Nuclear morphologies: their diversity and functional relevance

Why are Neutrophils Polymorphonuclear?

(2017) P. Veda   European Journal of Inflammation

Cellular lifespan and senescence: a complex balance between multiple cellular pathways

(2016) David Dolivo et al.   BIOESSAYS

Non-random chromosome arrangement in triploid endosperm nuclei

(2016) Célia Baroux et al.   CHROMOSOMA

Squish and squeeze — the nucleus as a physical barrier during migration in confined environments

(2016) Alexandra Lynn McGregor et al.   CURRENT OPINION IN CELL BIOLOGY

A model for coordinating nuclear mechanics and membrane remodeling to support nuclear integrity

(2016) Megan C King et al.   CURRENT OPINION IN CELL BIOLOGY

From single genes to entire genomes: the search for a function of nuclear organization

(2016) Ringo Pueschel et al.   DEVELOPMENT

Nuclear size measurement for distinguishing urothelial carcinomas from reactive urothelium on tissue sections

(2016) Kate Poropatich et al.   Diagnostic Pathology

Causes and consequences of nuclear envelope alterations in tumour progression

(2016) Emily S. Bell et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Molecular insights into the premature aging disease progeria

(2016) Sandra Vidak et al.   HISTOCHEMISTRY AND CELL BIOLOGY

ESCRT III repairs nuclear envelope ruptures during cell migration to limit DNA damage and cell death

(2016) M. Raab et al.   SCIENCE

Nuclear envelope rupture and repair during cancer cell migration

(2016) C. M. Denais et al.   SCIENCE

The anticancer effect of chaetocin is enhanced by inhibition of autophagy

(2016) H-J Jung et al.   Cell Death & Disease

Actin nucleation at the centrosome controls lymphocyte polarity

(2016) Dorian Obino et al.   Nature Communications

Anchoring a Leviathan: How the Nuclear Membrane Tethers the Genome

(2016) Rafal Czapiewski et al.   Frontiers in Genetics

Defining cell types and states with single-cell genomics

(2015) Cole Trapnell   GENOME RESEARCH

Teratozoospermia: spotlight on the main genetic actors in the human

(2015) C. Coutton et al.   HUMAN REPRODUCTION UPDATE

Micropatterned Macrophage Analysis Reveals Global Cytoskeleton Constraints Induced by Bacillus anthracis Edema Toxin

(2015) Yannick Trescos et al.   INFECTION AND IMMUNITY

Genetic aspects of monomorphic teratozoospermia: a review

(2015) Marc De Braekeleer et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Accessorizing and anchoring the LINC complex for multifunctionality

(2015) Wakam Chang et al.   JOURNAL OF CELL BIOLOGY

Novel mutations in the PNPLA6 gene in Boucher-Neuhäuser syndrome

(2015) Kishin Koh et al.   JOURNAL OF HUMAN GENETICS

Cytoskeletal Control of Nuclear Morphology and Chromatin Organization

(2015) Nisha M. Ramdas et al.   JOURNAL OF MOLECULAR BIOLOGY

Quantitative analysis of nuclear shape in oral squamous cell carcinoma is useful for predicting the chemotherapeutic response

(2015) Maki Ogura et al.   Medical Molecular Morphology

Lipid partitioning at the nuclear envelope controls membrane biogenesis

(2015) Antonio Daniel Barbosa et al.   MOLECULAR BIOLOGY OF THE CELL

ESCRT-III controls nuclear envelope reformation

(2015) Yolanda Olmos et al.   NATURE

Remodeling of the Nuclear Envelope and Lamina during Bovine Preimplantation Development and Its Functional Implications

(2015) Jens Popken et al.   PLoS One

Remodeling of nuclear landscapes during human myelopoietic cell differentiation maintains co-aligned active and inactive nuclear compartments

(2015) Barbara Hübner et al.   Epigenetics & Chromatin

The tethering of chromatin to the nuclear envelope supports nuclear mechanics

(2015) Sarah M. Schreiner et al.   Nature Communications

The SUV39H1 inhibitor chaetocin induces differentiation and shows synergistic cytotoxicity with other epigenetic drugs in acute myeloid leukemia cells

(2015) Y-S Lai et al.   Blood Cancer Journal

Bridging the Gap: From 2D Cell Culture to 3D Microengineered Extracellular Matrices

(2015) Yanfen Li et al.   Advanced Healthcare Materials

Global Reorganization of the Nuclear Landscape in Senescent Cells

(2015) Tamir Chandra et al.   Cell Reports

Subspecific variation in sperm morphology and performance in the Long-tailed Finch (Poephila acuticauda)

(2015) Melissah Rowe et al.   Avian Research

Nuclear hypersegmentation of neutrophils, eosinophils, and basophils due to hydroxycarbamide (hydroxyurea)

(2014) X. Xu   BLOOD

Direct visualization of the endomitotic cell cycle in living megakaryocytes: Differential patterns in low and high ploidy cells

(2014) Nicholas Papadantonakis et al.   CELL CYCLE

Matrix Elasticity Regulates Lamin-A,C Phosphorylation and Turnover with Feedback to Actomyosin

(2014) Amnon Buxboim et al.   CURRENT BIOLOGY

Geometry of the nucleus: a perspective on gene expression regulation

(2014) Maxime Woringer et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival

(2014) Takamasa Harada et al.   JOURNAL OF CELL BIOLOGY

Auxetic nuclei in embryonic stem cells exiting pluripotency

(2014) Stefano Pagliara et al.   NATURE MATERIALS

Physical constraints determine the logic of bacterial promoter architectures

(2014) Daphne Ezer et al.   NUCLEIC ACIDS RESEARCH

Direct observation of light focusing by single photoreceptor cell nuclei

(2014) Zuzanna Błaszczak et al.   OPTICS EXPRESS

Microtubules and spermatogenesis

(2014) Liza O’Donnell et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Tracking the Elusive Fibrocyte: Identification and Characterization of Collagen-Producing Hematopoietic Lineage Cells During Murine Wound Healing

(2014) Hirotaka Suga et al.   STEM CELLS

Reprogramming of fibroblast nuclei in cloned bovine embryos involves major structural remodeling with both striking similarities and differences to nuclear phenotypes ofin vitrofertilized embryos

(2014) Jens Popken et al.   Nucleus

Chromatin dynamics during spermiogenesis

(2013) Christina Rathke et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

3D organization of telomeres in porcine neutrophils and analysis of LPS-activation effect

(2013) Florence Mompart et al.   BMC CELL BIOLOGY

PNPLA6 mutations cause Boucher-Neuhäuser and Gordon Holmes syndromes as part of a broad neurodegenerative spectrum

(2013) Matthis Synofzik et al.   BRAIN

Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System

(2013) Baohui Chen et al.   CELL

Genome Architecture: Domain Organization of Interphase Chromosomes

(2013) Wendy A. Bickmore et al.   CELL

Nesprins: from the nuclear envelope and beyond

(2013) Dipen Rajgor et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The incredible journey: From megakaryocyte development to platelet formation

(2013) Kellie R. Machlus et al.   JOURNAL OF CELL BIOLOGY

Ultrastructure of spermatogenesis in the short-tailed fruit bat,Carollia perspicillata(Chiroptera: Phyllostomidae: Carollinae)

(2013) Mateus R Beguelini et al.   JOURNAL OF MORPHOLOGY

Effect of nuclear architecture on the efficiency of double-strand break repair

(2013) Neta Agmon et al.   NATURE CELL BIOLOGY

Nuclear Shape Changes Are Induced by Knockdown of the SWI/SNF ATPase BRG1 and Are Independent of Cytoskeletal Connections

(2013) Karen M. Imbalzano et al.   PLoS One

Activated T Cell Trans-Endothelial Migration Relies on Myosin-IIA Contractility for Squeezing the Cell Nucleus through Endothelial Cell Barriers

(2013) Jordan Jacobelli et al.   PLoS One

Reduced Number and Morphofunctional Change of Alveolar Macrophages in MafB Gene-Targeted Mice

(2013) Michiko Sato-Nishiwaki et al.   PLoS One

Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells

(2013) J.-W. Shin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical model of blebbing in nuclear lamin meshworks

(2013) Chloe M. Funkhouser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell geometric constraints induce modular gene-expression patterns via redistribution of HDAC3 regulated by actomyosin contractility

(2013) N. Jain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

(2013) J. Swift et al.   SCIENCE

Organization of the Mitotic Chromosome

(2013) N. Naumova et al.   SCIENCE

Cell confinement: putting the squeeze on the nucleus

(2013) Marie Versaevel et al.   Soft Matter

The expanding world of extracellular traps: not only neutrophils but much more

(2013) Oliver Goldmann et al.   Frontiers in Immunology

Cytotoxic T lymphocyte effector function is independent of nucleus-centrosome dissociation

(2012) Winnie W. Y. Lui-Roberts et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neutrophil extracellular traps: Is immunity the second function of chromatin?

(2012) Volker Brinkmann et al.   JOURNAL OF CELL BIOLOGY

The role of microtubules in neutrophil polarity and migration in live zebrafish

(2012) S. K. Yoo et al.   JOURNAL OF CELL SCIENCE

Independence of Repressive Histone Marks and Chromatin Compaction during Senescent Heterochromatic Layer Formation

(2012) Tamir Chandra et al.   MOLECULAR CELL

Role of Actin Dependent Nuclear Deformation in Regulating Early Gene Expression

(2012) Soumya Gupta et al.   PLoS One

Sperm wars and the evolution of male fertility

(2012) Leigh W Simmons et al.   REPRODUCTION

Nuclear Actin and Lamins in Viral Infections

(2012) Jakub Cibulka et al.   Viruses-Basel

Spatial coordination between cell and nuclear shape within micropatterned endothelial cells

(2012) Marie Versaevel et al.   Nature Communications

A Genetic Basis for a Postmeiotic X Versus Y Chromosome Intragenomic Conflict in the Mouse

(2012) Julie Cocquet et al.   PLoS Genetics

Sperm structure and motility in the eusocial naked mole-rat, Heterocephalus glaber: a case of degenerative orthogenesis in the absence of sperm competition?

(2011) Gerhard van der Horst et al.   BMC EVOLUTIONARY BIOLOGY

Internuclear chromosome distribution of dysplastic megakaryocytes in myelodysplastic syndromes is dependent on the level of ploidy

(2011) Claudia Münch et al.   CHROMOSOMA

Stress fibers stabilize the position of intranuclear DNA through mechanical connection with the nucleus in vascular smooth muscle cells

(2011) Kazuaki Nagayama et al.   FEBS LETTERS

Lipin Is a Central Regulator of Adipose Tissue Development and Function in Drosophila melanogaster

(2011) R. Ugrankar et al.   MOLECULAR AND CELLULAR BIOLOGY

Determinants of nucleosome organization in primary human cells

(2011) Anton Valouev et al.   NATURE

Scrotal insulation and its relationship to abnormal morphology, chromatin protamination and nuclear shape of spermatozoa in Holstein-Friesian and Belgian Blue bulls

(2011) Mohammad Bozlur Rahman et al.   THERIOGENOLOGY

Determining nuclear shape: The role of farnesylated nuclear membrane proteins

(2011) Maria Polychronidou et al.   Nucleus

Leukocyte Nucleus Segmentation and Nucleus Lobe Counting

(2010) Yung-Kuan Chan et al.   BMC BIOINFORMATICS

Human fetal/tumor metakaryotic stem cells: pangenomic homologous pairing and telomeric end-joining of chromatids

(2010) Amanda N. Gruhl et al.   CANCER GENETICS AND CYTOGENETICS

A Human iPSC Model of Hutchinson Gilford Progeria Reveals Vascular Smooth Muscle and Mesenchymal Stem Cell Defects

(2010) Jinqiu Zhang et al.   Cell Stem Cell

Remodeling of nuclear architecture by the thiodioxoxpiperazine metabolite chaetocin

(2010) Doris Illner et al.   EXPERIMENTAL CELL RESEARCH

Tissue stretch induces nuclear remodeling in connective tissue fibroblasts

(2010) Helene M. Langevin et al.   HISTOCHEMISTRY AND CELL BIOLOGY

A Novel Mechanism of Rapid Nuclear Neutrophil Extracellular Trap Formation in Response to Staphylococcus aureus

(2010) F. H. Pilsczek et al.   JOURNAL OF IMMUNOLOGY

Actomyosin Contraction at the Cell Rear Drives Nuclear Translocation in Migrating Cortical Interneurons

(2010) F. J. Martini et al.   JOURNAL OF NEUROSCIENCE

Are hypersegmented neutrophils a characteristic of Boucher–Neuhäuser syndrome?

(2010) Tadashi Umehara et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Progeria syndromes and ageing: what is the connection?

(2010) Christopher R. Burtner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct Types of Fibrocyte Can Differentiate from Mononuclear Cells in the Presence and Absence of Serum

(2010) S. John Curnow et al.   PLoS One

Calpain modulates capacitation and acrosome reaction through cleavage of the spectrin cytoskeleton

(2010) Yadira Bastián et al.   REPRODUCTION

Neutrophil kinetics in health and disease

(2010) Charlotte Summers et al.   TRENDS IN IMMUNOLOGY

Chromosome Territories

(2010) T. Cremer et al.   Cold Spring Harbor Perspectives in Biology

Metakaryotic stem cell lineages in organogenesis of humans and other metazoans

(2010) Elena V. Gostjeva et al.   Organogenesis

Monocytes and Neutrophils Exhibit Both Distinct and Common Mechanisms in Penetrating the Vascular Basement Membrane In Vivo

(2009) Mathieu-Benoît Voisin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nuclear Architecture of Rod Photoreceptor Cells Adapts to Vision in Mammalian Evolution

(2009) Irina Solovei et al.   CELL

Dynein is a motor for nuclear rotation while vimentin IFs is a “brake”

(2009) Maxim V. Gerashchenko et al.   CELL BIOLOGY INTERNATIONAL

Nuclear architecture of resting and LPS-stimulated porcine neutrophils by 3D FISH

(2009) Martine Yerle-Bouissou et al.   CHROMOSOME RESEARCH

Changes of higher order chromatin arrangements during major genome activation in bovine preimplantation embryos

(2009) Daniela Koehler et al.   EXPERIMENTAL CELL RESEARCH

Sizing up the nucleus: nuclear shape, size and nuclear-envelope assembly

(2009) M. Webster et al.   JOURNAL OF CELL SCIENCE

Comparative Morphology, Development, and Function of Blood Cells in Nonmammalian Vertebrates

(2009) Juan A. Claver et al.   Journal of Exotic Pet Medicine

Hydrodynamic propulsion of human sperm

(2009) ERIC A. GILLIES et al.   JOURNAL OF FLUID MECHANICS

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

Implications of diversity in sperm size and function for sperm competition and fertility

(2008) Montserrat Gomendio et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Locus-specific and activity-independent gene repositioning during early tumorigenesis

(2008) Karen J. Meaburn et al.   JOURNAL OF CELL BIOLOGY

Change in cell shape is required for matrix metalloproteinase-induced epithelial-mesenchymal transition of mammary epithelial cells

(2008) Celeste M. Nelson et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

An automated image analysis methodology for classifying megakaryocytes in chronic myeloproliferative disorders

(2008) Benedetto Ballarò et al.   MEDICAL IMAGE ANALYSIS

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE

Modulation of Stem Cell Shape and Fate A: The Role of Density and Seeding Protocol on Nucleus Shape and Gene Expression

(2008) Sara H. McBride et al.   TISSUE ENGINEERING PART A

Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells

(2008) Lee E. Finlan et al.   PLoS Genetics