CCT020312 Inhibits Triple-Negative Breast Cancer Through PERK Pathway-Mediated G1 Phase Cell Cycle Arrest and Apoptosis
出版年份 2020 全文链接
标题
CCT020312 Inhibits Triple-Negative Breast Cancer Through PERK Pathway-Mediated G1 Phase Cell Cycle Arrest and Apoptosis
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-05-19
DOI
10.3389/fphar.2020.00737
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Endoplasmic Reticulum Stress Promotes Liver Cancer Cells to Release Exosomal miR-23a-3p and Up-regulate PD-L1 Expression in Macrophages
- (2019) Jiatao Liu et al. HEPATOLOGY
- Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies
- (2019) Yi-Zhou Jiang et al. CANCER CELL
- Consideration of breast cancer subtype in targeting the androgen receptor
- (2019) Clasina M. Venema et al. PHARMACOLOGY & THERAPEUTICS
- Activation of PERK-eIF2α-ATF4 pathway contributes to diabetic hepatotoxicity: Attenuation of ER stress by Morin
- (2019) Vivek Kumar Pandey et al. CELLULAR SIGNALLING
- Inhibition of protein phosphatase 1 stimulates noncanonical ER stress eIF2α activation to enhance fisetin-induced chemosensitivity in HDAC inhibitor-resistant hepatocellular carcinoma cells
- (2019) Liu et al. Cancers
- Genistein upregulates cyclin D1 and CDK4 expression and promotes the proliferation of ovarian cancer OVCAR-5 cells
- (2019) Yali Wang et al. CLINICA CHIMICA ACTA
- Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis
- (2019) Natalia Siwecka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma
- (2019) Shatha AbuHammad et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The PI3K/AKT/mTOR and CDK4/6 Pathways in Endocrine Resistant HR+/HER2− Metastatic Breast Cancer: Biological Mechanisms and New Treatments
- (2019) Daniele Presti et al. Cancers
- Eribulin Synergistically Increases Anti-Tumor Activity of an mTOR Inhibitor by Inhibiting pAKT/pS6K/pS6 in Triple Negative Breast Cancer
- (2019) Wei Wen et al. Cells
- YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways
- (2019) Qun Chen et al. BRITISH JOURNAL OF CANCER
- Recent treatment progress of triple negative breast cancer
- (2019) Yang Chang-Qing et al. PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
- PERK Regulates Glioblastoma Sensitivity to ER Stress While Promoting Radiation Resistance
- (2018) David YA Dadey et al. MOLECULAR CANCER RESEARCH
- Overexpression of miR-1283 inhibits cell proliferation and invasion of glioma cells by targeting ATF4
- (2018) Hao Chen et al. ONCOLOGY RESEARCH
- The Unfolded Protein Response in Breast Cancer
- (2018) Eoghan McGrath et al. Cancers
- Celastrol induces ubiquitin-dependent degradation of mTOR in breast cancer cells
- (2018) Xiaoli Li et al. OncoTargets and Therapy
- GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
- (2017) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- SGK3 sustains ERα signaling and drives acquired aromatase inhibitor resistance through maintaining endoplasmic reticulum homeostasis
- (2017) Yuanzhong Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The integrated stress response
- (2016) Karolina Pakos‐Zebrucka et al. EMBO REPORTS
- Endoplasmic Reticulum (ER) Stress Induces Sirtuin 1 (SIRT1) Expression via the PI3K-Akt-GSK3β Signaling Pathway and Promotes Hepatocellular Injury
- (2015) Tomoaki Koga et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tanshinone IIA Inhibits HIF-1α and VEGF Expression in Breast Cancer Cells via mTOR/p70S6K/RPS6/4E-BP1 Signaling Pathway
- (2015) Guobing Li et al. PLoS One
- Evidence for eIF2α phosphorylation-independent effects of GSK2656157, a novel catalytic inhibitor of PERK with clinical implications
- (2014) Jothi Krishnamoorthy et al. CELL CYCLE
- Characterization of a Novel PERK Kinase Inhibitor with Antitumor and Antiangiogenic Activity
- (2013) C. Atkins et al. CANCER RESEARCH
- ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
- (2013) Jaeseok Han et al. NATURE CELL BIOLOGY
- PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation
- (2012) E. Bobrovnikova-Marjon et al. MOLECULAR AND CELLULAR BIOLOGY
- Mechanism-Based Screen for G1/S Checkpoint Activators Identifies a Selective Activator of EIF2AK3/PERK Signalling
- (2012) Simon R. Stockwell et al. PLoS One
- Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
- (2012) Christian Appenzeller-Herzog et al. TRENDS IN CELL BIOLOGY
- Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia
- (2011) Tomasz Rzymski et al. CELL CYCLE
- ATF4-dependent transcription mediates signaling of amino acid limitation
- (2009) Michael S. Kilberg et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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