High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog)
出版年份 2020 全文链接
标题
High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog)
作者
关键词
-
出版物
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Volume 40, Issue 8, Pages 1854-1869
出版商
Ovid Technologies (Wolters Kluwer Health)
发表日期
2020-06-25
DOI
10.1161/atvbaha.120.314458
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Epigenetics, cardiovascular disease, and cellular reprogramming
- (2019) Keith Al-Hasani et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- PTEN interacts with the transcription machinery on chromatin and regulates RNA polymerase II-mediated transcription
- (2019) Nicole Steinbach et al. NUCLEIC ACIDS RESEARCH
- Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway
- (2019) Yu-Ru Lee et al. SCIENCE
- 5-Aza-2′-deoxycytidine, a DNA methylation inhibitor, attenuates hypoxic pulmonary hypertension via demethylation of the PTEN promoter
- (2019) Xi-Qian Xing et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Drug Design Targeting T-Cell Factor-Driven Epithelial–Mesenchymal Transition as a Therapeutic Strategy for Colorectal Cancer
- (2019) Adedoyin D. Abraham et al. JOURNAL OF MEDICINAL CHEMISTRY
- PTEN (Phosphatase and Tensin Homolog) Protects Against Ang II (Angiotensin II)-Induced Pathological Vascular Fibrosis and Remodeling—Brief Report
- (2019) Sizhao Lu et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Epigenomes in Cardiovascular Disease
- (2018) Manuel Rosa-Garrido et al. CIRCULATION RESEARCH
- Epigenetic modulation of vascular diseases: Assessing the evidence and exploring the opportunities
- (2018) Gabriele G. Schiattarella et al. VASCULAR PHARMACOLOGY
- Atherosclerosis-associated differentially methylated regions can reflect the disease phenotype and are often at enhancers
- (2018) Michelle Lacey et al. ATHEROSCLEROSIS
- DNA methylation processes in atheosclerotic plaque
- (2018) Einari Aavik et al. ATHEROSCLEROSIS
- Aberrant promoter methylation of multiple genes in VSMC proliferation induced by Hcy
- (2017) Sheng-Chao Ma et al. Molecular Medicine Reports
- Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis
- (2017) Michael J. Bollong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analysis of the expression level and methylation of tumor protein p53, phosphatase and tensin homolog and mutS homolog 2 in N-methyl-N-nitrosourea-induced thymic lymphoma in C57BL/6 mice
- (2017) Xueyun Huo et al. Oncology Letters
- The Yin–Yang Dynamics of DNA Methylation Is the Key Regulator for Smooth Muscle Cell Phenotype Switch and Vascular RemodelingHighlights
- (2016) Jianhui Zhuang et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Vascular Smooth Muscle Cells
- (2016) Mark W. Majesky ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Differentiated Smooth Muscle Cells Generate a Subpopulation of Resident Vascular Progenitor Cells in the Adventitia Regulated by Klf4Novelty and Significance
- (2016) Mark W. Majesky et al. CIRCULATION RESEARCH
- Hypo-CpG methylation controls PTEN expression and cell apoptosis in irradiated lung
- (2016) Xiuwu Zhang et al. FREE RADICAL RESEARCH
- Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation
- (2016) Henrick Horita et al. Nature Communications
- Epigenetic Control of Smooth Muscle Cell Identity and Lineage Memory
- (2015) Delphine Gomez et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- DNA Methylation Map of Human Atherosclerosis
- (2014) S. Zaina et al. Circulation-Cardiovascular Genetics
- Aberrant CpG island methylation of PTEN is an early event in nasopharyngeal carcinoma and a potential diagnostic biomarker
- (2014) JINBANG LI et al. ONCOLOGY REPORTS
- DNA demethylation in the PTEN gene promoter induced by 5-azacytidine activates PTEN expression in the MG-63 human osteosarcoma cell line
- (2014) DEYE SONG et al. Experimental and Therapeutic Medicine
- 5-Aza-2′-deoxycytidine inhibited PDGF-induced rat airway smooth muscle cell phenotypic switching
- (2013) Yunye Ning et al. ARCHIVES OF TOXICOLOGY
- Ten-Eleven Translocation-2 (TET2) Is a Master Regulator of Smooth Muscle Cell Plasticity
- (2013) Renjing Liu et al. CIRCULATION
- Concise Drug Review: Azacitidine and Decitabine
- (2013) E. J. B. Derissen et al. ONCOLOGIST
- Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling
- (2012) J. M. Spin et al. CARDIOVASCULAR RESEARCH
- Systemic Elevation of PTEN Induces a Tumor-Suppressive Metabolic State
- (2012) Isabel Garcia-Cao et al. CELL
- DNMT1-mediated PTEN hypermethylation confers hepatic stellate cell activation and liver fibrogenesis in rats
- (2012) Er-Bao Bian et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Epigenetic Control of Smooth Muscle Cell Differentiation and Phenotypic Switching in Vascular Development and Disease
- (2011) Matthew R. Alexander et al. Annual Review of Physiology
- SDF-1α Induction in Mature Smooth Muscle Cells by Inactivation of PTEN Is a Critical Mediator of Exacerbated Injury-Induced Neointima Formation
- (2011) Raphael A. Nemenoff et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Progress and challenges in translating the biology of atherosclerosis
- (2011) Peter Libby et al. NATURE
- Restenosis after PCI. Part 1: pathophysiology and risk factors
- (2011) J. Wouter Jukema et al. Nature Reviews Cardiology
- Inactivation of the tumour suppressor, PTEN, in smooth muscle promotes a pro-inflammatory phenotype and enhances neointima formation
- (2010) Seth B. Furgeson et al. CARDIOVASCULAR RESEARCH
- Targeted Deletion of PTEN in Smooth Muscle Cells Results in Vascular Remodeling and Recruitment of Progenitor Cells Through Induction of Stromal Cell–Derived Factor-1α
- (2008) Raphael A. Nemenoff et al. CIRCULATION RESEARCH
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