Anti-parasite drug ivermectin can suppress ovarian cancer by regulating lncRNA-EIF4A3-mRNA axes

MASS SPECTROMETRY‐BASED PERSONALIZED DRUG THERAPY

(2020) Jia‐Jia Cui et al.   MASS SPECTROMETRY REVIEWS

Vaginal dryness: individualised patient profiles, risks and mitigating measures

(2019) Vadym Goncharenko et al.   EPMA Journal

The MAPK Pathway-Based Drug Therapeutic Targets in Pituitary Adenomas

(2019) Miaolong Lu et al.   Frontiers in Endocrinology

Doxycycline, salinomycin, monensin and ivermectin repositioned as cancer drugs

(2019) Anna Markowska et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Notch2 pathway mediates breast cancer cellular dormancy and mobilisation in bone and contributes to haematopoietic stem cell mimicry

(2019) Mattia Capulli et al.   BRITISH JOURNAL OF CANCER

Beyond the unwinding: Role of TOP1MT in mitochondrial translation

(2019) Simone A Baechler et al.   CELL CYCLE

The Mitochondrion as an Emerging Therapeutic Target in Cancer

(2019) Katherine G. Roth et al.   TRENDS IN MOLECULAR MEDICINE

Identification of clinical trait–related lncRNA and mRNA biomarkers with weighted gene co-expression network analysis as useful tool for personalized medicine in ovarian cancer

(2019) Na Li et al.   EPMA Journal

Ivermectin inhibits canine mammary tumor growth by regulating cell cycle progression and WNT signaling

(2019) Hongxiu Diao et al.   BMC Veterinary Research

Ivermectin augments the in vitro and in vivo efficacy of cisplatin in epithelial ovarian cancer by suppressing Akt/mTOR signaling

(2019) Xiaohong Zhang et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

LINC00680 and TTN-AS1 Stabilized by EIF4A3 Promoted Malignant Biological Behaviors of Glioblastoma Cells

(2019) Wei Tang et al.   Molecular Therapy-Nucleic Acids

Antibiotic ivermectin selectively induces apoptosis in chronic myeloid leukemia through inducing mitochondrial dysfunction and oxidative stress

(2018) Jiaqiao Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sanguinarine inhibits epithelial ovarian cancer development via regulating long non-coding RNA CASC2-EIF4A3 axis and/or inhibiting NF-κB signaling or PI3K/AKT/mTOR pathway

(2018) Suxian Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

Upregulation of SNHG3 expression associated with poor prognosis and enhances malignant progression of ovarian cancer

(2018) Lan Hong et al.   Cancer Biomarkers

Quantitative analysis of the mitochondrial proteome in human ovarian carcinomas

(2018) Na Li et al.   ENDOCRINE-RELATED CANCER

The lncRNA SNHG3 regulates energy metabolism of ovarian cancer by an analysis of mitochondrial proteomes

(2018) Na Li et al.   GYNECOLOGIC ONCOLOGY

PUF60-activated exons uncover altered 3′ splice-site selection by germline missense mutations in a single RRM

(2018) Jana Královičová et al.   NUCLEIC ACIDS RESEARCH

Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers

(2018) Jose Muñoz et al.   PLoS Neglected Tropical Diseases

The crucial role of multiomic approach in cancer research and clinically relevant outcomes

(2018) Miaolong Lu et al.   EPMA Journal

Macrocyclic lactones inhibit nasopharyngeal carcinoma cells proliferation through PAK1 inhibition and reduce in vivo tumor growth

(2018) Franck Gallardo et al.   Drug Design Development and Therapy

Effects of Ivermectin Exposure on Regeneration of D. dorotocephala Planaria: Exploiting Human-Approved Ion Channel Drugs as Morphoceuticals

(2018) Nina N. Ferenc et al.   MACROMOLECULAR BIOSCIENCE

Transcriptome-wide analysis links the short-term expression of the b isoforms of TIA proteins to protective proteostasis-mediated cell quiescence response

(2018) Isabel Carrascoso et al.   PLoS One

β-TrCP upregulates HIF-1 in prostate cancer cells

(2018) Maya Cohen et al.   PROSTATE

Assessment of P-glycoprotein gene expression in adult stage of Haemonchus contortus in vivo exposed to ivermectin

(2018) L. Maté et al.   VETERINARY PARASITOLOGY

Ivermectin: enigmatic multifaceted ‘wonder’ drug continues to surprise and exceed expectations

(2017) Andy Crump   JOURNAL OF ANTIBIOTICS

Ivermectin as an inhibitor of cancer stem‑like cells

(2017) Guadalupe Dominguez‑Gomez et al.   Molecular Medicine Reports

Ivermectin – Old Drug, New Tricks?

(2017) Roz Laing et al.   TRENDS IN PARASITOLOGY

Postmenopausal breast cancer: European challenge and innovative concepts

(2017) Ivica Smokovski et al.   EPMA Journal

Breast cancer and Flammer syndrome: any symptoms in common for prediction, prevention and personalised medical approach?

(2017) Pavol Zubor et al.   EPMA Journal

“Pre-metastatic niches” in breast cancer: are they created by or prior to the tumour onset? “Flammer Syndrome” relevance to address the question

(2017) Rostyslav Bubnov et al.   EPMA Journal

Pattern recognition for predictive, preventive, and personalized medicine in cancer

(2017) Tingting Cheng et al.   EPMA Journal

Ivermectin induces PAK1-mediated cytostatic autophagy in breast cancer

(2016) Kui Wang et al.   Autophagy

Ivermectin Induces Cytostatic Autophagy by Blocking the PAK1/Akt Axis in Breast Cancer

(2016) Q. Dou et al.   CANCER RESEARCH

Synergism between ivermectin and the tyrosine kinase/ P -glycoprotein inhibitor crizotinib against Haemonchus contortus larvae in vitro

(2016) Ali Raza et al.   VETERINARY PARASITOLOGY

Long noncoding RNA H19 indicates a poor prognosis of colorectal cancer and promotes tumor growth by recruiting and binding to eIF4A3

(2016) Dong Han et al.   Oncotarget

Expression and Clinical Significance of the Novel Long Noncoding RNA ZNF674-AS1 in Human Hepatocellular Carcinoma

(2016) Lufei Zhang et al.   Biomed Research International

Exploration of Molecular Network Variations in Different Subtypes of Human Non-functional Pituitary Adenomas

(2016) Xianquan Zhan et al.   Frontiers in Endocrinology

Medicine in the early twenty-first century: paradigm and anticipation - EPMA position paper 2016

(2016) Olga Golubnitschaja et al.   EPMA Journal

DEAD-box RNA helicase DDX23 modulates glioma malignancy via elevating miR-21 biogenesis

(2015) Jinlong Yin et al.   BRAIN

Loperamide-induced expression of immune and inflammatory genes in Collies associated with ivermectin sensitivity

(2015) M. Zhu et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

EPMA position paper in cancer: current overview and future perspectives

(2015) Godfrey Grech et al.   EPMA Journal

HE4 expression is associated with hormonal elements and mediated by importin-dependent nuclear translocation

(2014) Elizabeth Lokich et al.   Scientific Reports

Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency

(2013) Valérie Serre et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease

(2013) Jeannie T. Lee et al.   CELL

Multi-parameter systematic strategies for predictive, preventive and personalised medicine in cancer

(2013) Rong Hu et al.   EPMA Journal

Mitochondria “fuel” breast cancer metabolism: Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells

(2012) Federica Sotgia et al.   CELL CYCLE

History of Avermectin and Ivermectin, with Notes on the History of Other Macrocyclic Lactone Antiparasitic Agents

(2012) William C. Campbell   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

General Report & Recommendations in Predictive, Preventive and Personalised Medicine 2012: White Paper of the European Association for Predictive, Preventive and Personalised Medicine

(2012) Olga Golubnitschaja et al.   EPMA Journal

The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells

(2010) S. Sharmeen et al.   BLOOD