Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases
出版年份 2020 全文链接
标题
Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-05-27
DOI
10.3389/fphar.2020.00730
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer
- (2019) Magdalena Grill et al. Scientific Reports
- Conventional therapy for moderate to severe inflammatory bowel disease: A systematic literature review
- (2019) Adérson Omar Mourão Cintra Damião et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Role of PPAR receptor in different diseases and their ligands: Physiological importance and clinical implications
- (2019) Agha Zeeshan Mirza et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
- (2019) Jiao Peng et al. Frontiers in Pharmacology
- Flos Abelmoschus manihot extract attenuates DSS-induced colitis by regulating gut microbiota and Th17/Treg balance
- (2019) Wei Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Modern use of 5-aminosalicylic acid compounds for ulcerative colitis
- (2019) Catherine Le Berre et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Clinical Pharmacokinetics and Pharmacodynamics of Infliximab in the Treatment of Inflammatory Bowel Disease
- (2018) Amy Hemperly et al. CLINICAL PHARMACOKINETICS
- Mechanistic Understanding of Herbal Therapy in Inflammatory Bowel Disease
- (2018) Luqing Zhao et al. CURRENT PHARMACEUTICAL DESIGN
- The endogenous bioactive lipid prostaglandin D2-glycerol ester reduces murine colitis via DP1 and PPARγ receptors
- (2018) Mireille Alhouayek et al. FASEB JOURNAL
- Tropisetron attenuates lipopolysaccharide induced neuroinflammation by inhibiting NF-κB and SP/NK1R signaling pathway
- (2018) Yan YU et al. JOURNAL OF NEUROIMMUNOLOGY
- Magnolol treatment attenuates dextran sulphate sodium-induced murine experimental colitis by regulating inflammation and mucosal damage
- (2018) Peng Shen et al. LIFE SCIENCES
- 5-aminosalicylic acid improves lipid profile in mice fed a high-fat cholesterol diet through its dual effects on intestinal PPARγ and PPARα
- (2018) Zheng Wang et al. PLoS One
- Portulaca Extract Attenuates Development of Dextran Sulfate Sodium Induced Colitis in Mice through Activation of PPARγ
- (2018) Rui Kong et al. PPAR Research
- Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism
- (2018) Jie Zheng et al. STRUCTURE
- The role of obesity in inflammatory bowel disease
- (2018) Roxane Kreuter et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A partial agonist for retinoid X receptor mitigates experimental colitis
- (2018) Masayoshi Onuki et al. INTERNATIONAL IMMUNOLOGY
- A structural mechanism for directing corepressor-selective inverse agonism of PPARγ
- (2018) Richard Brust et al. Nature Communications
- Dietary n-3 polyunsaturated fatty acids ameliorate Crohn's disease in rats by modulating the expression of PPAR-γ/NFAT
- (2017) Jiayin Yao et al. Molecular Medicine Reports
- Environmental triggers in IBD: a review of progress and evidence
- (2017) Ashwin N. Ananthakrishnan et al. Nature Reviews Gastroenterology & Hepatology
- Role of glycogen synthase kinase-3β and PPAR-γ on epithelial-to-mesenchymal transition in DSS-induced colorectal fibrosis
- (2017) Jacopo Di Gregorio et al. PLoS One
- rSj16 Protects against DSS-Induced Colitis by Inhibiting the PPAR-α Signaling Pathway
- (2017) Lifu Wang et al. Theranostics
- New Frontiers in Genetics, Gut Microbiota, and Immunity: A Rosetta Stone for the Pathogenesis of Inflammatory Bowel Disease
- (2017) Mingxia Zhou et al. Biomed Research International
- Emerging oral targeted therapies in inflammatory bowel diseases: opportunities and challenges
- (2017) Marcel Vetter et al. Therapeutic Advances in Gastroenterology
- Interactions between Intestinal Microbiota and Host Immune Response in Inflammatory Bowel Disease
- (2017) Ming Zhang et al. Frontiers in Immunology
- Oleoylethanolamide prevents neuroimmune HMGB1/TLR4/NF-kB danger signaling in rat frontal cortex and depressive-like behavior induced by ethanol binge administration
- (2016) María Antón et al. ADDICTION BIOLOGY
- Adelmidrol, a palmitoylethanolamide analogue, as a new pharmacological treatment for the management of acute and chronic inflammation
- (2016) Daniela Impellizzeri et al. BIOCHEMICAL PHARMACOLOGY
- Anti-inflammatory effects of an oxylipin-containing lyophilised biomass from a microalga in a murine recurrent colitis model
- (2016) Javier Ávila-Román et al. BRITISH JOURNAL OF NUTRITION
- Fatty acids, eicosanoids and PPAR gamma
- (2016) Rachel Marion-Letellier et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Involvement of PPARγ in the protective action of tropisetron in an experimental model of ulcerative colitis
- (2016) Reza Rahimian et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Novel PPARγ Modulator GED-0507-34 Levo Ameliorates Inflammation-driven Intestinal Fibrosis
- (2016) Silvia Speca et al. INFLAMMATORY BOWEL DISEASES
- The gastrointestinal tract - a central organ of cannabinoid signaling in health and disease
- (2016) C. Hasenoehrl et al. NEUROGASTROENTEROLOGY AND MOTILITY
- High-fat diet modifies the PPAR-γ pathway leading to disruption of microbial and physiological ecosystem in murine small intestine
- (2016) Julie Tomas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Voluntary exercise protects against ulcerative colitis by up-regulating glucocorticoid-mediated PPAR-γactivity in the colon in mice
- (2015) W.-X. Liu et al. Acta Physiologica
- Voluntary exercise prevents colonic inflammation in high-fat diet-induced obese mice by up-regulating PPAR-γ activity
- (2015) Wei-Xin Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Stimulation of nuclear receptor peroxisome proliferator-activated receptor-γ limits NF-κB-dependent inflammation in mouse cystic fibrosis biliary epithelium
- (2015) Roberto Scirpo et al. HEPATOLOGY
- A Novel Peroxisome Proliferator-activated Receptor (PPAR)γ Agonist 2-Hydroxyethyl 5-chloro-4,5-didehydrojasmonate Exerts Anti-Inflammatory Effects in Colitis
- (2015) Jieun Choo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epidemiology and risk factors for IBD
- (2015) Ashwin N. Ananthakrishnan Nature Reviews Gastroenterology & Hepatology
- Dietary n-3 PUFA Protects Mice from Con A Induced Liver Injury by Modulating Regulatory T Cells and PPAR-γ Expression
- (2015) Min Lian et al. PLoS One
- Establishing the Role of PPARβ/δ in Carcinogenesis
- (2015) Jeffrey M. Peters et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent
- (2014) Francesca Borrelli et al. BRITISH JOURNAL OF PHARMACOLOGY
- Peroxisome Proliferator-Activated Receptors Family Is Involved in the Response to Treatment and Mild Clinical Course in Patients with Ulcerative Colitis
- (2014) J. K. Yamamoto-Furusho et al. DISEASE MARKERS
- Intestinal steroidogenesis controls PPARγ expression in the colon and is impaired during ulcerative colitis
- (2014) Guillaume Bouguen et al. GUT
- Chitinase-like proteins promote IL-17-mediated neutrophilia in a tradeoff between nematode killing and host damage
- (2014) Tara E Sutherland et al. NATURE IMMUNOLOGY
- Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications - a review
- (2014) Bogna Grygiel-Górniak Nutrition Journal
- PPAR-Gamma in Ulcerative Colitis: A Novel Target for Intervention
- (2013) Benjamin Bertin et al. CURRENT DRUG TARGETS
- Peroxisome proliferator-activated receptor δ
- (2013) Lazar A. Bojic et al. CURRENT OPINION IN LIPIDOLOGY
- Long-term intake of dietary fat and risk of ulcerative colitis and Crohn's disease
- (2013) Ashwin N Ananthakrishnan et al. GUT
- Polyunsaturated Fatty Acids in Inflammatory Bowel Diseases
- (2013) Rachel Marion-Letellier et al. INFLAMMATORY BOWEL DISEASES
- Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma
- (2013) Irene Paterniti et al. Journal of Neuroinflammation
- PPARγ signaling and metabolism: the good, the bad and the future
- (2013) Maryam Ahmadian et al. NATURE MEDICINE
- Crohn's disease
- (2012) Daniel C Baumgart et al. LANCET
- Ulcerative Colitis Impairs the Acylethanolamide-Based Anti-Inflammatory System Reversal by 5-Aminosalicylic Acid and Glucocorticoids
- (2012) Juan Suárez et al. PLoS One
- Infliximab modifies mesenteric adipose tissue alterations and intestinal inflammation in rats with TNBS-induced colitis
- (2012) Thayane Rodrigues Leite Clemente et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- An Evidence-Based Systematic Review on Medical Therapies for Inflammatory Bowel Disease
- (2011) Nicholas J Talley et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Efficacy of Immunosuppressive Therapy for Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
- (2011) Khurram J Khan et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Efficacy of Biological Therapies in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis
- (2011) Alexander C Ford et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Efficacy of 5-Aminosalicylates in Ulcerative Colitis: Systematic Review and Meta-Analysis
- (2011) Alexander C Ford et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Antibiotic Therapy in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis
- (2011) Khurram J Khan et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Epidemiology and Natural History of Inflammatory Bowel Diseases
- (2011) Jacques Cosnes et al. GASTROENTEROLOGY
- Antibodies Against Tumor Necrosis Factor (TNF) Induce T-Cell Apoptosis in Patients With Inflammatory Bowel Diseases via TNF Receptor 2 and Intestinal CD14+ Macrophages
- (2011) Raja Atreya et al. GASTROENTEROLOGY
- Role of genetic and environmental factors in British twins with inflammatory bowel disease
- (2011) Siew C. Ng et al. INFLAMMATORY BOWEL DISEASES
- Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolism
- (2011) A. W. Thomas et al. JOURNAL OF APPLIED PHYSIOLOGY
- The endogenous cannabinoid system in the gut of patients with inflammatory bowel disease
- (2011) A Di Sabatino et al. Mucosal Immunology
- Ulcerative Colitis
- (2011) Silvio Danese et al. NEW ENGLAND JOURNAL OF MEDICINE
- Optimizing clinical use of mesalazine (5-aminosalicylic acid) in inflammatory bowel disease
- (2011) Chadwick Williams et al. Therapeutic Advances in Gastroenterology
- Fibrates, Glitazones, and Peroxisome Proliferator–Activated Receptors
- (2010) Fanny Lalloyer et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Molecular basis for gene-specific transactivation by nuclear receptors
- (2010) Mads M. Aagaard et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Peroxisome proliferator-activated receptor-gamma (PPAR-γ) expression is downregulated in patients with active ulcerative colitis
- (2010) Jesús K. Yamamoto-Furusho et al. INFLAMMATORY BOWEL DISEASES
- PPARα contributes to colonic protection in mice with DSS-induced colitis
- (2010) Yasu-Taka Azuma et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Immunoregulatory mechanisms of macrophage PPAR-γ in mice with experimental inflammatory bowel disease
- (2010) R Hontecillas et al. Mucosal Immunology
- Peroxisome proliferator-activated receptor gamma activation is required for maintenance of innate antimicrobial immunity in the colon
- (2010) L. Peyrin-Biroulet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Coactivators in PPAR-Regulated Gene Expression
- (2010) Navin Viswakarma et al. PPAR Research
- PPAR-αContributes to the Anti-Inflammatory Activity of Verbascoside in a Model of Inflammatory Bowel Disease in Mice
- (2010) Emanuela Esposito et al. PPAR Research
- Peroxisome Proliferator-Activated Receptor γ and Cardiovascular Diseases
- (2009) Hiroyuki Takano et al. CIRCULATION JOURNAL
- Effects of verbascoside biotechnologically produced by Syringa vulgaris plant cell cultures in a rodent model of colitis
- (2009) Emanuela Mazzon et al. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
- Inflammatory Bowel Disease
- (2009) Clara Abraham et al. NEW ENGLAND JOURNAL OF MEDICINE
- Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation
- (2009) C. Solorzano et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-α MODULATES THE ANTI-INFLAMMATORY EFFECT OF GLUCOCORTICOIDS IN A MODEL OF INFLAMMATORY BOWEL DISEASE IN MICE
- (2009) Luisa Riccardi et al. SHOCK
- Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors
- (2008) Martin A. Storr et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- PPAR-γ agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-β
- (2008) Toru Kawai et al. LABORATORY INVESTIGATION
- The endogenous fatty acid amide, palmitoylethanolamide, has anti-allodynic and anti-hyperalgesic effects in a murine model of neuropathic pain: involvement of CB1, TRPV1 and PPARγ receptors and neurotrophic factors
- (2008) Barbara Costa et al. PAIN
- Enterococcus faecalis from newborn babies regulate endogenous PPAR activity and IL-10 levels in colonic epithelial cells
- (2008) A. Are et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evidence for the involvement of infectious agents in the pathogenesis of Crohn’s disease
- (2008) Gert De Hertogh WORLD JOURNAL OF GASTROENTEROLOGY
- Is There a Role for Fibrates in the Management of Dyslipidemia in the Metabolic Syndrome?
- (2007) Philip J. Barter et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- PPARα agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages
- (2007) E-L Paukkeri et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cellular and molecular mechanisms of fibrosis
- (2007) TA Wynn JOURNAL OF PATHOLOGY
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