Structural and functional characterization of the bestrophin-2 anion channel

Molecular mechanisms of gating in the calcium-activated chloride channel bestrophin

(2019) Alexandria N Miller et al.   eLife

Routine determination of ice thickness for cryo-EM grids

(2018) William J. Rice et al.   JOURNAL OF STRUCTURAL BIOLOGY

SWISS-MODEL: homology modelling of protein structures and complexes

(2018) Andrew Waterhouse et al.   NUCLEIC ACIDS RESEARCH

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

New tools for the analysis and validation of cryo-EM maps and atomic models

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Guidelines for using Bsoft for high resolution reconstruction and validation of biomolecular structures from electron micrographs

(2017) J. Bernard Heymann   PROTEIN SCIENCE

Patient-specific mutations impair BESTROPHIN1’s essential role in mediating Ca2+-dependent Cl- currents in human RPE

(2017) Yao Li et al.   eLife

Modeling protein quaternary structure of homo- and hetero-oligomers beyond binary interactions by homology

(2017) Martino Bertoni et al.   Scientific Reports

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

The SWISS-MODEL Repository—new features and functionality

(2016) Stefan Bienert et al.   NUCLEIC ACIDS RESEARCH

Distinct regions that control ion selectivity and calcium-dependent activation in the bestrophin ion channel

(2016) George Vaisey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2

(2016) Dari Kimanius et al.   eLife

BEST1: the Best Target for Gene and Cell Therapies

(2015) Tingting Yang et al.   MOLECULAR THERAPY

EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy

(2015) Benjamin A Barad et al.   NATURE METHODS

Structure and insights into the function of a Ca2+-activated Cl− channel

(2014) Veronica Kane Dickson et al.   NATURE

Structure and selectivity in bestrophin ion channels

(2014) T. Yang et al.   SCIENCE

Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1

(2012) C.-Y. Cui et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CAVER 3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures

(2012) Eva Chovancova et al.   PLoS Computational Biology

Toward the estimation of the absolute quality of individual protein structure models

(2010) Pascal Benkert et al.   BIOINFORMATICS

Automated comparative protein structure modeling with SWISS-MODEL and Swiss-PdbViewer: A historical perspective

(2010) Nicolas Guex et al.   ELECTROPHORESIS

Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon

(2010) Kuai Yu et al.   JOURNAL OF CLINICAL INVESTIGATION

Bestrophins and retinopathies

(2010) Qinghuan Xiao et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Missense Mutations in a Retinal Pigment Epithelium Protein, Bestrophin-1, Cause Retinitis Pigmentosa

(2009) Alice E. Davidson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biallelic Mutation of BEST1 Causes a Distinct Retinopathy in Humans

(2008) Rosemary Burgess et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Bestrophin Cl− channels are highly permeable to HCO3−

(2008) Zhiqiang Qu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Molecular Physiology of Bestrophins: Multifunctional Membrane Proteins Linked to Best Disease and Other Retinopathies

(2008) H. Criss Hartzell et al.   PHYSIOLOGICAL REVIEWS