NK cell-derived exosomes carry miR-207 and alleviate depression-like symptoms in mice

Exosomes from patients with major depression cause depressive-like behaviors in mice with involvement of miR-139-5p-regulated neurogenesis

(2020) Ze-Xu Wei et al.   NEUROPSYCHOPHARMACOLOGY

Plasma Exosomal miR-146b-5p and miR-222-3p are Potential Biomarkers for Lymph Node Metastasis in Papillary Thyroid Carcinomas

(2020) Ke Jiang et al.   OncoTargets and Therapy

Exosomal microRNA-144 from bone marrow-derived mesenchymal stem cells inhibits the progression of non-small cell lung cancer by targeting CCNE1 and CCNE2

(2020) Yuan Liang et al.   Stem Cell Research & Therapy

Bone marrow mesenchymal stem cells-derived exosomes improve injury of hippocampal neurons in rats with depression by upregulating microRNA-26a expression

(2020) Huirong Guo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Contribution of glia cells specifically astrocytes in the pathology of depression: immunohistochemical study in different brain areas

(2020) M. A. Eldomiaty et al.   FOLIA MORPHOLOGICA

Natural Killer Cells may Exert Antidepressant-like Effects in Mice by Controlling the Release of Inflammatory Factors

(2019) Lirong Hu et al.   NEUROSCIENCE

Exosome-encapsulated microRNAs as promising biomarkers for Alzheimer’s disease

(2019) Jian-jiao Chen et al.   REVIEWS IN THE NEUROSCIENCES

Exosome reporter mice reveal the involvement of exosomes in mediating neuron to astroglia communication in the CNS

(2019) Yuqin Men et al.   Nature Communications

A combined miRNA–piRNA signature to detect Alzheimer’s disease

(2019) Gaurav Jain et al.   Translational Psychiatry

Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons

(2018) Shan Huang et al.   FASEB JOURNAL

MicroRNAs and exosomes in depression: Potential diagnostic biomarkers

(2018) Jahanshir Tavakolizadeh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Depression and cardiovascular disease in elderly: Current understanding

(2018) Yaxin Zhang et al.   JOURNAL OF CLINICAL NEUROSCIENCE

TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons

(2018) Amrita Datta Chaudhuri et al.   Cell Death & Disease

Exosome Theranostics: Biology and Translational Medicine

(2018) Chuanjiang He et al.   Theranostics

Targeting and Therapy of Glioblastoma in a Mouse Model Using Exosomes Derived From Natural Killer Cells

(2018) Liya Zhu et al.   Frontiers in Immunology

Effect of Regulatory Network of Exosomes and microRNAs on Neurodegenerative Diseases

(2018) Xiao-Hua Zhu et al.   CHINESE MEDICAL JOURNAL

An astroglial basis of major depressive disorder? An overview

(2017) Qian Wang et al.   GLIA

Activation of P2X7 receptor and NLRP3 inflammasome assembly in hippocampal glial cells mediates chronic stress-induced depressive-like behaviors

(2017) Na Yue et al.   Journal of Neuroinflammation

Stimulation of IL-1β and IL-6 through NF-κB and sonic hedgehog-dependent pathways in mouse astrocytes by excretory/secretory products of fifth-stage larval Angiostrongylus cantonensis

(2017) Kuang-Yao Chen et al.   Parasites & Vectors

Exosomes as therapeutics: The implications of molecular composition and exosomal heterogeneity

(2016) Scott W. Ferguson et al.   JOURNAL OF CONTROLLED RELEASE

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

(2016) Veit Rothhammer et al.   NATURE MEDICINE

Density of GFAP-immunoreactive astrocytes is decreased in left hippocampi in major depressive disorder

(2016) J.A. Cobb et al.   NEUROSCIENCE

Exosomal microRNA miR-92a concentration in serum reflects human brown fat activity

(2016) Yong Chen et al.   Nature Communications

Uncoupling protein 2 modulation of the NLRP3 inflammasome in astrocytes and its implications in depression

(2016) Ren-Hong Du et al.   Redox Biology

Targeting astrocytes in major depression

(2015) Liang Peng et al.   Expert Review of Neurotherapeutics

The Effect of miR-132, miR-146a, and miR-155 on MRP8/TLR4-Induced Astrocyte-Related Inflammation

(2015) Huimin Kong et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Icariin exerts an antidepressant effect in an unpredictable chronic mild stress model of depression in rats and is associated with the regulation of hippocampal neuroinflammation

(2015) B. Liu et al.   NEUROSCIENCE

Targeting astrocytes in major depression

(2015) Liang Peng et al.   Expert Review of Neurotherapeutics

A review of the relationship between proinflammatory cytokines and major depressive disorder

(2014) Juan Joseph Young et al.   JOURNAL OF AFFECTIVE DISORDERS

Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

(2014) Claudia Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

TRIL Is Involved in Cytokine Production in the Brain followingEscherichia coliInfection

(2014) Paulina Wochal et al.   JOURNAL OF IMMUNOLOGY

The Epidemiology of Depression Across Cultures

(2013) Ronald C. Kessler et al.   Annual Review of Public Health

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010

(2013) Harvey A Whiteford et al.   LANCET

Chronic mild stress-induced changes of risk assessment behaviors in mice are prevented by chronic treatment with fluoxetine but not diazepam

(2013) Che Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effect of diclofenac and antidepressants on the inflammatory response in astrocyte cell culture

(2013) Md. Mamun Al-Amin et al.   INFLAMMOPHARMACOLOGY

Exosomes and immune surveillance of neoplastic lesions: a review

(2012) H-G Zhang et al.   BIOTECHNIC & HISTOCHEMISTRY

The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses

(2012) Masaaki Iwata et al.   BRAIN BEHAVIOR AND IMMUNITY

Glial Loss in the Prefrontal Cortex Is Sufficient to Induce Depressive-like Behaviors

(2008) Mounira Banasr et al.   BIOLOGICAL PSYCHIATRY

The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression

(2008) Michael Maes et al.   METABOLIC BRAIN DISEASE