Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder

Pathogenesis of age-related HIV neurodegeneration

(2019) Miroslaw Mackiewicz et al.   JOURNAL OF NEUROVIROLOGY

Cerebrospinal fluid levels of glial marker YKL-40 strongly associated with axonal injury in HIV infection

(2019) Linn Hermansson et al.   Journal of Neuroinflammation

Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: Implications for therapeutic targeting of astroglia

(2019) Mary K. Swinton et al.   NEUROBIOLOGY OF DISEASE

Tenofovir disoproxil fumarate induces peripheral neuropathy and alters inflammation and mitochondrial biogenesis in the brains of mice

(2019) Jerel Adam Fields et al.   Scientific Reports

Cocaine evokes a profile of oxidative stress and impacts innate antiviral response pathways in astrocytes

(2018) Irma E. Cisneros et al.   NEUROPHARMACOLOGY

Astrocytic metabolic switch is a novel etiology for Cocaine and HIV-1 Tat-mediated neurotoxicity

(2018) Kalimuthusamy Natarajaseenivasan et al.   Cell Death & Disease

Alterations in brain TREM2 and Amyloid-β levels are associated with neurocognitive impairment in HIV-infected persons on antiretroviral therapy

(2018) Jerel Adam Fields et al.   JOURNAL OF NEUROCHEMISTRY

Macrophages but not Astrocytes Harbor HIV DNA in the Brains of HIV-1-Infected Aviremic Individuals on Suppressive Antiretroviral Therapy

(2018) Allen Ko et al.   Journal of Neuroimmune Pharmacology

HIV Neuroinfection and Alzheimer’s Disease: Similarities and Potential Links?

(2018) Geoffrey Canet et al.   Frontiers in Cellular Neuroscience

Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection

(2017) Brian P. Daniels et al.   JOURNAL OF CLINICAL INVESTIGATION

Combined Medication of Antiretroviral Drugs Tenofovir Disoproxil Fumarate, Emtricitabine, and Raltegravir Reduces Neural Progenitor Cell Proliferation In Vivo and In Vitro

(2017) Peipei Xu et al.   Journal of Neuroimmune Pharmacology

Accelerated and accentuated neurocognitive aging in HIV infection

(2017) David P. Sheppard et al.   JOURNAL OF NEUROVIROLOGY

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

Astrocytes as an HIV Reservoir: Mechanism of HIV Infection

(2016) Guan-Han Li et al.   CURRENT HIV RESEARCH

Energy metabolism and inflammation in brain aging and Alzheimer’s disease

(2016) Fei Yin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Mechanisms of HIV-1 Tat Neurotoxicity via CDK5 Translocation and Hyper-Activation: Role in HIV-Associated Neurocognitive Disorders

(2015) Jerel Fields et al.   CURRENT HIV RESEARCH

Gene Expression in HIV-Associated Neurocognitive Disorders

(2015) Umaporn Siangphoe et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

HIV-1 Tat Alters Neuronal Autophagy by Modulating Autophagosome Fusion to the Lysosome: Implications for HIV-Associated Neurocognitive Disorders

(2015) J. Fields et al.   JOURNAL OF NEUROSCIENCE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

C/EBPβ and C/EBPδ transcription factors: Basic biology and roles in the CNS

(2015) Marta Pulido-Salgado et al.   PROGRESS IN NEUROBIOLOGY

Astrocytic metabolic and inflammatory changes as a function of age

(2014) Tianyi Jiang et al.   AGING CELL

A common gene expression signature in Huntington’s disease patient brain regions

(2014) Andreas Neueder et al.   BMC Medical Genomics

CCAAT-Enhancer Binding Protein-β Expression and Elevation in Alzheimer’s Disease and Microglial Cell Cultures

(2014) Ron Strohmeyer et al.   PLoS One

A frontal cortex event-related potential driven by the basal forebrain

(2014) David P Nguyen et al.   eLife

voom: precision weights unlock linear model analysis tools for RNA-seq read counts

(2014) Charity W Law et al.   GENOME BIOLOGY

Systems analysis of human brain gene expression: mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer’s disease

(2013) Andrew J Levine et al.   BMC Medical Genomics

Transcriptome analysis of HIV-infected peripheral blood monocytes: Gene transcripts and networks associated with neurocognitive functioning

(2013) Andrew J. Levine et al.   JOURNAL OF NEUROIMMUNOLOGY

Detection of anti-tat antibodies in CSF of individuals with HIV-associated neurocognitive disorders

(2013) M. Bachani et al.   JOURNAL OF NEUROVIROLOGY

Age-dependent molecular alterations in the autophagy pathway in HIVE patients and in a gp120 tg mouse model: reversal with beclin-1 gene transfer

(2013) Jerel Fields et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorder

(2013) David B Clifford et al.   LANCET INFECTIOUS DISEASES

Transactivation of Atg4b by C/EBPβ Promotes Autophagy To Facilitate Adipogenesis

(2013) Liang Guo et al.   MOLECULAR AND CELLULAR BIOLOGY

HIV-1, Methamphetamine and Astrocyte Glutamate Regulation: Combined Excitotoxic Implications for Neuro-AIDS

(2012) Irma E. Cisneros et al.   CURRENT HIV RESEARCH

C/EBPβ regulates multiple IL-1β-induced human astrocyte inflammatory genes

(2012) Jerel Fields et al.   Journal of Neuroinflammation

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Identification of Epigenetically Altered Genes in Sporadic Amyotrophic Lateral Sclerosis

(2012) Claudia Figueroa-Romero et al.   PLoS One

Temporal orchestration of circadian autophagy rhythm by C/EBPβ

(2011) Di Ma et al.   EMBO JOURNAL

HIV encephalitis despite suppressed viraemia: a case of compartmentalized viral escape

(2011) R Bingham et al.   INTERNATIONAL JOURNAL OF STD & AIDS

IFN-  Mediates Enhancement of HIV Replication in Astrocytes by Inducing an Antagonist of the  -Catenin Pathway (DKK1) in a STAT 3-Dependent Manner

(2011) W. Li et al.   JOURNAL OF IMMUNOLOGY

CCAAT/enhancer binding protein β expression is increased in the brain during HIV-1-infection and contributes to regulation of astrocyte tissue inhibitor of metalloproteinase-1

(2011) Jerel Fields et al.   JOURNAL OF NEUROCHEMISTRY

Role of C/EBPβ Transcription Factor in Adult Hippocampal Neurogenesis

(2011) Marta Cortes-Canteli et al.   PLoS One

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments

(2010) Alexander Lachmann et al.   BIOINFORMATICS

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Conditional routing of information to the cortex: A model of the basal ganglia’s role in cognitive coordination.

(2010) Andrea Stocco et al.   PSYCHOLOGICAL REVIEW

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Extensive astrocyte infection is prominent in human immunodeficiency virus-associated dementia

(2009) Melissa J. Churchill et al.   ANNALS OF NEUROLOGY

CCAAT/enhancer-binding proteins and the pathogenesis of retrovirus infection

(2009) Yujie Liu et al.   Future Microbiology

Increased Accumulation of Intraneuronal Amyloid β in HIV-Infected Patients

(2009) Cristian L. Achim et al.   Journal of Neuroimmune Pharmacology

Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in  -Synuclein Models of Parkinson's and Lewy Body Diseases

(2009) B. Spencer et al.   JOURNAL OF NEUROSCIENCE

HIV-1 Tat Co-Operates with IFN-γ and TNF-α to Increase CXCL10 in Human Astrocytes

(2009) Rachel Williams et al.   PLoS One