Loss of Ryanodine Receptor 2 impairs neuronal activity-dependent remodeling of dendritic spines and triggers compensatory neuronal hyperexcitability

Uncovering a Role for the Dorsal Hippocampal Commissure in Recognition Memory

(2019) M Postans et al.   CEREBRAL CORTEX

Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease

(2019) Pooja Jadiya et al.   Nature Communications

Calcium Release Mediated by Redox-Sensitive RyR2 Channels Has a Central Role in Hippocampal Structural Plasticity and Spatial Memory

(2018) Jamileth Y. More et al.   ANTIOXIDANTS & REDOX SIGNALING

Automated gesture tracking in head-fixed mice

(2018) A. Giovannucci et al.   JOURNAL OF NEUROSCIENCE METHODS

Memory formation depends on both synapse-specific modifications of synaptic strength and cell-specific increases in excitability

(2018) John Lisman et al.   NATURE NEUROSCIENCE

The role of engram cells in the systems consolidation of memory

(2018) Susumu Tonegawa et al.   NATURE REVIEWS NEUROSCIENCE

Cocaine Place Conditioning Strengthens Location-Specific Hippocampal Coupling to the Nucleus Accumbens

(2018) Lucas Sjulson et al.   NEURON

Reward behaviour is regulated by the strength of hippocampus–nucleus accumbens synapses

(2018) Tara A. LeGates et al.   NATURE

Long-Term Potentiation Requires a Rapid Burst of Dendritic Mitochondrial Fission during Induction

(2018) Sai Sachin Divakaruni et al.   NEURON

Hippocampal Proteomic Analysis Reveals Distinct Pathway Deregulation Profiles at Early and Late Stages in a Rat Model of Alzheimer’s-Like Amyloid Pathology

(2017) Sonia Do Carmo et al.   MOLECULAR NEUROBIOLOGY

Double-Nanodomain Coupling of Calcium Channels, Ryanodine Receptors, and BK Channels Controls the Generation of Burst Firing

(2017) Tomohiko Irie et al.   NEURON

Tau Pathology Induces Excitatory Neuron Loss, Grid Cell Dysfunction, and Spatial Memory Deficits Reminiscent of Early Alzheimer’s Disease

(2017) Hongjun Fu et al.   NEURON

Input-dependent regulation of excitability controls dendritic maturation in somatosensory thalamocortical neurons

(2017) Laura Frangeul et al.   Nature Communications

Fast online deconvolution of calcium imaging data

(2017) Johannes Friedrich et al.   PLoS Computational Biology

Correlated Synaptic Inputs Drive Dendritic Calcium Amplification and Cooperative Plasticity during Clustered Synapse Development

(2016) Kevin F.H. Lee et al.   NEURON

Dysfunction of Somatostatin-Positive Interneurons Associated with Memory Deficits in an Alzheimer’s Disease Model

(2016) Lena C. Schmid et al.   NEURON

Interhemispheric microstructural connectivity in bitemporal lobe epilepsy with hippocampal sclerosis

(2015) Júlia Miró et al.   CORTEX

Ryanodine Receptors: Allosteric Ion Channel Giants

(2015) Filip Van Petegem   JOURNAL OF MOLECULAR BIOLOGY

Locomotion, Theta Oscillations, and the Speed-Correlated Firing of Hippocampal Neurons Are Controlled by a Medial Septal Glutamatergic Circuit

(2015) Falko Fuhrmann et al.   NEURON

Structural Components of Synaptic Plasticity and Memory Consolidation

(2015) Craig H. Bailey et al.   Cold Spring Harbor Perspectives in Biology

Ryanodine Receptor Activation Induces Long-Term Plasticity of Spine Calcium Dynamics

(2015) Friedrich W. Johenning et al.   PLOS BIOLOGY

Reduced dendritic arborization and hyperexcitability of pyramidal neurons in a Scn1b-based model of Dravet syndrome

(2014) Christopher A. Reid et al.   BRAIN

The role of ryanodine receptor type 3 in a mouse model of Alzheimer disease

(2014) Jie Liu et al.   Channels

Long-Term In Vivo Imaging of Dendritic Spines in the Hippocampus Reveals Structural Plasticity

(2014) L. Gu et al.   JOURNAL OF NEUROSCIENCE

Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease

(2014) Zuzana Šišková et al.   NEURON

Differential rescue of spatial memory deficits in aged rats by L-type voltage-dependent calcium channel and ryanodine receptor antagonism

(2014) S.C. Hopp et al.   NEUROSCIENCE

The influence of phospho-tau on dendritic spines of cortical pyramidal neurons in patients with Alzheimer’s disease

(2013) Paula Merino-Serrais et al.   BRAIN

The role of intracellular calcium stores in synaptic plasticity and memory consolidation

(2013) Kathryn D. Baker et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Role of Leaky Neuronal Ryanodine Receptors in Stress- Induced Cognitive Dysfunction

(2012) Xiaoping Liu et al.   CELL

Dendritic spines: from structure to in vivo function

(2012) Nathalie L Rochefort et al.   EMBO REPORTS

Ryanodine Receptors: Structure and Function

(2012) Filip Van Petegem   JOURNAL OF BIOLOGICAL CHEMISTRY

Altered dendritic complexity affects firing properties of cortical layer 2/3 pyramidal neurons in mice lacking the 5-HT3A receptor

(2012) Luuk van der Velden et al.   JOURNAL OF NEUROPHYSIOLOGY

Ryanodine Receptor Blockade Reduces Amyloid-  Load and Memory Impairments in Tg2576 Mouse Model of Alzheimer Disease

(2012) B. Oules et al.   JOURNAL OF NEUROSCIENCE

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

(2012) Michael J. Schmeisser et al.   NATURE

Reduction of Hippocampal Hyperactivity Improves Cognition in Amnestic Mild Cognitive Impairment

(2012) Arnold Bakker et al.   NEURON

Pharmacobehavioural evidence for nitric oxide and noradrenaline interactions with ryanodine receptors during memory formation in the young chick.

(2011) Kathryn D. Baker et al.   BEHAVIORAL NEUROSCIENCE

Nitric oxide-induced calcium release via ryanodine receptors regulates neuronal function

(2011) Sho Kakizawa et al.   EMBO JOURNAL

A perfect storm: Converging paths of epilepsy and Alzheimer’s dementia intersect in the hippocampal formation

(2011) Jeffrey Noebels   EPILEPSIA

Targeting of the Arpc3 actin nucleation factor by miR-29a/b regulates dendritic spine morphology

(2011) Giordano Lippi et al.   JOURNAL OF CELL BIOLOGY

Dopamine D1 Receptors Participate in Cocaine-Induced Place Preference via Regulation of Ryanodine Receptor Expression

(2011) Kazuhiro Kurokawa et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Glutamate induces de novo growth of functional spines in developing cortex

(2011) Hyung-Bae Kwon et al.   NATURE

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease

(2011) Angela M. Bruno et al.   NEUROBIOLOGY OF AGING

Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation

(2011) T. Adasme et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ryanodine receptor-2 upregulation and nicotine-mediated plasticity

(2010) Elena Ziviani et al.   EMBO JOURNAL

Regulation of ryanodine receptors by dopamine D1 receptors during methamphetamine-induced place conditioning

(2010) Kazuhiro Kurokawa et al.   JOURNAL OF NEUROCHEMISTRY

Functional imaging of hippocampal place cells at cellular resolution during virtual navigation

(2010) Daniel A Dombeck et al.   NATURE NEUROSCIENCE

Searching for Engrams

(2010) Mark Hübener et al.   NEURON

Ryanodine Receptors: Structure, Expression, Molecular Details, and Function in Calcium Release

(2010) J. T. Lanner et al.   Cold Spring Harbor Perspectives in Biology

A ryanodine receptor agonist promotes the consolidation of long-term memory in young chicks

(2009) Kathryn D. Baker et al.   BEHAVIOURAL BRAIN RESEARCH

Amyloid  -Induced Neuronal Hyperexcitability Triggers Progressive Epilepsy

(2009) R. Minkeviciene et al.   JOURNAL OF NEUROSCIENCE

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

(2009) Dong-Hyung Cho et al.   SCIENCE

A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice

(2008) Nicoletta Galeotti et al.   JOURNAL OF NEUROCHEMISTRY

Different involvement of type 1, 2, and 3 ryanodine receptors in memory processes

(2008) N. Galeotti et al.   LEARNING & MEMORY

Automated Three-Dimensional Detection and Shape Classification of Dendritic Spines from Fluorescence Microscopy Images

(2008) Alfredo Rodriguez et al.   PLoS One

Place cell firing correlates with memory deficits and amyloid plaque burden in Tg2576 Alzheimer mouse model

(2008) F. Cacucci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE

Critical role of type 2 ryanodine receptor in mediating activity-dependent neurogenesis from embryonic stem cells

(2007) Hui-Mei Yu et al.   CELL CALCIUM