Host-Directed Therapies and Anti-Virulence Compounds to Address Anti-Microbial Resistant Tuberculosis Infection
出版年份 2020 全文链接
标题
Host-Directed Therapies and Anti-Virulence Compounds to Address Anti-Microbial Resistant Tuberculosis Infection
作者
关键词
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出版物
Applied Sciences-Basel
Volume 10, Issue 8, Pages 2688
出版商
MDPI AG
发表日期
2020-04-14
DOI
10.3390/app10082688
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition
- (2019) Jessica Gräb et al. Nature Communications
- Metformin as a host-directed therapeutic in tuberculosis: Is there a promise?
- (2019) Wing Wai Yew et al. TUBERCULOSIS
- A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis
- (2019) Eduardo P. Amaral et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Sirolimus and mTOR Inhibitors: A Review of Side Effects and Specific Management in Solid Organ Transplantation
- (2019) Lee S. Nguyen et al. DRUG SAFETY
- Investigating the Role of Everolimus in mTOR Inhibition and Autophagy Promotion as a Potential Host-Directed Therapeutic Target in Mycobacterium tuberculosis Infection
- (2019) Stephen Cerni et al. Journal of Clinical Medicine
- Matrix metalloproteinases: Expression, regulation and role in the immunopathology of tuberculosis
- (2019) Naveed Sabir et al. CELL PROLIFERATION
- Efferocytosis of Apoptotic Neutrophils Enhances Control of Mycobacterium tuberculosis in HIV-Coinfected Macrophages in a Myeloperoxidase-Dependent Manner
- (2019) Anna-Maria Andersson et al. Journal of Innate Immunity
- Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs
- (2019) Paulina Fernandez-Soto et al. Scientific Reports
- Regimens to treat multidrug-resistant tuberculosis: past, present and future perspectives
- (2019) Emanuele Pontali et al. European Respiratory Review
- Infect and Inject: How Mycobacterium tuberculosis Exploits Its Major Virulence-Associated Type VII Secretion System, ESX-1
- (2019) Sangeeta Tiwari et al. Microbiology Spectrum
- ESX/Type VII Secretion Systems—An Important Way Out for Mycobacterial Proteins
- (2019) Farzam Vaziri et al. Microbiology Spectrum
- Inhibiting Mycobacterium tuberculosis DosRST signaling by targeting response regulator DNA binding and sensor kinase heme
- (2019) Huiqing Zheng et al. ACS Chemical Biology
- Vitamin D status and risk of incident tuberculosis disease: A nested case-control study, systematic review, and individual-participant data meta-analysis
- (2019) Omowunmi Aibana et al. PLOS MEDICINE
- Type 2 Diabetes Mellitus and Altered Immune System Leading to Susceptibility to Pathogens, Especially Mycobacterium tuberculosis
- (2019) Steve Ferlita et al. Journal of Clinical Medicine
- Development of Potent Inhibitors of the Mycobacterium tuberculosis Virulence Factor Zmp1 and Evaluation of Their Effect on Mycobacterial Survival inside Macrophages
- (2018) Marco Paolino et al. ChemMedChem
- The Risk of TB in Patients With Type 2 Diabetes Initiating Metformin vs Sulfonylurea Treatment
- (2018) Sheng-Wei Pan et al. CHEST
- Type I interferons in tuberculosis: Foe and occasionally friend
- (2018) Lúcia Moreira-Teixeira et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Metformin is associated with a lower risk of active tuberculosis in patients with type 2 diabetes
- (2018) Shang-Yi Lin et al. RESPIROLOGY
- Higher serum 25-hydroxyvitamin D concentrations are associated with active pulmonary tuberculosis in hospitalised HIV infected patients in a low income tropical setting: a cross sectional study
- (2018) Cuthbert Musarurwa et al. BMC Pulmonary Medicine
- Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis
- (2018) Yitian Xu et al. PLoS Pathogens
- Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo
- (2018) Clare F. Vickers et al. JOURNAL OF MEDICINAL CHEMISTRY
- The tuberculosis-associated immune reconstitution inflammatory syndrome
- (2018) Naomi F. Walker et al. Current Opinion in HIV and AIDS
- Recent progress in understanding immune activation in the pathogenesis in HIV–tuberculosis co-infection
- (2018) Elsa du Bruyn et al. Current Opinion in HIV and AIDS
- Reactive Oxygen Species Localization Programs Inflammation to Clear Microbes of Different Size
- (2017) Annika Warnatsch et al. IMMUNITY
- Nitric Oxide Modulates Macrophage Responses toMycobacterium tuberculosisInfection through Activation of HIF-1α and Repression of NF-κB
- (2017) Jonathan Braverman et al. JOURNAL OF IMMUNOLOGY
- Efficacy of vitamin D3 supplementation in reducing incidence of pulmonary tuberculosis and mortality among HIV-infected Tanzanian adults initiating antiretroviral therapy: study protocol for a randomized controlled trial
- (2017) Christopher R. Sudfeld et al. Trials
- Non-Steroidal Anti-inflammatory Drugs As Host-Directed Therapy for Tuberculosis: A Systematic Review
- (2017) Vera M. Kroesen et al. Frontiers in Immunology
- A High-Throughput Assay for Developing Inhibitors of PhoP, a Virulence Factor of Mycobacterium tuberculosis
- (2016) Liqin Wang et al. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
- EspR-dependent ESAT-6 Protein Secretion ofMycobacterium tuberculosisRequires the Presence of Virulence Regulator PhoP
- (2016) Vijjamarri Anil Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Efferocytosis and extrusion of leukocytes determine the progression of early mycobacterial pathogenesis
- (2016) Rohola Hosseini et al. JOURNAL OF CELL SCIENCE
- Aberrant Inflammasome Activation Characterizes Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome
- (2016) Hong Yien Tan et al. JOURNAL OF IMMUNOLOGY
- CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease
- (2016) Shunsuke Sakai et al. PLoS Pathogens
- Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis
- (2016) Selvakumar Subbian et al. Frontiers in Immunology
- The DosR Regulon Modulates Adaptive Immunity and Is Essential forMycobacterium tuberculosisPersistence
- (2015) Smriti Mehra et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- The Carbonic Anhydrase Inhibitor Ethoxzolamide Inhibits the Mycobacterium tuberculosis PhoPR Regulon and Esx-1 Secretion and Attenuates Virulence
- (2015) Benjamin K. Johnson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Phenylbutyrate induces LL-37-dependent autophagy and intracellular killing ofMycobacterium tuberculosisin human macrophages
- (2015) Rokeya Sultana Rekha et al. Autophagy
- Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1
- (2015) Ruth Wassermann et al. Cell Host & Microbe
- Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis
- (2015) Bruno B. Andrade et al. JOURNAL OF IMMUNOLOGY
- 8-Hydroxyquinoline: a privileged structure with a broad-ranging pharmacological potential
- (2015) Yu'ning Song et al. MedChemComm
- HIV–tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling
- (2015) Rachel P. J. Lai et al. Nature Communications
- Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial
- (2015) Akhirunnesa Mily et al. PLoS One
- Statins Increase Rifampin Mycobactericidal Effect
- (2014) Lívia Silva Lobato et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Verapamil Increases the Bactericidal Activity of Bedaquiline against Mycobacterium tuberculosis in a Mouse Model
- (2014) Shashank Gupta et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- IFNG-mediated immune responses enhance autophagy againstMycobacterium tuberculosisantigens in patients with active tuberculosis
- (2014) Ana I Rovetta et al. Autophagy
- Anticytolytic Screen Identifies Inhibitors of Mycobacterial Virulence Protein Secretion
- (2014) Jan Rybniker et al. Cell Host & Microbe
- All-Trans Retinoic Acid-Triggered Antimicrobial Activity against Mycobacterium tuberculosis Is Dependent on NPC2
- (2014) M. Wheelwright et al. JOURNAL OF IMMUNOLOGY
- Vitamin D3 and phenylbutyrate promote development of a human dendritic cell subset displaying enhanced antimicrobial properties
- (2014) Anne M. van der Does et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Metformin as adjunct antituberculosis therapy
- (2014) A. Singhal et al. Science Translational Medicine
- Acceleration of Tuberculosis Treatment by Adjunctive Therapy with Verapamil as an Efflux Inhibitor
- (2013) Shashank Gupta et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Zafirlukast Inhibits Complexation of Lsr2 with DNA and Growth of Mycobacterium tuberculosis
- (2013) Lucile Pinault et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Efflux Inhibition with Verapamil Potentiates Bedaquiline in Mycobacterium tuberculosis
- (2013) Shashank Gupta et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Structure-Function Analysis of STING Activation by c[G(2′,5′)pA(3′,5′)p] and Targeting by Antiviral DMXAA
- (2013) Pu Gao et al. CELL
- Defensins: Natural component of human innate immunity
- (2013) Justyna Jarczak et al. HUMAN IMMUNOLOGY
- Little Peptide, Big Effects: The Role of LL-37 in Inflammation and Autoimmune Disease
- (2013) J. M. Kahlenberg et al. JOURNAL OF IMMUNOLOGY
- Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation
- (2013) Suraj P. Parihar et al. JOURNAL OF INFECTIOUS DISEASES
- Corticosteroids for prevention of mortality in people with tuberculosis: a systematic review and meta-analysis
- (2013) Julia A Critchley et al. LANCET INFECTIOUS DISEASES
- Identification of a candidate therapeutic autophagy-inducing peptide
- (2013) Sanae Shoji-Kawata et al. NATURE
- An Enzyme That Inactivates the Inflammatory Mediator Leukotriene B4 Restricts Mycobacterial Infection
- (2013) David M. Tobin et al. PLoS One
- Doxycycline and HIV Infection Suppress Tuberculosis-induced Matrix Metalloproteinases
- (2012) Naomi F. Walker et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- ESX-1 dependent impairment of autophagic flux byMycobacterium tuberculosisin human dendritic cells
- (2012) Alessandra Romagnoli et al. Autophagy
- Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections
- (2012) David M. Tobin et al. CELL
- Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway
- (2012) Robert O. Watson et al. CELL
- Efferocytosis Is an Innate Antibacterial Mechanism
- (2012) Constance J. Martin et al. Cell Host & Microbe
- Abelson Tyrosine Kinase Controls Phagosomal Acidification Required for Killing of Mycobacterium tuberculosis in Human Macrophages
- (2012) H. Bruns et al. JOURNAL OF IMMUNOLOGY
- Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis
- (2011) Ruth J. Napier et al. Cell Host & Microbe
- Effects of Mycobacterium tuberculosis ESAT-6/CFP-10 Fusion Protein on the Autophagy Function of Mouse Macrophages
- (2011) Lei Zhang et al. DNA AND CELL BIOLOGY
- Autophagy in immunity and inflammation
- (2011) Beth Levine et al. NATURE
- Phosphodiesterase-4 Inhibition Alters Gene Expression and Improves Isoniazid – Mediated Clearance of Mycobacterium tuberculosis in Rabbit Lungs
- (2011) Selvakumar Subbian et al. PLoS Pathogens
- Antimicrobial Peptides in Innate Immunity against Mycobacteria
- (2011) Dong-Min Shin et al. Immune Network
- The effect of vitamin A and zinc supplementation on treatment outcomes in pulmonary tuberculosis: a randomized controlled trial
- (2010) Marianne E Visser et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Organelle Membrane Proteomics Reveals Differential Influence of Mycobacterial Lipoglycans on Macrophage Phagosome Maturation and Autophagosome Accumulation
- (2010) Wenqing Shui et al. JOURNAL OF PROTEOME RESEARCH
- BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: A review
- (2010) Xin An et al. LEUKEMIA RESEARCH
- The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights
- (2010) Agnes E. Coutinho et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Randomized controlled trial of zinc and vitamin A as co-adjuvants for the treatment of pulmonary tuberculosis
- (2010) Lovett Lawson et al. TROPICAL MEDICINE & INTERNATIONAL HEALTH
- Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling
- (2010) Dong-Min Shin et al. PLoS Pathogens
- Phenylbutyrate Induces Antimicrobial Peptide Expression
- (2009) J. Steinmann et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin
- (2009) Jae-Min Yuk et al. Cell Host & Microbe
- Mutation in the Transcriptional Regulator PhoP Contributes to Avirulence of Mycobacterium tuberculosis H37Ra Strain
- (2008) Jong Seok Lee et al. Cell Host & Microbe
- Mycobacterium tuberculosis Prevents Inflammasome Activation
- (2008) Sharon S. Master et al. Cell Host & Microbe
- Role of the dosR-dosS Two-Component Regulatory System in Mycobacterium tuberculosis Virulence in Three Animal Models
- (2008) P. J. Converse et al. INFECTION AND IMMUNITY
- Control of M. tuberculosis ESAT-6 Secretion and Specific T Cell Recognition by PhoP
- (2008) Wafa Frigui et al. PLoS Pathogens
- Mycobacterial persistence requires the utilization of host cholesterol
- (2008) A. K. Pandey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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