Identification of Compounds that Selectively Stabilize Specific G-Quadruplex Structures by Using a Thioflavin T-Displacement Assay as a Tool

Design and Synthesis of 2,2′-Diindolylmethanes to Selectively Target Certain G-Quadruplex DNA Structures

(2016) Madeleine Livendahl et al.   CHEMISTRY-A EUROPEAN JOURNAL

Antifibrotic and anticancer action of 5-ene amino/iminothiazolidinones

(2016) Danylo Kaminskyy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives

(2016) Jussara Amato et al.   JOURNAL OF MEDICINAL CHEMISTRY

Quadruplex Nucleic Acids as Novel Therapeutic Targets

(2016) Stephen Neidle   JOURNAL OF MEDICINAL CHEMISTRY

G-rich telomeric and ribosomal DNA sequences from the fission yeast genome form stable G-quadruplex DNA structuresin vitroand are unwound by the Pfh1 DNA helicase

(2016) Marcus Wallgren et al.   NUCLEIC ACIDS RESEARCH

Thioflavin T as an efficient fluorescence sensor for selective recognition of RNA G-quadruplexes

(2016) Shujuan Xu et al.   Scientific Reports

The Herpes Simplex Virus-1 genome contains multiple clusters of repeated G-quadruplex: Implications for the antiviral activity of a G-quadruplex ligand

(2015) Sara Artusi et al.   ANTIVIRAL RESEARCH

Development of fluorescent probes specific for parallel-stranded G-quadruplexes by a library approach

(2015) Liyun Zhang et al.   CHEMICAL COMMUNICATIONS

Looking for Efficient G-Quadruplex Ligands: Evidence for Selective Stabilizing Properties and Telomere Damage by Drug-Like Molecules

(2015) Bruno Pagano et al.   ChemMedChem

Short loop length and high thermal stability determine genomic instability induced by G-quadruplex-forming minisatellites

(2015) A. Piazza et al.   EMBO JOURNAL

An Ancient Yeast for Young Geneticists: A Primer on theSchizosaccharomyces pombeModel System

(2015) Charles S. Hoffman et al.   GENETICS

Ligand-Induced Conformational Changes with Cation Ejection upon Binding to Human Telomeric DNA G-Quadruplexes

(2015) Adrien Marchand et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of human copper trafficking by a small molecule significantly attenuates cancer cell proliferation

(2015) Jing Wang et al.   Nature Chemistry

Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription

(2015) Elena Tosoni et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes and their regulatory roles in biology

(2015) Daniela Rhodes et al.   NUCLEIC ACIDS RESEARCH

Pyridostatins selectively recognize two different forms of the human telomeric G-quadruplex structures and their anti-tumor activities in vitro

(2015) Li-Xia Wang et al.   TETRAHEDRON

An Ancient Yeast for Young Geneticists: A Primer on theSchizosaccharomyces pombeModel System

(2015) Charles S. Hoffman et al.   GENETICS

2-Guanidinoquinazolines as new inhibitors of the STAT3 pathway

(2014) Matthew G. LaPorte et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage

(2014) Nasim Sabouri et al.   BMC BIOLOGY

Selective recognition of parallel and anti-parallel thrombin-binding aptamer G-quadruplexes by different fluorescent dyes

(2014) Dan Zhao et al.   NUCLEIC ACIDS RESEARCH

G-quadruplex conformation and dynamics are determined by loop length and sequence

(2014) Ramreddy Tippana et al.   NUCLEIC ACIDS RESEARCH

Thioflavin T as a fluorescence light-up probe for G4 formation

(2014) Amandine Renaud de la Faverie et al.   NUCLEIC ACIDS RESEARCH

G-quadruplexes in viruses: function and potential therapeutic applications

(2014) Mathieu Métifiot et al.   NUCLEIC ACIDS RESEARCH

Multiple and Cooperative Binding of Fluorescence Light-up Probe Thioflavin T with Human Telomere DNA G-Quadruplex

(2013) Valérie Gabelica et al.   BIOCHEMISTRY

FDA-approved Drugs Selected Using Virtual Screening Bind Specifically to G-quadruplex DNA

(2013) Daimel Castillo-Gonzalez et al.   CURRENT PHARMACEUTICAL DESIGN

A Dynamic G-Quadruplex Region Regulates the HIV-1 Long Terminal Repeat Promoter

(2013) Rosalba Perrone et al.   JOURNAL OF MEDICINAL CHEMISTRY

Thioflavin T as an Efficient Inducer and Selective Fluorescent Sensor for the Human Telomeric G-Quadruplex DNA

(2012) Jyotirmayee Mohanty et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Identification of Novel Quadruplex Ligands from Small Molecule Libraries by FRET-Based High-Throughput Screening

(2011) Armin Benz et al.   CHEMBIOCHEM

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis

(2009) D. Drygin et al.   CANCER RESEARCH

The structures of quadruplex nucleic acids and their drug complexes

(2009) Stephen Neidle   CURRENT OPINION IN STRUCTURAL BIOLOGY

Structural polymorphism within a regulatory element of the human KRAS promoter: formation of G4-DNA recognized by nuclear proteins

(2008) Susanna Cogoi et al.   NUCLEIC ACIDS RESEARCH