Role of HSP60/HSP10 in Lung Cancer: Simple Biomarkers or Leading Actors?

Hsp60 as a Novel Target in IBD Management: A Prospect

(2019) Francesco Cappello et al.   Frontiers in Pharmacology

Fhit–Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells

(2019) Teresa Druck et al.   Cell Death & Disease

Differential expression of Annexin 2, SPINK1, and Hsp60 predict progression of prostate cancer through bifurcated WHO Gleason score categories in African American men

(2018) Desta A. Beyene et al.   PROSTATE

Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth

(2018) Chao Zhou et al.   Cell Death & Disease

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Potential involvement of heat shock proteins in pancreatic-duodenal homeobox-1-mediated effects on the genesis of gastric cancer: A 2D gel-based proteomic study

(2018) Juan Ma et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Mutant p53 as a guardian of the cancer cell

(2018) Fiamma Mantovani et al.   CELL DEATH AND DIFFERENTIATION

Bronchial inflammation and bacterial load in stable COPD is associated with TLR4 overexpression

(2017) Antonino Di Stefano et al.   EUROPEAN RESPIRATORY JOURNAL

HSP60 activity on human bronchial epithelial cells

(2017) Claudia Sangiorgi et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Unconventional Secretion of Heat Shock Proteins in Cancer

(2017) Tiago Góss Santos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.

(2017) Francesco Trapasso et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The dissociation of the Hsp60/pro-Caspase-3 complex by bis(pyridyl)oxadiazole copper complex ( CubipyOXA ) leads to cell death in NCI-H292 cancer cells

(2017) Celeste Caruso Bavisotto et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Heat Shock Proteins and Cancer

(2017) Jianming Wu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implications

(2017) Nieves González et al.   Oncotarget

Lung cancer survival only increases by a small amount despite recent treatment advances

(2017) Sanjeet Bagcchi   Lancet Respiratory Medicine

The Fhit protein: an opportunity to overcome chemoresistance

(2016) Eugenio Gaudio et al.   Aging-US

Heat Shock Protein (HSP) Drug Discovery and Development: Targeting Heat Shock Proteins in Disease

(2016) Liza Shrestha et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Heat Shock Proteins Promote Cancer: It's a Protection Racket

(2016) Stuart K. Calderwood et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hsp60 exerts a tumor suppressor function by inducing cell differentiation and inhibiting invasion in hepatocellular carcinoma

(2016) Jing Zhang et al.   Oncotarget

Heat shock protein 60 levels in tissue and circulating exosomes in human large bowel cancer before and after ablative surgery

(2015) Claudia Campanella et al.   CANCER

Characterization and function analysis of Hsp60 and Hsp10 under different acute stresses in black tiger shrimp, Penaeus monodon

(2015) Jinxuan Shi et al.   CELL STRESS & CHAPERONES

The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells

(2015) Claudia Campanella et al.   Oncotarget

Upon oxidative stress, the antiapoptotic Hsp60/procaspase-3 complex persists in mucoepidermoid carcinoma cells

(2015) C Campanella et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Histone deacetylase inhibitor treatment induces ‘BRCAness’ and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells

(2015) Kyungsoo Ha et al.   Oncotarget

Lysophosphatidic acid-induced IL-8 secretion involves MSK1 and MSK2 mediated activation of CREB1 in human fibroblast-like synoviocytes

(2014) Chenqi Zhao et al.   BIOCHEMICAL PHARMACOLOGY

Upregulation of heat shock proteins and the promotion of damage-associated molecular pattern signals in a colorectal cancer model by modulated electrohyperthermia

(2014) Gabor Andocs et al.   CELL STRESS & CHAPERONES

Senescence and apoptosis: dueling or complementary cell fates?

(2014) B. G. Childs et al.   EMBO REPORTS

Hsp10 nuclear localization and changes in lung cells response to cigarette smoke suggest novel roles for this chaperonin

(2014) S. Corrao et al.   Open Biology

ATP-driven molecular chaperone machines

(2013) Daniel K. Clare et al.   BIOPOLYMERS

Extracellular HSP60 induces inflammation through activating and up-regulating TLRs in cardiomyocytes

(2013) Jing Tian et al.   CARDIOVASCULAR RESEARCH

Hsp60, a Novel Target for Antitumor Therapy: Structure-Function Features and Prospective Drugs Design

(2013) Andrea Pace et al.   CURRENT PHARMACEUTICAL DESIGN

Hsp60 chaperonopathies and chaperonotherapy: targets and agents

(2013) Francesco Cappello et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Geldanamycin-Induced Osteosarcoma Cell Death Is Associated with Hyperacetylation and Loss of Mitochondrial Pool of Heat Shock Protein 60 (Hsp60)

(2013) Magdalena Gorska et al.   PLoS One

Crystal structure of a GroEL-ADP complex in the relaxed allosteric state at 2.7 A resolution

(2013) X. Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Tyrosine Nitration: Biochemical Mechanisms and Structural Basis of Functional Effects

(2012) Rafael Radi   ACCOUNTS OF CHEMICAL RESEARCH

HSP60 is transported through the secretory pathway of 3-MCA-induced fibrosarcoma tumour cells and undergoes N-glycosylation

(2012) Dana Hayoun et al.   FEBS Journal

Prognostic significance of heat shock proteins in urothelial carcinoma of the urinary bladder

(2012) Hui-Jung Yu et al.   HISTOPATHOLOGY

Anticancer Drugs Cause Release of Exosomes with Heat Shock Proteins from Human Hepatocellular Carcinoma Cells That Elicit Effective Natural Killer Cell Antitumor Responsesin Vitro

(2012) Li-Hong Lv et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Odyssey of Hsp60 from Tumor Cells to Other Destinations Includes Plasma Membrane-Associated Stages and Golgi and Exosomal Protein-Trafficking Modalities

(2012) Claudia Campanella et al.   PLoS One

Identification and verification of heat shock protein 60 as a potential serum marker for colorectal cancer

(2011) Céline Hamelin et al.   FEBS Journal

Heat shock protein-60 expression was significantly correlated with the prognosis of lung adenocarcinoma

(2011) Xin Xu et al.   JOURNAL OF SURGICAL ONCOLOGY

Convergent Sets of Data from In Vivo and In Vitro Methods Point to an Active Role of Hsp60 in Chronic Obstructive Pulmonary Disease Pathogenesis

(2011) Francesco Cappello et al.   PLoS One

Hsp60 expression, new locations, functions, and perspectives for cancer diagnosis and therapy

(2010) Francesco Cappello et al.   CANCER BIOLOGY & THERAPY

Stress Proteins and Cytokines are Urinary Biomarkers for Diagnosis and Staging of Bladder Cancer

(2010) David Margel et al.   EUROPEAN UROLOGY

Agglutination ofHistoplasma capsulatumby IgG Monoclonal Antibodies against Hsp60 Impacts Macrophage Effector Functions

(2010) Allan Jefferson Guimarães et al.   INFECTION AND IMMUNITY

Hsp60 Is Actively Secreted by Human Tumor Cells

(2010) Anna M. Merendino et al.   PLoS One

Cytosolic Hsp60 Is Involved in the NF-κB-Dependent Survival of Cancer Cells via IKK Regulation

(2010) Jung Nyeo Chun et al.   PLoS One

Immunohistochemical Expression of Hsp60 Correlates With Tumor Progression and Hormone Resistance in Prostate Cancer

(2010) Carolina Castilla et al.   UROLOGY

Fragile gene product, Fhit, in oxidative and replicative stress responses

(2009) Hiroshi Okumura et al.   CANCER SCIENCE

Interaction between HSP60 and β-catenin promotes metastasis

(2009) Ya-Ping Tsai et al.   CARCINOGENESIS

Features of senescence and cell death induced by doxorubicin in A549 cells: organization and level of selected cytoskeletal proteins

(2009) Anna Litwiniec et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Heat Shock Protein 60, via MyD88 Innate Signaling, Protects B Cells from Apoptosis, Spontaneous and Induced

(2009) M. Cohen-Sfady et al.   JOURNAL OF IMMUNOLOGY

Heat shock protein 60 (HSP60) stimulates neutrophil effector functions

(2009) Anke Osterloh et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human Hsp10 and Early Pregnancy Factor (EPF) and their relationship and involvement in cancer and immunity: Current knowledge and perspectives

(2009) Simona Corrao et al.   LIFE SCIENCES

Expression of Heat Shock Protein 60 kDa Is Upregulated in Cervical Cancer

(2009) You Jin Hwang et al.   YONSEI MEDICAL JOURNAL

Heat shock proteins 27, 60 and 70 as prognostic markers of prostate cancer 

(2008) AXEL GLAESSGEN et al.   APMIS

Fhit tumor suppressor: guardian of the preneoplastic genome

(2008) Flavia Pichiorri et al.   Future Oncology

Cigarette smoke increases Toll-like receptor 4 and modifies lipopolysaccharide-mediated responses in airway epithelial cells

(2008) Elisabetta Pace et al.   IMMUNOLOGY

Immunohistochemical analysis of possible chemoresistance markers identified by micro-arrays on serous ovarian carcinomas

(2008) Bernard Têtu et al.   MODERN PATHOLOGY

Requirement for binding multiple ATPs to convert a GroEL ring to the folding-active state

(2008) E. Chapman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA