Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype
出版年份 2020 全文链接
标题
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype
作者
关键词
-
出版物
Cell Death & Disease
Volume 11, Issue 5, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-05-15
DOI
10.1038/s41419-020-2565-2
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- NLRP3-dependent pyroptosis is required for HIV-1 gp120-induced neuropathology
- (2019) Xiaolong He et al. Cellular & Molecular Immunology
- A Kv1.3 channel-specific blocker alleviates neurological impairment through inhibiting T-cell activation in experimental autoimmune encephalomyelitis
- (2018) Xiao-Lu Yuan et al. CNS Neuroscience & Therapeutics
- Anticonvulsant agent DPP4 inhibitor sitagliptin downregulates CXCR3/RAGE pathway on seizure models
- (2018) Yunli Liu et al. EXPERIMENTAL NEUROLOGY
- Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
- (2018) Seung Pil Yun et al. NATURE MEDICINE
- NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease
- (2017) Jun Yin et al. MOLECULAR NEUROBIOLOGY
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y 1 Receptor Downregulation
- (2017) Youichi Shinozaki et al. Cell Reports
- An interferon-β-resistant and NLRP3 inflammasome–independent subtype of EAE with neuronal damage
- (2016) Makoto Inoue et al. NATURE NEUROSCIENCE
- Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models
- (2016) Michael J. D. Daniels et al. Nature Communications
- Cognition and fatigue in patients with relapsing multiple sclerosis treated by subcutaneous interferon β-1a: an observational study SKORE
- (2016) Yvonne Benešová et al. Therapeutic Advances in Neurological Disorders
- Neuroinflammatory TNFα Impairs Memory via Astrocyte Signaling
- (2015) Samia Habbas et al. CELL
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- NFκB-Activated Astroglial Release of Complement C3 Compromises Neuronal Morphology and Function Associated with Alzheimer’s Disease
- (2015) Hong Lian et al. NEURON
- Hippocampal function is compromised in an animal model of multiple sclerosis
- (2015) T. Novkovic et al. NEUROSCIENCE
- The role of inflammasome in Alzheimer's disease
- (2014) Li Liu et al. AGEING RESEARCH REVIEWS
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Altered cognitive-emotional behavior in early experimental autoimmune encephalitis – Cytokine and hormonal correlates
- (2013) Shaona Acharjee et al. BRAIN BEHAVIOR AND IMMUNITY
- A critical role of astrocyte-mediated nuclear factor-κB-dependent inflammation in Huntington's disease
- (2013) Han-Yun Hsiao et al. HUMAN MOLECULAR GENETICS
- Interleukin-1 Alters Glutamate Transmission at Purkinje Cell Synapses in a Mouse Model of Multiple Sclerosis
- (2013) G. Mandolesi et al. JOURNAL OF NEUROSCIENCE
- Effects of central and peripheral inflammation on hippocampal synaptic plasticity
- (2013) Massimiliano Di Filippo et al. NEUROBIOLOGY OF DISEASE
- Oligomers of beta-amyloid protein (Aβ1-42) induce the activation of cyclooxygenase-2 in astrocytes via an interaction with interleukin-1beta, tumour necrosis factor-alpha, and a nuclear factor kappa-B mechanism in the rat brain
- (2012) I. Carrero et al. EXPERIMENTAL NEUROLOGY
- Serum levels of interleukin (IL)-18, IL-23 and IL-17 in Chinese patients with multiple sclerosis
- (2012) Ying-Chun Chen et al. JOURNAL OF NEUROIMMUNOLOGY
- Microglial activation induced by brain trauma is suppressed by post-injury treatment with a PARP inhibitor
- (2012) Joana C d’Avila et al. Journal of Neuroinflammation
- Role of P2X7 Receptor-Mediated IL-18/IL-18R Signaling in Morphine Tolerance: Multiple Glial-Neuronal Dialogues in the Rat Spinal Cord
- (2012) Meng-Ling Chen et al. JOURNAL OF PAIN
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis
- (2012) M. Inoue et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cognition in multiple sclerosis
- (2011) Dawn W Langdon CURRENT OPINION IN NEUROLOGY
- Development of a Method for the Purification and Culture of Rodent Astrocytes
- (2011) Lynette C. Foo et al. NEURON
- In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects
- (2010) M. Faideau et al. HUMAN MOLECULAR GENETICS
- NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses
- (2010) D. Gris et al. JOURNAL OF IMMUNOLOGY
- Interleukin 18 in the CNS
- (2010) Silvia Alboni et al. Journal of Neuroinflammation
- Hippocampal CA1 atrophy and synaptic loss during experimental autoimmune encephalomyelitis, EAE
- (2010) Marina O Ziehn et al. LABORATORY INVESTIGATION
- Relevance of cognitive deterioration in early relapsing-remitting MS: a 3-year follow-up study
- (2010) Maria P Amato et al. Multiple Sclerosis Journal
- Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity
- (2009) Javier Palazuelos et al. BRAIN
- The analysis of IL-1 beta and its naturally occurring inhibitors in multiple sclerosis: The elevation of IL-1 receptor antagonist and IL-1 receptor type II after steroid therapy
- (2009) Irena Dujmovic et al. JOURNAL OF NEUROIMMUNOLOGY
- A role for galanin in human and experimental inflammatory demyelination
- (2009) D. C. Wraith et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Japanese Encephalitis Virus infection induces IL-18 and IL-1β in microglia and astrocytes: Correlation with in vitro cytokine responsiveness of glial cells and subsequent neuronal death
- (2008) Sulagna Das et al. JOURNAL OF NEUROIMMUNOLOGY
- Interleukin-18-Mediated Microglia/Astrocyte Interaction in the Spinal Cord Enhances Neuropathic Pain Processing after Nerve Injury
- (2008) K. Miyoshi et al. JOURNAL OF NEUROSCIENCE
- Cognitive impairment in multiple sclerosis
- (2008) F Patti Multiple Sclerosis Journal
- The NALP3 inflammasome is involved in the innate immune response to amyloid-β
- (2008) Annett Halle et al. NATURE IMMUNOLOGY
- Neuroinflammation and synaptic plasticity: theoretical basis for a novel, immune-centred, therapeutic approach to neurological disorders
- (2008) Massimiliano Di Filippo et al. TRENDS IN PHARMACOLOGICAL SCIENCES
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