MSCs ameliorate hepatocellular apoptosis mediated by PINK1-dependent mitophagy in liver ischemia/reperfusion injury through AMPKα activation

Crosstalk between Connexin 32 and mitochondrial apoptotic signaling pathway plays a pivotal role in renal ischemia reperfusion–induced acute kidney injury

(2018) Chaojin Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury

(2018) Chengyuan Tang et al.   Autophagy

Resolvin D1 attenuates liver ischaemia/reperfusion injury through modulating thioredoxin 2-mediated mitochondrial quality control

(2018) Jung-Woo Kang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of Mitochondrial Dysfunction and Reactive Oxygen Species in Mediating Hypertension in the Reduced Uterine Perfusion Pressure Rat Model of Preeclampsia

(2018) Venkata Ramana Vaka et al.   HYPERTENSION

IDH2 deficiency increases the liver susceptibility to ischemia-reperfusion injury via increased mitochondrial oxidative injury

(2018) Sang Jun Han et al.   Redox Biology

Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration

(2018) Yu Song et al.   Redox Biology

Allogeneic bone marrow-derived mesenchymal stromal cells for hepatitis B virus-related acute-on-chronic liver failure: A randomized controlled trial

(2017) Bing-liang Lin et al.   HEPATOLOGY

Infusion of mesenchymal stromal cells after deceased liver transplantation: A phase I–II, open-label, clinical study

(2017) Olivier Detry et al.   JOURNAL OF HEPATOLOGY

Genipin protects the liver from ischemia/reperfusion injury by modulating mitochondrial quality control

(2017) Jun-Kyu Shin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nanosized UCMSC-derived extracellular vesicles but not conditioned medium exclusively inhibit the inflammatory response of stimulated T cells: implications for nanomedicine

(2017) Marta Monguió-Tortajada et al.   Theranostics

A Pilot Study of Mesenchymal Stem Cell Therapy for Acute Liver Allograft Rejection

(2017) Ming Shi et al.   Stem Cells Translational Medicine

AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation

(2017) Bei Wang et al.   CIRCULATION RESEARCH

Transplantation with autologous bone marrow-derived mesenchymal stem cells for alcoholic cirrhosis: Phase 2 trial

(2016) Ki Tae Suk et al.   HEPATOLOGY

Melatonin pretreatment enhances the therapeutic effects of exogenous mitochondria against hepatic ischemia-reperfusion injury in rats through suppression of mitochondrial permeability transition

(2016) Hong-Hwa Chen et al.   JOURNAL OF PINEAL RESEARCH

Mitochondria-Targeted Antioxidants: Future Perspectives in Kidney Ischemia Reperfusion Injury

(2016) Aleksandra Kezic et al.   Oxidative Medicine and Cellular Longevity

The Dichotomy of Endoplasmic Reticulum Stress Response in Liver Ischemia-Reperfusion Injury

(2016) Haomming Zhou et al.   TRANSPLANTATION

Deciphering the Molecular Signals of PINK1/Parkin Mitophagy

(2016) Thanh N. Nguyen et al.   TRENDS IN CELL BIOLOGY

Hyperglycemia Abrogates Ischemic Postconditioning Cardioprotection by Impairing AdipoR1/Caveolin-3/STAT3 Signaling in Diabetic Rats

(2015) Haobo Li et al.   DIABETES

Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy

(2015) Weili Tian et al.   FEBS LETTERS

Adiponectin ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction by concomitantly activating Nrf2 and Brg1

(2015) Haobo Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial delivery of Coenzyme Q 10 via systemic administration using a MITO-Porter prevents ischemia/reperfusion injury in the mouse liver

(2015) Yuma Yamada et al.   JOURNAL OF CONTROLLED RELEASE

Dexmedetomidine protects against apoptosis induced by hypoxia/reoxygenation through the inhibition of gap junctions in NRK-52E cells

(2015) Chenfang Luo et al.   LIFE SCIENCES

Hypoxia preconditioning induced HIF-1α promotes glucose metabolism and protects mitochondria in liver I/R injury

(2015) Zhuang Zhuonan et al.   Clinics and Research in Hepatology and Gastroenterology

Plasmacytoid dendritic cell-derived IFN-α promotes murine liver ischemia/reperfusion injury by induction of hepatocyte IRF-1

(2014) Antonino Castellaneta et al.   HEPATOLOGY

Human adipose–derived mesenchymal stem cells attenuate liver ischemia–reperfusion injury and promote liver regeneration

(2014) Reza F. Saidi et al.   SURGERY

Eplerenone attenuated cardiac steatosis, apoptosis and diastolic dysfunction in experimental type-II diabetes

(2013) Elisa Ramírez et al.   Cardiovascular Diabetology

Current knowledge on oxidative stress in hepatic ischemia/reperfusion

(2013) M. Elias-Miró et al.   FREE RADICAL RESEARCH

Mitotracker probes and mitochondrial membrane potential

(2013) Han-Chen Lin et al.   SHOCK

AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

(2012) D. Grahame Hardie et al.   CHEMISTRY & BIOLOGY

Systemic administration of autologous adipose-derived mesenchymal stem cells alleviates hepatic ischemia–reperfusion injury in rats

(2012) Cheuk-Kwan Sun et al.   CRITICAL CARE MEDICINE

Roles of hepatocyte and myeloid CXC chemokine receptor-2 in liver recovery and regeneration after ischemia/reperfusion in mice

(2012) Heather L. Van Sweringen et al.   HEPATOLOGY

Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy

(2012) E. Itakura et al.   JOURNAL OF CELL SCIENCE

Bone marrow mesenchymal stem cells ameliorate hepatic ischemia/reperfusion injuries via inactivation of the MEK/ERK signaling pathway in rats

(2012) Guo-zheng Pan et al.   JOURNAL OF SURGICAL RESEARCH

Ischaemia–reperfusion injury in liver transplantation—from bench to bedside

(2012) Yuan Zhai et al.   Nature Reviews Gastroenterology & Hepatology

Current strategies to minimize hepatic ischemia–reperfusion injury by targeting reactive oxygen species

(2012) Hartmut Jaeschke et al.   Transplantation Reviews

FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model

(2011) Tobias G. Schips et al.   CARDIOVASCULAR RESEARCH

Targeting Mitochondria: A New Promising Approach for the Treatment of Liver Diseases

(2010) G. Serviddio et al.   CURRENT MEDICINAL CHEMISTRY

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

(2010) Jian-Xun Wang et al.   NATURE MEDICINE

Targeting Mitochondria

(2008) Adam T. Hoye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Novel Cardiac Apoptotic Pathway

(2008) Wei-Qi Tan et al.   CIRCULATION

Oxidative Inactivation of Key Mitochondrial Proteins Leads to Dysfunction and Injury in Hepatic Ischemia Reperfusion

(2008) Kwan–Hoon Moon et al.   GASTROENTEROLOGY

Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes

(2008) Jae-Sung Kim et al.   HEPATOLOGY