The β-arrestin-biased β-adrenergic receptor blocker carvedilol enhances skeletal muscle contractility

Biased G Protein–Coupled Receptor Signaling

(2018) James W. Wisler et al.   CIRCULATION

β-arrestin 1 regulates β2-adrenergic receptor-mediated skeletal muscle hypertrophy and contractility

(2018) Jihee Kim et al.   Skeletal Muscle

Sarcopenia, cachexia, and muscle performance in heart failure: Review update 2016

(2017) Masakazu Saitoh et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Gαi is required for carvedilol-induced β1 adrenergic receptor β-arrestin biased signaling

(2017) Jialu Wang et al.   Nature Communications

Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling

(2017) Chun-Hua Liu et al.   Nature Communications

Effect of beta-adrenergic blockade with carvedilol on cachexia in severe chronic heart failure: results from the COPERNICUS trial

(2017) Andrew L. Clark et al.   Journal of Cachexia Sarcopenia and Muscle

GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling

(2016) Alex R.B. Thomsen et al.   CELL

β-arrestin–biased signaling through the β2-adrenergic receptor promotes cardiomyocyte contraction

(2016) Richard Carr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

β-Arrestin-Dependent Dopaminergic Regulation of Calcium Channel Activity in the Axon Initial Segment

(2016) Sungchil Yang et al.   Cell Reports

Espindolol for the treatment and prevention of cachexia in patients with stage III/IV non-small cell lung cancer or colorectal cancer: a randomized, double-blind, placebo-controlled, international multicentre phase II study (the ACT-ONE trial)

(2016) Andrew J. Stewart Coats et al.   Journal of Cachexia Sarcopenia and Muscle

Treating Sarcopenia in Older and Oldest Old

(2015) Anna Martone et al.   CURRENT PHARMACEUTICAL DESIGN

Muscle wasting in disease: molecular mechanisms and promising therapies

(2015) Shenhav Cohen et al.   NATURE REVIEWS DRUG DISCOVERY

Myostatin inhibition for treatment of sarcopenia

(2015) Gianni Parise et al.   Lancet Diabetes & Endocrinology

Adverse Health Consequences of Performance-Enhancing Drugs: An Endocrine Society Scientific Statement

(2014) Harrison G. Pope et al.   ENDOCRINE REVIEWS

Effects of Chronic Administration of Clenbuterol on Contractile Properties and Calcium Homeostasis in Rat Extensor Digitorum Longus Muscle

(2014) Pascal Sirvent et al.   PLoS One

Beta-Blockers in the Management of Hypertension and/or Chronic Kidney Disease

(2014) Hirofumi Tomiyama et al.   International Journal of Hypertension

Prevention of liver cancer cachexia-induced cardiac wasting and heart failure

(2013) Jochen Springer et al.   EUROPEAN HEART JOURNAL

Diagnostic criteria of cancer cachexia: relation to quality of life, exercise capacity and survival in unselected palliative care patients

(2013) Ola Wallengren et al.   SUPPORTIVE CARE IN CANCER

Rapid Determination of Myosin Heavy Chain Expression in Rat, Mouse, and Human Skeletal Muscle Using Multicolor Immunofluorescence Analysis

(2012) Darin Bloemberg et al.   PLoS One

Sarcopenia and Age-Related Endocrine Function

(2012) Kunihiro Sakuma et al.   International Journal of Endocrinology

Clenbuterol suppresses proteasomal and lysosomal proteolysis and atrophy-related genes in denervated rat soleus muscles independently of Akt

(2011) Dawit A. P. Gonçalves et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Arresting a Transient Receptor Potential (TRP) Channel

(2010) Arun K. Shukla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cachexia as a major underestimated and unmet medical need: facts and numbers

(2010) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Adult satellite cells and embryonic muscle progenitors have distinct genetic requirements

(2009) Christoph Lepper et al.   NATURE

Intramuscular β2-agonist administration enhances early regeneration and functional repair in rat skeletal muscle after myotoxic injury

(2008) James G. Ryall et al.   JOURNAL OF APPLIED PHYSIOLOGY

Clenbuterol Increases Lean Muscle Mass but Not Endurance in Patients With Chronic Heart Failure

(2008) Gayathri Kamalakkannan et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The potential and the pitfalls of β-adrenoceptor agonists for the management of skeletal muscle wasting

(2008) James G. Ryall et al.   PHARMACOLOGY & THERAPEUTICS

Role of β-Adrenoceptor Signaling in Skeletal Muscle: Implications for Muscle Wasting and Disease

(2008) Gordon S. Lynch et al.   PHYSIOLOGICAL REVIEWS

 -Blockers alprenolol and carvedilol stimulate  -arrestin-mediated EGFR transactivation

(2008) I.-M. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA