Ryanodine Receptors: Structure and Function

Structural and functional conservation of key domains in InsP3 and ryanodine receptors

(2012) Min-Duk Seo et al.   NATURE

Disease Mutations in the Ryanodine Receptor Central Region: Crystal Structures of a Phosphorylation Hot Spot Domain

(2012) Zhiguang Yuchi et al.   STRUCTURE

S100A1 and calmodulin regulation of ryanodine receptor in striated muscle

(2011) Benjamin L. Prosser et al.   CELL CALCIUM

Ryanodine Receptor Oxidation Causes Intracellular Calcium Leak and Muscle Weakness in Aging

(2011) Daniel C. Andersson et al.   Cell Metabolism

Inherited Dysfunction of Sarcoplasmic Reticulum Ca 2+ Handling and Arrhythmogenesis

(2011) Silvia G. Priori et al.   CIRCULATION RESEARCH

Cyclization of the Intrinsically Disordered α1SDihydropyridine Receptor II-III Loop Enhances Secondary Structure andin VitroFunction

(2011) Han-Shen Tae et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apo and InsP3-bound crystal structures of the ligand-binding domain of an InsP3 receptor

(2011) Chun-Chi Lin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Type 1 ryanodine receptor knock-in mutation causing central core disease of skeletal muscle also displays a neuronal phenotype

(2011) V. De Crescenzo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structural biology of ryanodine receptors

(2011) Lynn Kimlicka et al.   Science China-Life Sciences

Flexible Architecture of IP3R1 by Cryo-EM

(2011) Steven J. Ludtke et al.   STRUCTURE

The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching

(2011) Paolo A. Lobo et al.   STRUCTURE

Mechanistic models for muscle diseases and disorders originating in the sarcoplasmic reticulum

(2010) David H. MacLennan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mapping the Ryanodine Receptor FK506-binding Protein Subunit Using Fluorescence Resonance Energy Transfer

(2010) Razvan L. Cornea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic, inter-subunit interactions between the N-terminal and central mutation regions of cardiac ryanodine receptor

(2010) Z. Liu et al.   JOURNAL OF CELL SCIENCE

The amino-terminal disease hotspot of ryanodine receptors forms a cytoplasmic vestibule

(2010) Ching-Chieh Tung et al.   NATURE

Multi-minicore disease and atypical periodic paralysis associated with novel mutations in the skeletal muscle ryanodine receptor (RYR1) gene

(2010) Haiyan Zhou et al.   NEUROMUSCULAR DISORDERS

Ryanodine receptor channelopathies

(2010) Matthew J. Betzenhauser et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Ryanodine Receptors: Structure, Expression, Molecular Details, and Function in Calcium Release

(2010) J. T. Lanner et al.   Cold Spring Harbor Perspectives in Biology

The Relationship Between Exertional Heat Illness, Exertional Rhabdomyolysis, and Malignant Hyperthermia

(2009) John F. Capacchione et al.   ANESTHESIA AND ANALGESIA

Exertional Rhabdomyolysis and Malignant Hyperthermia in a Patient with Ryanodine Receptor Type 1 Gene, L-type Calcium Channel α-1 Subunit Gene, and Calsequestrin-1 Gene Polymorphisms

(2009) John F. Capacchione et al.   ANESTHESIOLOGY

Ca2+ signaling in striated muscle: the elusive roles of triadin, junctin, and calsequestrin

(2009) Nicole A. Beard et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

FRET-based mapping of calmodulin bound to the RyR1 Ca2+ release channel

(2009) R. L. Cornea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of type I ryanodine receptor amino-terminal  -trefoil domain reveals a disease-associated mutation "hot spot" loop

(2009) F. J. Amador et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal Structures of the N-Terminal Domains of Cardiac and Skeletal Muscle Ryanodine Receptors: Insights into Disease Mutations

(2009) Paolo Antonio Lobo et al.   STRUCTURE

Coordinated Movement of Cytoplasmic and Transmembrane Domains of RyR1 upon Gating

(2009) Montserrat Samsó et al.   PLOS BIOLOGY

Reduced Threshold for Luminal Ca2+Activation of RyR1 Underlies a Causal Mechanism of Porcine Malignant Hyperthermia

(2008) Dawei Jiang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ryanodine Receptor Structure: Progress and Challenges

(2008) Susan L. Hamilton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S100A1 and Calmodulin Compete for the Same Binding Site on Ryanodine Receptor

(2008) Nathan T. Wright et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel

(2008) I. I. Serysheva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arrhythmogenic Right Ventricular Dysplasia

(2008) Palaniappan Muthappan et al.   PROGRESS IN CARDIOVASCULAR DISEASES