNITY
- Ganglionated plexi as neuromodulation targets for atrial fibrillation
- (2017) Eue-Keun Choi et al. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
- CaMKII is a nodal signal for multiple programmed cell death pathways in heart
- (2017) Ning Feng et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Improving Atrial Fibrillation Therapy
- (2017) William J. Hucker et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Obesity and Atrial Fibrillation Prevalence, Pathogenesis, and Prognosis
- (2017) Carl J. Lavie et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- A Missense Variant in PLEC Increases Risk of Atrial Fibrillation
- (2017) Rosa B. Thorolfsdottir et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease
- (2017) Siddhartha Jaiswal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Atrial natriuretic peptide regulates adipose tissue accumulation in adult atria
- (2017) Nadine Suffee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Heritability of Atrial FibrillationCLINICAL PERSPECTIVE
- (2017) Lu-Chen Weng et al. Circulation-Cardiovascular Genetics
- Atrial remodelling in atrial fibrillation: CaMKII as a nodal proarrhythmic signal
- (2016) Olurotimi O. Mesubi et al. CARDIOVASCULAR RESEARCH
- Common variation in atrial fibrillation: navigating the path from genetic association to mechanism
- (2016) Nathan R. Tucker et al. CARDIOVASCULAR RESEARCH
- Clinical Characteristics and Outcomes in Extreme Elderly (Age ≥ 85 Years) Japanese Patients With Atrial Fibrillation
- (2016) Yugo Yamashita et al. CHEST
- Constitutive Expression of a Dominant-Negative TGF-β Type II Receptor in the Posterior Left Atrium Leads to Beneficial Remodeling of Atrial Fibrillation SubstrateNovelty and Significance
- (2016) Aaron Kunamalla et al. CIRCULATION RESEARCH
- Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation
- (2016) Henri M.H. Spronk et al. EUROPEAN HEART JOURNAL
- Catheter ablation in patients with persistent atrial fibrillation
- (2016) Paulus Kirchhof et al. EUROPEAN HEART JOURNAL
- 2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
- (2016) Paulus Kirchhof et al. EUROPEAN HEART JOURNAL
- A frameshift deletion in the sarcomere geneMYL4causes early-onset familial atrial fibrillation
- (2016) Daniel F. Gudbjartsson et al. EUROPEAN HEART JOURNAL
- Left atrial strain: A useful index in atrial fibrillation
- (2016) Matteo Cameli et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Development of antibody-siRNA conjugate targeted to cardiac and skeletal muscles
- (2016) Tsukasa Sugo et al. JOURNAL OF CONTROLLED RELEASE
- Clinical neurocardiology defining the value of neuroscience-based cardiovascular therapeutics
- (2016) Kalyanam Shivkumar et al. JOURNAL OF PHYSIOLOGY-LONDON
- Electrophysiological and molecular mechanisms of paroxysmal atrial fibrillation
- (2016) Stanley Nattel et al. Nature Reviews Cardiology
- Precision medicine in cardiology
- (2016) Elliott M. Antman et al. Nature Reviews Cardiology
- Arrhythmogenic cardiomyopathy
- (2016) Kalliopi Pilichou et al. Orphanet Journal of Rare Diseases
- Pitx2 modulates a Tbx5 -dependent gene regulatory network to maintain atrial rhythm
- (2016) Rangarajan D. Nadadur et al. Science Translational Medicine
- Atrial arrhythmogenesis in obstructive sleep apnea: Therapeutic implications
- (2016) Dominik Linz et al. SLEEP MEDICINE REVIEWS
- Antiarrhythmic Drug Therapy for Atrial Fibrillation
- (2016) Muhammad Rizwan Sardar et al. Heart Failure Clinics
- Chasing cardiac physiology and pathology down the CaMKII cascade
- (2015) Alicia Mattiazzi et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- The role of obesity in atrial fibrillation
- (2015) Chrishan Joseph Nalliah et al. EUROPEAN HEART JOURNAL
- Fibrotic Atrial Cardiomyopathy, Atrial Fibrillation, and Thromboembolism
- (2015) Benjamin J. Hirsh et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Inflammasomes: mechanism of action, role in disease and therapeutics
- (2015) Haitao Guo et al. NATURE MEDICINE
- Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment
- (2015) Larissa Fabritz et al. Nature Reviews Cardiology
- Comorbidity of atrial fibrillation and heart failure
- (2015) Liang-Han Ling et al. Nature Reviews Cardiology
- Inflammation and the pathogenesis of atrial fibrillation
- (2015) Yu-Feng Hu et al. Nature Reviews Cardiology
- Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFα
- (2015) Roozbeh Aschar-Sobbi et al. Nature Communications
- Atrial Fibrillation Therapy Now and in the Future
- (2014) Christopher E. Woods et al. CIRCULATION RESEARCH
- Role of the Autonomic Nervous System in Atrial Fibrillation
- (2014) Peng-Sheng Chen et al. CIRCULATION RESEARCH
- Clinical Classifications of Atrial Fibrillation Poorly Reflect Its Temporal Persistence
- (2014) Efstratios I. Charitos et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation
- (2014) Craig T. January et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Single-cell technologies for monitoring immune systems
- (2014) Pratip K Chattopadhyay et al. NATURE IMMUNOLOGY
- CaMKII inhibitors: from research tools to therapeutic agents
- (2014) Patricia Pellicena et al. Frontiers in Pharmacology
- Molecular basis of selective atrial fibrosis due to overexpression of transforming growth factor-β1
- (2013) Dolkun Rahmutula et al. CARDIOVASCULAR RESEARCH
- Worldwide Epidemiology of Atrial Fibrillation
- (2013) Sumeet S. Chugh et al. CIRCULATION
- Protein Engineering for Cardiovascular Therapeutics
- (2013) Steven M. Jay et al. CIRCULATION RESEARCH
- Atrial Fibrillation Ablation Outcome Is Predicted by Left Atrial Remodeling on MRI
- (2013) Christopher McGann et al. Circulation-Arrhythmia and Electrophysiology
- Personalized management of atrial fibrillation: Proceedings from the fourth Atrial Fibrillation competence NETwork/European Heart Rhythm Association consensus conference
- (2013) P. Kirchhof et al. EUROPACE
- Atrial fibrillation: the role of common and rare genetic variants
- (2013) Morten S Olesen et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Effect of Sleep Apnea and Continuous Positive Airway Pressure on Cardiac Structure and Recurrence of Atrial Fibrillation
- (2013) Tomas G. Neilan et al. Journal of the American Heart Association
- Adipocytes modulate the electrophysiology of atrial myocytes: implications in obesity-induced atrial fibrillation
- (2012) Yung-Kuo Lin et al. BASIC RESEARCH IN CARDIOLOGY
- Left Atrial Anatomy Revisited
- (2012) Siew Yen Ho et al. Circulation-Arrhythmia and Electrophysiology
- Inflammation in Atrial Fibrillation
- (2012) Yutao Guo et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Assessment of Left Atrial Deformation and Synchrony by Three-Dimensional Speckle-Tracking Echocardiography: Comparative Studies in Healthy Subjects and Patients with Atrial Fibrillation
- (2012) Atsushi Mochizuki et al. JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY
- Angiotensin II-Antagonist in Paroxysmal Atrial Fibrillation (ANTIPAF) Trial
- (2011) Andreas Goette et al. Circulation-Arrhythmia and Electrophysiology
- Upstream therapies for management of atrial fibrillation: review of clinical evidence and implications for European Society of Cardiology guidelines. Part II: secondary prevention
- (2011) I. Savelieva et al. EUROPACE
- Total and Interatrial Epicardial Adipose Tissues Are Independently Associated With Left Atrial Remodeling in Patients With Atrial Fibrillation
- (2011) SEUNG YONG SHIN et al. JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
- Pathophysiological Mechanisms of Atrial Fibrillation: A Translational Appraisal
- (2011) Ulrich Schotten et al. PHYSIOLOGICAL REVIEWS
- Intrinsic Cardiac Nerve Activity and Paroxysmal Atrial Tachyarrhythmia in Ambulatory Dogs
- (2010) Eue-Keun Choi et al. CIRCULATION
- CCR2 Antagonists
- (2010) Mary Struthers et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Sinus rhythm is associated with fewer heart failure symptoms: Insights from the AFFIRM trial
- (2010) Maya Guglin et al. HEART RHYTHM
- Progression From Paroxysmal to Persistent Atrial Fibrillation
- (2010) Cees B. de Vos et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Effects of istaroxime on diastolic stiffness in acute heart failure syndromes: Results from the Hemodynamic, Echocardiographic, and Neurohormonal Effects of Istaroxime, a Novel Intravenous Inotropic and Lusitropic Agent: a Randomized Controlled Trial in Patients Hospitalized with Heart Failure (HORIZON-HF) trial
- (2009) Sanjiv J. Shah et al. AMERICAN HEART JOURNAL
- Valsartan for Prevention of Recurrent Atrial Fibrillation
- (2009) NEW ENGLAND JOURNAL OF MEDICINE
- Differential Behaviors of Atrial Versus Ventricular Fibroblasts
- (2008) Brett Burstein et al. CIRCULATION
- Endurance sport practice as a risk factor for atrial fibrillation and atrial flutter
- (2008) L. Mont et al. EUROPACE
- Prognostic role of pro- and anti-inflammatory cytokines and their polymorphisms in acute decompensated heart failure
- (2008) Kati H. Miettinen et al. EUROPEAN JOURNAL OF HEART FAILURE
- Potential clinical relevance of the ‘little brain’ on the mammalian heart
- (2007) J. A. Armour EXPERIMENTAL PHYSIOLOGY
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