Article
Engineering, Industrial
Lucia Corsini, Clara Beatriz Aranda-Jan, James Moultrie
Summary: This study reviews twelve case studies of 3D printed products to examine the effects of 3D printing on the humanitarian supply chain. The findings reveal that 3D printing is impacting the supply chain in terms of networks, governance, processes, and products. The study suggests the need for a holistic supply chain approach that includes local production and design.
PRODUCTION PLANNING & CONTROL
(2022)
Article
Materials Science, Multidisciplinary
Amit Bandyopadhyay, Susmita Bose, Roger Narayan
Summary: This article reviews the impact of technological development on the manufacturing of biomedical devices and discusses the progress and regulatory issues of 3D printing biomaterials and medical devices.
Article
Construction & Building Technology
Ramani Ayyagari, Qian Chen, Borja Garcia de Soto
Summary: This paper investigates the consequences of incorporating 3D printing in a traditional construction supply chain and demonstrates its potential in reducing complexity. The study uses a two-story office building project in the UAE as a case study and compares the traditional construction supply chain with the construction supply chain utilizing 3D printing. Simulation results show that the 3D printed construction supply chain requires 21% more effort and experiences a 6% reduction in production rate compared to the traditional supply chain. The findings should be considered as part of construction innovation and future research will focus on projects with complex geometries.
AUTOMATION IN CONSTRUCTION
(2023)
Review
Chemistry, Multidisciplinary
Yue Wang, Haitao Cui, Timothy Esworthy, Deqing Mei, Yancheng Wang, Lijie Grace Zhang
Summary: The rapid development of 3D printing has had a significant impact on the field of biomedical engineering, particularly 4D printing. While there has been progress made in the development of 4D printing for tissue scaffolds and medical devices, there are limitations in printable smart materials and achievable responses with current stimulation sources. This review highlights recent progress in 4D printing, focusing on printing mechanisms, smart ink mechanisms, structural design, and printing technologies. It also summarizes recent studies on tissue/organ regeneration and medical device applications, and discusses current challenges and future perspectives of 4D printing.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Milena Djukanovic, Ardijan Mavric, Jovana Jovanovic, Milovan Roganovic, Velibor Boskovic
Summary: Montenegro responded to the COVID-19 pandemic by utilizing 3D printers to produce medical equipment and designing innovative thermo-sensored medical gear to protect medical staff and patients, proving to be efficient and easy to use.
APPLIED SCIENCES-BASEL
(2021)
Article
Engineering, Industrial
Aamer Nazir, Aashir Azhar, Usman Nazir, Yun-Feng Liu, Waqar S. Qureshi, Jia-En Chen, Eisa Alanazi
Summary: This article discusses the importance of utilizing 3D printing technology to address supply chain disruptions during pandemics, especially for medical and protective equipment. The article emphasizes the potential of 3D printing in emergency situations and calls for more systematic research to fully exploit its potential in the pandemic and post-pandemic era.
JOURNAL OF MANUFACTURING SYSTEMS
(2021)
Review
Pharmacology & Pharmacy
Jiawei Wang, Yu Zhang, Niloofar Heshmati Aghda, Amit Raviraj Pillai, Rishi Thakkar, Ali Nokhodchi, Mohammed Maniruzzaman
Summary: With the advancement of additive manufacturing technology, 3D printed drug delivery medical devices have gained popularity for their customizable design, intricate structure, and personalized medication. Challenges remain in regulatory issues, scalability, and cost-effectiveness despite remarkable progress made by AM techniques.
ADVANCED DRUG DELIVERY REVIEWS
(2021)
Article
Materials Science, Multidisciplinary
Amit Bandyopadhyay, Sourabh Ghosh, Aldo R. Boccaccini, Susmita BosenAff
Summary: 3D printing, also known as additive manufacturing, has become a transformative technology platform impacting various disciplines. This special issue presents perspectives from scientists, engineers, and medical professionals on 3D printing of biomaterials and biomedical devices and covers a wide range of research topics involving different materials and printing processes.
JOURNAL OF MATERIALS RESEARCH
(2021)
Review
Engineering, Manufacturing
Gustavo Gonzalez, Ignazio Roppolo, Candido Fabrizio Pirri, Annalisa Chiappone
Summary: In the past two decades, 3D printing technology has emerged as an alternative for producing microfluidic devices, making their production cheaper, faster, and easier. However, there are still barriers to overcome in terms of technology and materials. This review evaluates the current state of polymeric 3D printing techniques and materials for manufacturing microfluidic chips, highlighting the latest innovations, materials, and applications.
ADDITIVE MANUFACTURING
(2022)
Review
Materials Science, Multidisciplinary
Henry A. Colorado, David E. Mendoza, Hua-Tay Lin, Elkin Gutierrez-Velasquez
Summary: This investigation analyzes the main contributions of additive manufacturing (AM) technology in fighting against the COVID-19 pandemic, specifically focusing on materials and applications. The study finds that 3D printing technology has played a significant role in producing protective masks, mechanical ventilator parts, social distancing signage, and parts for detection and disinfection equipment. These contributions are expected to continue increasing until a viable solution is found. Additionally, the study highlights the potential of collaborative efforts, technology networking, and adaptability among countries to address future challenges faced by human society.
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T
(2022)
Article
Biochemistry & Molecular Biology
Patrick M. Pysz, Julia K. Hoskins, Min Zou, Julie A. Stenken
Summary: This Perspective article discusses the potential of 3D printing technology in improving neuroscience measurement devices. It explores the use of 3D printing for device creation and the printing of peripheral objects required for functional devices. The most suitable 3D printing setup for microsampling devices with specific feature sizes is likely to involve 2-photon polymerization-based printers.
ACS CHEMICAL NEUROSCIENCE
(2023)
Review
Engineering, Industrial
Maximilian Kunovjanek, Christian Wankmueller
Summary: The study reveals that additive manufacturing was primarily used in the medical domain for producing standard medical items and also for new applications. Despite certain paradigm shifts and advancements, various obstacles still hinder lasting AM success.
JOURNAL OF MANUFACTURING TECHNOLOGY MANAGEMENT
(2021)
Article
Engineering, Industrial
Daniel Ramon-Lumbierres, F. Javier Heredia Cervera, Joaquim Minguella-Canela, Asier Muguruza-Blanco
Summary: This study introduces a new two-stage stochastic programming decision model for evaluating the introduction of new manufacturing technology into a supply chain, considering uncertainty in demand and determining the optimal customer order decoupling point. Through a generic supply chain graph, a mixed integer two-stage stochastic program is developed to find the optimal manufacturing technology and production quantity.
INTERNATIONAL JOURNAL OF PRODUCTION RESEARCH
(2021)
Article
Engineering, Industrial
Mohammad E. Arbabian
Summary: This study examines the impact of 3D printing on supply chains, including factors such as adoption by manufacturers and retailers, economic conditions, and government subsidies. It is found that retailer adoption of 3D printing can eliminate the double marginalization effect, serving as a new mechanism for coordinating the supply chain.
INTERNATIONAL JOURNAL OF PRODUCTION ECONOMICS
(2022)
Review
Chemistry, Physical
Y. C. Niranjan, S. G. Channabasavanna, Shankar Krishnapillai, R. Velmurugan, A. Rajesh Kannan, Dhanesh G. Mohan, Sasan Sattarpanah Karganroudi
Summary: The COVID-19 outbreak has disrupted global production rates and supply chains, but 3D printing has emerged as a potential solution to alleviate the crisis. 3D printing has been used to remotely produce personal protective equipment and has gained prominence in medical and non-medical applications.
Article
Pharmacology & Pharmacy
Camila J. Picco, Emilia Utomo, Andrea McClean, Juan Dominguez-Robles, Qonita Kurnia Anjani, Fabiana Volpe-Zanutto, Peter E. McKenna, Jonathan G. Acheson, Dessislava Malinova, Ryan F. Donnelly, Eneko Larraneta
Summary: Implantable drug-eluting devices have the potential to improve treatment of chronic conditions by providing sustained therapeutic effects and reducing pill burden for patients. The use of modern technologies like 3D printing allows for the production of customizable devices. In this study, subcutaneous implants loaded with olanzapine were formulated using the robocasting technique and demonstrated sustained drug release over a period of 200 days.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Correction
Pharmacology & Pharmacy
Emilia Utomo, Juan Dominguez-Robles, Natalia Moreno-Castellanos, Sarah A. Stewart, Camila J. Picco, Qonita Kurnia Anjani, Jon Ander Simon, Ivan Penuelas, Ryan F. Donnelly, Eneko Larraneta
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Pharmacology & Pharmacy
Nicole Ioannou, Jinyuan Luo, Mengqi Qin, Matteo Di Luca, Essyrose Mathew, Aristides D. Tagalakis, Dimitrios A. Lamprou, Cynthia Yu-Wai-Man
Summary: A sustained release 5-FU implant composed of PCL and CS was fabricated using 3D printing technology for preventing conjunctival fibrosis after glaucoma surgery. The implant released 5-FU steadily over 8 weeks and effectively suppressed fibroblast contractility. It exhibited biocompatibility, smooth surface, and degradability.
JOURNAL OF PHARMACY AND PHARMACOLOGY
(2023)
Article
Pharmacology & Pharmacy
Edward Weaver, Essyrose Mathew, Jay Caldwell, Andrew Hooker, Shahid Uddin, Dimitrios A. Lamprou
Summary: In this study, a UV LCD printer was used to produce microfluidic chips for liposomal synthesis, and the limitations of UV LCD printing in terms of resolution and print speed optimization were tested. By varying channel parameters, the essential properties for optimal liposomal formulation were investigated, and liposomes with sizes of approximately 120 nm and polydispersity index values of <= 0.12 were successfully synthesized. The influence of total flow rates and lipid choice on microfluidic setup optimization was also investigated in depth.
JOURNAL OF PHARMACY AND PHARMACOLOGY
(2023)
Review
Chemistry, Medicinal
Federica Sommonte, Nunzio Denora, Dimitrios A. Lamprou
Summary: Nanomedicine has developed rapidly in recent years for finding new therapies to treat challenging diseases. Microfluidic technology (MF) and additive manufacturing (AM) have gained popularity in the life science field, offering various benefits and drawbacks. By optimizing operational parameters, MF and AM can overcome existing limitations and their combination can provide highly-customizable and cost-effective solutions. This collaboration between MF and AM shows promising potential for impactful innovation in the near future.
Review
Pharmacology & Pharmacy
Masoud Adhami, Niamh K. Martin, Ciara Maguire, Aaron J. Courtenay, Ryan F. Donnelly, Juan Dominguez-Robles, Eneko Larraneta
Summary: Cardiovascular diseases are the leading cause of death globally. Drug eluting implants, that provide accurate drug release and minimize adverse side effects, have the potential for significant advancements in the treatment of these diseases.
EXPERT OPINION ON DRUG DELIVERY
(2023)
Article
Chemistry, Multidisciplinary
Li Zhao, Lalitkumar K. Vora, Stephen A. Kelly, Linlin Li, Eneko Larraneta, Helen O. McCarthy, Ryan F. Donnelly
Summary: Antibiotic resistance is a serious health problem and is expected to worsen in the future. Researchers have developed a hydrogel-forming microarray patch system that can deliver antibiotics in a sustained manner.
JOURNAL OF CONTROLLED RELEASE
(2023)
Editorial Material
Instruments & Instrumentation
Dimitrios Lamprou, Katie B. Ryan
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Article
Instruments & Instrumentation
Giulia Pitzanti, Valentyn Mohylyuk, Francesca Corduas, Niall M. Byrne, Jonathan A. Coulter, Dimitrios A. Lamprou
Summary: This study successfully formulated photocurable resins suitable for tissue engineering and other biomedical applications by testing and evaluating different polymer resins.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Article
Instruments & Instrumentation
Edward Weaver, Federica Sommonte, Andrew Hooker, Nunzio Denora, Shahid Uddin, Dimitrios A. Lamprou
Summary: A novel in-house method of microfluidic production of biologic-encapsulated SLNs is proposed, which allows for high encapsulation efficiencies of both large hydrophilic and small hydrophobic active pharmaceutical ingredients. The study provides useful insight into sustained kinetics through in vitro analysis, which is valuable for future in vivo studies.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
Article
Food Science & Technology
Jessica Ghodke, Sotirios I. Ekonomou, Edward Weaver, Dimitrios Lamprou, Olena Doran, Alexandros Ch. Stratakos
Summary: Liposomes enclosing eugenol were prepared using microfluidics in this study. Different lipids and microfluidic chip designs were used for the liposomal formulation. The encapsulation efficiency, stability, and eugenol release rate of the liposomes were evaluated. The results showed that the liposomal formulations can be used as delivery vehicles to enhance food safety.
Article
Green & Sustainable Science & Technology
Juan Dominguez-Robles, Elias Cuartas-Gomez, Sean Dynes, Emilia Utomo, Qonita Kurnia Anjani, Usanee Detamornrat, Ryan F. Donnelly, Natalia Moreno-Castellanos, Eneko Larraneta
Summary: Curcumin and lignin were combined with poly(caprolactone) to create 3D-printed wound dressings with antioxidant and antimicrobial properties. The dressings showed sustained release of DPA and CUR and demonstrated significant improvements in wound healing in animal studies. Histological examination also showed positive outcomes in terms of epithelization, inflammatory reaction, fibroblast proliferation, and neoangiogenesis.
SUSTAINABLE MATERIALS AND TECHNOLOGIES
(2023)
Article
Pharmacology & Pharmacy
Emilia Utomo, Juan Dominguez-Robles, Qonita Kurnia Anjani, Camila J. Picco, Anna Korelidou, Erin Magee, Ryan F. Donnelly, Eneko Larraneta
Summary: Bacterial vaginosis (BV) is an abnormal condition caused by changes in the vaginal microbiota. Current treatment involves the use of antibiotics, but frequent application is needed. This research proposes a prolonged release of metronidazole (MTZ) using biodegradable and biocompatible polymers in the form of intravaginal devices, which can reduce the frequency of administration.
INTERNATIONAL JOURNAL OF PHARMACEUTICS-X
(2023)
Article
Instruments & Instrumentation
Masoud Adhami, Camila J. Picco, Usanee Detamornrat, Qonita K. Anjani, Victoria A. Cornelius, Pamela Robles-Martinez, Andriana Margariti, Ryan F. Donnelly, Juan Dominguez-Robles, Eneko Larraneta
Summary: Cardiovascular diseases are a leading cause of death worldwide and significantly impact quality of life. 3D-printed biodegradable vascular grafts loaded with a drug called clopidogrel were developed using digital light processing technology. These grafts provide sustained drug release, reduce platelet deposition, and create a supportive environment for cellular attachment, viability, and growth.
DRUG DELIVERY AND TRANSLATIONAL RESEARCH
(2023)
