The lncRNA H19 binding to let‐7b promotes hippocampal glial cell activation and epileptic seizures by targeting Stat3 in a rat model of temporal lobe epilepsy

Long noncoding RNA HOST2, working as a competitive endogenous RNA, promotes STAT3-mediated cell proliferation and migration via decoying of let-7b in triple-negative breast cancer

(2020) Kaiyao Hua et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cerebrospinal fluid CD4+ T lymphocyte-derived miRNA-let-7b can enhances the diagnostic performance of Alzheimer's disease biomarkers

(2018) Yaping Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy

(2018) Chun-Lei Han et al.   Journal of Neuroinflammation

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

H19 facilitates tongue squamous cell carcinoma migration and invasion via sponging miR-let-7

(2018) Ni Kou et al.   ONCOLOGY RESEARCH

Long non-coding RNA H19 contributes to apoptosis of hippocampal neurons by inhibiting let-7b in a rat model of temporal lobe epilepsy

(2018) Chun-Lei Han et al.   Cell Death & Disease

Gene Expression Profiling of Two Epilepsy Models Reveals the ECM/Integrin signaling Pathway is Involved in Epiletogenesis

(2018) Chun-Lei Han et al.   NEUROSCIENCE

Extent of mossy fiber sprouting in patients with mesiotemporal lobe epilepsy correlates with neuronal cell loss and granule cell dispersion

(2017) Barbara Schmeiser et al.   EPILEPSY RESEARCH

Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy

(2017) Mootaz M. Salman et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Roles of microRNA let-7b in papillary thyroid carcinoma by regulating HMGA2

(2017) Hongguang Li et al.   TUMOR BIOLOGY

H19/let-7/LIN28 reciprocal negative regulatory circuit promotes breast cancer stem cell maintenance

(2017) Fei Peng et al.   Cell Death & Disease

Hypoxia induces H19 expression through direct and indirect Hif-1α activity, promoting oncogenic effects in glioblastoma

(2017) Weining Wu et al.   Scientific Reports

Let-7b inhibits the malignant behavior of glioma cells and glioma stem-like cells via downregulation of E2F2

(2016) Hang Song et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Postictal behavioural impairments are due to a severe prolonged hypoperfusion/hypoxia event that is COX-2 dependent

(2016) Jordan S Farrell et al.   eLife

MicroRNAs let-7b/i suppress human glioma cell invasion and migration by targeting IKBKE directly

(2015) Yuan Tian et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The lncRNA H19 promotes epithelial to mesenchymal transition by functioning as miRNA sponges in colorectal cancer

(2015) Wei-Cheng Liang et al.   Oncotarget

Genome-wide circulating microRNA expression profiling indicates biomarkers for epilepsy

(2015) Jun Wang et al.   Scientific Reports

let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3

(2015) Onju Ham et al.   Stem Cell Research & Therapy

The challenge and promise of anti-epileptic therapy development in animal models

(2014) Michele Simonato et al.   LANCET NEUROLOGY

The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells

(2014) Yuan Gao et al.   NUCLEIC ACIDS RESEARCH

Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation

(2014) L Yan et al.   ONCOGENE

Competing Endogenous RNA: The Key to Posttranscriptional Regulation

(2014) Rituparno Sen et al.   TheScientificWorldJOURNAL

Prognostic significance of let-7b expression in breast cancer and correlation to its target gene of BSG expression

(2013) Lin Ma et al.   MEDICAL ONCOLOGY

The Imprinted H19 LncRNA Antagonizes Let-7 MicroRNAs

(2013) Amanda N. Kallen et al.   MOLECULAR CELL

Changes in MicroRNA Expression in the Whole Hippocampus and Hippocampal Synaptoneurosome Fraction following Pilocarpine Induced Status Epilepticus

(2013) Rashmi M. Risbud et al.   PLoS One

On the classification of long non-coding RNAs

(2013) Lina Ma et al.   RNA Biology

Reduced Mature MicroRNA Levels in Association with Dicer Loss in Human Temporal Lobe Epilepsy with Hippocampal Sclerosis

(2012) Ross C. McKiernan et al.   PLoS One

Mapping the Spatio-Temporal Pattern of the Mammalian Target of Rapamycin (mTOR) Activation in Temporal Lobe Epilepsy

(2012) Long-Ze Sha et al.   PLoS One

JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats

(2011) Makoto Tsuda et al.   BRAIN

Temporal lobe epilepsy induces differential expression of hippocampal miRNAs including let-7e and miR-23a/b

(2011) Yi-jun Song et al.   BRAIN RESEARCH

A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

(2011) Leonardo Salmena et al.   CELL

Mechanisms of epileptogenesis and potential treatment targets

(2011) Asla Pitkänen et al.   LANCET NEUROLOGY

Role of Signal Transducer and Activator of Transcription-3 in Up-Regulation of GFAP After Epilepsy

(2011) Zucai Xu et al.   NEUROCHEMICAL RESEARCH

The oncofetal H19 RNA connection: Hypoxia, p53 and cancer

(2010) Imad J. Matouk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy

(2010) Xiaoxing Huang et al.   NEUROBIOLOGY OF DISEASE

Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line

(2010) Keiichi Ohshima et al.   PLoS One

MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling

(2010) C. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocyte dysfunction in epilepsy

(2009) Gerald Seifert et al.   BRAIN RESEARCH REVIEWS

The Mammalian Target of Rapamycin Signaling Pathway Mediates Epileptogenesis in a Model of Temporal Lobe Epilepsy

(2009) L.-H. Zeng et al.   JOURNAL OF NEUROSCIENCE

Status Epilepticus Induces a Particular Microglial Activation State Characterized by Enhanced Purinergic Signaling

(2008) E. Avignone et al.   JOURNAL OF NEUROSCIENCE

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE