Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation
出版年份 2020 全文链接
标题
Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation
作者
关键词
-
出版物
Cancers
Volume 12, Issue 3, Pages 723
出版商
MDPI AG
发表日期
2020-03-19
DOI
10.3390/cancers12030723
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Alternative splicing of Ikaros regulates the FUT4/LeX-α5β1 integrin-FAK axis in acute lymphoblastic leukemia
- (2019) Lijun Yi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The prognostic significance of global aberrant alternative splicing in patients with myelodysplastic syndrome
- (2018) Yi-Tsung Yang et al. Blood Cancer Journal
- Aberrant splicing in B-cell acute lymphoblastic leukemia
- (2018) Kathryn L Black et al. NUCLEIC ACIDS RESEARCH
- Splicing modulation as novel therapeutic strategy against diffuse malignant peritoneal mesothelioma
- (2018) Rocco Sciarrillo et al. EBioMedicine
- JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias
- (2017) C Delgado-Martin et al. LEUKEMIA
- Alternative splicing discriminates molecular subtypes and has prognostic impact in diffuse large B-cell lymphoma
- (2017) S-K Leivonen et al. Blood Cancer Journal
- Shift in energy metabolism caused by glucocorticoids enhances the effect of cytotoxic anti-cancer drugs against acute lymphoblastic leukemia cells
- (2017) Shigeki Aoki et al. Oncotarget
- Complex heatmaps reveal patterns and correlations in multidimensional genomic data
- (2016) Zuguang Gu et al. BIOINFORMATICS
- The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia
- (2016) A. Wojtuszkiewicz et al. HAEMATOLOGICA
- Clinical significance of the ABCB1 and ABCG2 gene expression levels in acute lymphoblastic leukemia
- (2016) I. Olarte Carrillo et al. Hematology
- Successful Therapy Reduction and Intensification for Childhood Acute Lymphoblastic Leukemia Based on Minimal Residual Disease Monitoring: Study ALL10 From the Dutch Childhood Oncology Group
- (2016) Rob Pieters et al. JOURNAL OF CLINICAL ONCOLOGY
- Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins
- (2016) Stanley Chun-Wei Lee et al. NATURE MEDICINE
- g:Profiler—a web server for functional interpretation of gene lists (2016 update)
- (2016) Jüri Reimand et al. NUCLEIC ACIDS RESEARCH
- Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia
- (2016) Hsin-An Hou et al. Oncotarget
- The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia
- (2016) A. Wojtuszkiewicz et al. HAEMATOLOGICA
- Using RNA-sequencing to Detect Novel Splice Variants Related to Drug Resistance in In Vitro Cancer Models
- (2016) Rocco Sciarrillo et al. Jove-Journal of Visualized Experiments
- MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia
- (2015) C. L. Jones et al. BLOOD
- Folylpolyglutamate synthetase splicing alterations in acute lymphoblastic leukemia are provoked by methotrexate and other chemotherapeutics and mediate chemoresistance
- (2015) Anna Wojtuszkiewicz et al. INTERNATIONAL JOURNAL OF CANCER
- Childhood Acute Lymphoblastic Leukemia: Progress Through Collaboration
- (2015) Ching-Hon Pui et al. JOURNAL OF CLINICAL ONCOLOGY
- Tumor suppressor IKZF1 mediates glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia
- (2015) R Marke et al. LEUKEMIA
- The spliceosome is a therapeutic vulnerability in MYC-driven cancer
- (2015) Tiffany Y.-T. Hsu et al. NATURE
- MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
- (2015) Cheryl M. Koh et al. NATURE
- Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response
- (2014) V Marcel et al. CELL DEATH AND DIFFERENTIATION
- Pre-mRNA splicing in cancer: the relevance in oncogenesis, treatment and drug resistance
- (2014) Anna Wojtuszkiewicz et al. Expert Opinion on Drug Metabolism & Toxicology
- Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A
- (2013) C. G. Hubert et al. GENES & DEVELOPMENT
- Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors
- (2013) D. Niewerth et al. HAEMATOLOGICA
- Mutational analysis of splicing machinery genesSF3B1, U2AF1andSRSF2in myelodysplasia and other common tumors
- (2013) Eun Mi Je et al. INTERNATIONAL JOURNAL OF CANCER
- Relapsed childhood acute lymphoblastic leukaemia
- (2013) Deepa Bhojwani et al. LANCET ONCOLOGY
- Software for Computing and Annotating Genomic Ranges
- (2013) Michael Lawrence et al. PLoS Computational Biology
- The spliceosome as a target of novel antitumour drugs
- (2012) Sophie Bonnal et al. NATURE REVIEWS DRUG DISCOVERY
- Chronic Lymphocytic Leukemia withSF3B1Mutation
- (2012) Victor Quesada et al. NEW ENGLAND JOURNAL OF MEDICINE
- Alternative splicing networks regulated by signaling in human T cells
- (2012) N. M. Martinez et al. RNA
- Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies
- (2011) L. E. Hogan et al. BLOOD
- Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
- (2011) D. Rossi et al. BLOOD
- Regulation of alternative splicing by the core spliceosomal machinery
- (2011) A. L. Saltzman et al. GENES & DEVELOPMENT
- Transcriptomes of the B and T Lineages Compared by Multiplatform Microarray Profiling
- (2011) M. W. Painter et al. JOURNAL OF IMMUNOLOGY
- Frequent pathway mutations of splicing machinery in myelodysplasia
- (2011) Kenichi Yoshida et al. NATURE
- SomaticSF3B1Mutation in Myelodysplasia with Ring Sideroblasts
- (2011) E. Papaemmanuil et al. NEW ENGLAND JOURNAL OF MEDICINE
- Long-Term Outcome in Children With Relapsed Acute Lymphoblastic Leukemia After Time-Point and Site-of-Relapse Stratification and Intensified Short-Course Multidrug Chemotherapy: Results of Trial ALL-REZ BFM 90
- (2010) Gesche Tallen et al. JOURNAL OF CLINICAL ONCOLOGY
- IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL
- (2010) R P Kuiper et al. LEUKEMIA
- Protein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations
- (2010) Shlomit Kfir-Erenfeld et al. LEUKEMIA & LYMPHOMA
- The STRING database in 2011: functional interaction networks of proteins, globally integrated and scored
- (2010) D. Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
- (2009) Gabriela Bindea et al. BIOINFORMATICS
- rtracklayer: an R package for interfacing with genome browsers
- (2009) M. Lawrence et al. BIOINFORMATICS
- Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia
- (2009) R. W. Stam et al. BLOOD
- Long-term results of Dutch Childhood Oncology Group studies for children with acute lymphoblastic leukemia from 1984 to 2004
- (2009) W A Kamps et al. LEUKEMIA
- Cooperative study group for childhood acute lymphoblastic leukaemia (COALL): long-term results of trials 82,85,89,92 and 97
- (2009) G Escherich et al. LEUKEMIA
- Meayamycin inhibits pre-messenger RNA splicing and exhibits picomolar activity against multidrug-resistant cells
- (2009) B. J. Albert et al. MOLECULAR CANCER THERAPEUTICS
- Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches
- (2009) Mo Chen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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