Chaperone duality: the role of extracellular and intracellular HSP70 as a biomarker of endothelial dysfunction in the development of atherosclerosis

Cell-surface HSP70 associates with thrombomodulin in endothelial cells

(2019) Thaís L. S. Araujo et al.   CELL STRESS & CHAPERONES

Effects of High-Fat Diet on eHSP72 and Extra-to-Intracellular HSP70 Levels in Mice Submitted to Exercise under Exposure to Fine Particulate Matter

(2019) Iberê Machado Kostrycki et al.   Journal of Diabetes Research

Ovariectomy predisposes female rats to fine particulate matter exposure’s effects by altering metabolic, oxidative, pro-inflammatory, and heat-shock protein levels

(2019) Pauline Brendler Goettems-Fiorin et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

The Hsp70 chaperone network

(2019) Rina Rosenzweig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

4-HNE Induces Apoptosis of Human Retinal Pigment Epithelial Cells by Modifying HSP70

(2019) Lei-lei Yang et al.   Current Medical Science

Age-Related Vascular Changes Affect Turbulence in Aortic Blood Flow

(2018) Hojin Ha et al.   Frontiers in Physiology

Chronic whole-body heat treatment relieves atherosclerotic lesions, cardiovascular and metabolic abnormalities, and enhances survival time restoring the anti-inflammatory and anti-senescent heat shock response in mice

(2018) Maciel Alencar Bruxel et al.   BIOCHIMIE

Dynamic Phosphorylation of the C Terminus of Hsp70 Regulates the Mitochondrial Import of SOD2 and Redox Balance

(2018) Sara Zemanovic et al.   Cell Reports

Membrane Hsp70—A Novel Target for the Isolation of Circulating Tumor Cells After Epithelial-to-Mesenchymal Transition

(2018) Stephanie Breuninger et al.   Frontiers in Oncology

Nitric oxide-heat shock protein axis in menopausal hot flushes: neglected metabolic issues of chronic inflammatory diseases associated with deranged heat shock response

(2017) Antônio Azambuja Miragem et al.   HUMAN REPRODUCTION UPDATE

Exercise Training under Exposure to Low Levels of Fine Particulate Matter: Effects on Heart Oxidative Stress and Extra-to-Intracellular HSP70 Ratio

(2017) Aline Sfalcin Mai et al.   Oxidative Medicine and Cellular Longevity

Metabolic Regulation of Angiogenesis in Diabetes and Aging

(2017) Naoki Sawada et al.   PHYSIOLOGY

Diet-induced elevation of circulating HSP70 may trigger cell adhesion and promote the development of atherosclerosis in rats

(2016) Fang Xie et al.   CELL STRESS & CHAPERONES

HSP70 in human polymorphonuclear and mononuclear leukocytes: comparison of the protein content and transcriptional activity of HSPA genes

(2016) Anna A. Boyko et al.   CELL STRESS & CHAPERONES

The human HSP70 family of chaperones: where do we stand?

(2016) Jürgen Radons   CELL STRESS & CHAPERONES

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

(2016) Michael A. Gimbrone et al.   CIRCULATION RESEARCH

Heat shock protein 70 and antibodies to heat shock protein 60 are associated with cerebrovascular atherosclerosis

(2016) Ružica Galović et al.   CLINICAL BIOCHEMISTRY

Fine particulate matter potentiates type 2 diabetes development in high-fat diet-treated mice: stress response and extracellular to intracellular HSP70 ratio analysis

(2016) Pauline Brendler Goettems-Fiorin et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Endothelial nitric oxide synthase induces heat shock protein HSPA6 (HSP70B′) in human arterial smooth muscle cells

(2016) K.J.A. McCullagh et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Membrane-bound heat shock proteins facilitate the uptake of dying cells and cross-presentation of cellular antigen

(2015) Haiyan Zhu et al.   APOPTOSIS

The regulatory roles of NADPH oxidase, intra- and extra-cellular HSP70 in pancreatic islet function, dysfunction and diabetes

(2015) Mauricio Krause et al.   CLINICAL SCIENCE

Biomarkers of Subclinical Atherosclerosis and Natural Products as Complementary Alternative Medicine

(2015) Jonatas Zeni Klafke et al.   CURRENT PHARMACEUTICAL DESIGN

Targeting HSP90 Ameliorates Nephropathy and Atherosclerosis Through Suppression of NF-κB and STAT Signaling Pathways in Diabetic Mice

(2015) Iolanda Lazaro et al.   DIABETES

The Chaperone Balance Hypothesis: The Importance of the Extracellular to Intracellular HSP70 Ratio to Inflammation-Driven Type 2 Diabetes, the Effect of Exercise, and the Implications for Clinical Management

(2015) Mauricio Krause et al.   MEDIATORS OF INFLAMMATION

Vascular oxidative stress, nitric oxide and atherosclerosis

(2014) Huige Li et al.   ATHEROSCLEROSIS

Endothelial caveolin-1 plays a major role in the development of atherosclerosis

(2014) Stephanos Pavlides et al.   CELL AND TISSUE RESEARCH

The oxidation of HSP70 is associated with functional impairment and lack of stimulatory capacity

(2014) Marcelo Sartori Grunwald et al.   CELL STRESS & CHAPERONES

Hsp70 Translocates into the Plasma Membrane after Stress and Is Released into the Extracellular Environment in a Membrane-Associated Form that Activates Macrophages

(2014) V. L. Vega et al.   JOURNAL OF IMMUNOLOGY

Role of alpha- and beta-adrenoreceptors in rat monocyte/macrophage function at rest and acute exercise

(2014) Juliane da Silva Rossato et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

HSPA12B attenuates cardiac dysfunction and remodelling after myocardial infarction through an eNOS-dependent mechanism

(2013) Jingjin Li et al.   CARDIOVASCULAR RESEARCH

Hsp70 regulation on Nox4/p22phox and cytoskeletal integrity as an effect of losartan in vascular smooth muscle cells

(2013) Andrea Fernanda Gil Lorenzo et al.   CELL STRESS & CHAPERONES

Evidence of a role for both anti-Hsp70 antibody and endothelial surface membrane Hsp70 in atherosclerosis

(2013) Xue Leng et al.   CELL STRESS & CHAPERONES

Heat Shock Prevents Insulin Resistance-Induced Vascular Complications by Augmenting Angiotensin-(1-7) Signaling

(2013) P. A. Karpe et al.   DIABETES

Heat Shock Proteins 60 and 70 Specific Proinflammatory and Cytotoxic Response of CD4+CD28nullCells in Chronic Kidney Disease

(2013) Ashok K. Yadav et al.   MEDIATORS OF INFLAMMATION

Extracellular Heat Shock Proteins

(2013) Antonio De Maio et al.   SHOCK

Opposing Actions of Heat Shock Protein 90 and 70 Regulate Nicotinamide Adenine Dinucleotide Phosphate Oxidase Stability and Reactive Oxygen Species Production

(2012) Feng Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

HSP90 inhibition by 17-DMAG attenuates oxidative stress in experimental atherosclerosis

(2012) Julio Madrigal-Matute et al.   CARDIOVASCULAR RESEARCH

Ferruccio Ritossa’s scientific legacy 50 years after his discovery of the heat shock response: a new view of biology, a new society, and a new journal

(2012) Antonio De Maio et al.   CELL STRESS & CHAPERONES

Divergence of intracellular and extracellular HSP72 in type 2 diabetes: does fat matter?

(2012) Josianne Rodrigues-Krause et al.   CELL STRESS & CHAPERONES

HSP70 increases extracellular matrix production by human vascular smooth muscle through TGF-β1 up-regulation

(2012) Marta González-Ramos et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

HSP70 expression: does it a novel fatigue signalling factor from immune system to the brain?

(2011) Thiago Gomes Heck et al.   CELL BIOCHEMISTRY AND FUNCTION

SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans

(2011) Anthony J. Donato et al.   JOURNAL OF PHYSIOLOGY-LONDON

Plasma levels of Hsp70 and anti-Hsp70 antibody predict risk of acute coronary syndrome

(2010) Xiaomin Zhang et al.   CELL STRESS & CHAPERONES

Serum level of soluble Hsp70 is associated with vascular calcification

(2010) Miklós Krepuska et al.   CELL STRESS & CHAPERONES

Extracellular heat shock proteins, cellular export vesicles, and the Stress Observation System: A form of communication during injury, infection, and cell damage

(2010) Antonio De Maio   CELL STRESS & CHAPERONES

Interleukin-6 inhibits endothelial nitric oxide synthase activation and increases endothelial nitric oxide synthase binding to stabilized caveolin-1 in human vascular endothelial cells

(2010) Ming-Jui Hung et al.   JOURNAL OF HYPERTENSION

Hyperlipidemia induces endothelial-derived foam cells in culture

(2010) Luminita Ivan et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Heat shock protein 70 is secreted from endothelial cells by a non-classical pathway involving exosomes

(2009) Rui Zhan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The structural biochemistry of the superoxide dismutases

(2009) J.J.P. Perry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Hsp70 expression in monocytes from patients with peripheral arterial disease and healthy controls

(2009) Jacqueline Madden et al.   CELL BIOLOGY AND TOXICOLOGY

Guidelines for the nomenclature of the human heat shock proteins

(2008) Harm H. Kampinga et al.   CELL STRESS & CHAPERONES