A direct access to isoxazoles from ynones using trimethylsilyl azide as amino surrogate under metal/catalyst free conditions

Recent Developments in the Synthesis and Reactivity of Isoxazoles: Metal Catalysis and Beyond

(2015) Feng Hu et al.   ADVANCED SYNTHESIS & CATALYSIS

Palladium-Catalyzed Regio- and Stereoselective Cross-Addition of Terminal Alkynes to Ynol Ethers and Synthesis of 1,4-Enyn-3-ones

(2015) Madala Hari Babu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Trifluoromethylazidation of Alkynes: Efficient Access to CF3-Substituted Azirines and Aziridines

(2015) Fei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Substitution dependent stereoselectivity switch in palladium catalyzed hydroalkynylation of ynamides: a regio and stereoselective synthesis of ynenamides

(2015) Vikas Dwivedi et al.   CHEMICAL COMMUNICATIONS

Regioselectivity in the Au-catalyzed hydration and hydroalkoxylation of alkynes

(2015) Justin A. Goodwin et al.   CHEMICAL COMMUNICATIONS

Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity

(2015) Ruth Dorel et al.   CHEMICAL REVIEWS

Silver-catalysed reactions of alkynes: recent advances

(2015) Guichun Fang et al.   CHEMICAL SOCIETY REVIEWS

Pd-Catalyzed Isocyanide Assisted Reductive Cyclization of 1-(2-Hydroxyphenyl)-propargyl Alcohols for 2-Alkyl/Benzyl Benzofurans and Their Useful Oxidative Derivatization

(2015) Manda Rajesh et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 3-Sulfonylamino Quinolines from 1-(2-Aminophenyl) Propargyl Alcohols through a Ag(I)-Catalyzed Hydroamination, (2 + 3) Cycloaddition, and an Unusual Strain-Driven Ring Expansion

(2015) Yalla Kiran Kumar et al.   ORGANIC LETTERS

Selective 5-exo-digCyclization ofin SituSynthesizedN-Boc-2-aminophenyl Ethoxyethynyl Carbenols: Synthesis of Multifunctional Indoles and Their Derivatives

(2014) Nuligonda Thirupathi et al.   ADVANCED SYNTHESIS & CATALYSIS

Silver(I)-Catalyzed Hydroazidation of Ethynyl Carbinols: Synthesis of 2-Azidoallyl Alcohols

(2014) Zhenhua Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Synthesis of 4-Fluoroisoxazoles through Gold-Catalyzed Cascade Cyclization–Fluorination of 2-Alkynone O-Methyl Oximes

(2014) Yunkyung Jeong et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent Advances in the Synthesis of Thiophene Derivatives by Cyclization of Functionalized Alkynes

(2014) Raffaella Mancuso et al.   MOLECULES

DMAP Promoted Tandem Addition Reactions Forming Substituted Tetrahydroxanthones

(2014) Emmanuel B. Castillo-Contreras et al.   ORGANIC LETTERS

Iodo Meyer–Schuster Rearrangement of 3-Alkoxy-2-yn-1-ols for β-Mono (Exclusively Z-Selective)-/Disubstituted α-Iodo-α,β-Unsaturated Esters

(2014) Surendra Puri et al.   ORGANIC LETTERS

Tandem Synthesis of 3-Halo-5-Substituted Isoxazoles from 1-Copper(I) Alkynes and Dihaloformaldoximes

(2014) Wenwen Chen et al.   ORGANIC LETTERS

Oxime-Mediated Facile Access to 5-Methylisoxazoles and Applications in the Synthesis of Valdecoxib and Oxacillin

(2014) Kui-Yong Dong et al.   ORGANIC LETTERS

Palladium-Catalyzed Tandem Intramolecular Oxy/Amino-Palladation/Isocyanide Insertion: Synthesis of α-Benzofuranyl/Indolylacetamides

(2014) Nuligonda Thirupathi et al.   ORGANIC LETTERS

Recent Advances on the Lewis Acid-Catalyzed Cascade Rearrangements of Propargylic Alcohols and Their Derivatives

(2014) Yuanxun Zhu et al.   ACS Catalysis

Cyclometallated Gold(III) Complexes as Effective Catalysts for Synthesis of Propargylic Amines, Chiral Allenes and Isoxazoles

(2013) Karen Ka-Yan Kung et al.   ADVANCED SYNTHESIS & CATALYSIS

Chemicals from Alkynes with Palladium Catalysts

(2013) Rafael Chinchilla et al.   CHEMICAL REVIEWS

Synthesis and Biological Evaluation of Aryloxazole Derivatives as Antimitotic and Vascular-Disrupting Agents for Cancer Therapy

(2013) Min Jeong Choi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Pharmacological Characterization of N- and O-Substituted 5,6,7,8-Tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol Analogues: Novel 5-HT2A/5-HT2C Receptor Agonists with Pro-Cognitive Properties

(2013) Anders A. Jensen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Substituted 3-Iodocoumarins and 3-Iodobutenolides via Electrophilic Iodocyclization of Ethoxyalkyne Diols

(2013) Maddi Sridhar Reddy et al.   JOURNAL OF ORGANIC CHEMISTRY

Gold-Mediated Synthesis and Functionalization of Chiral Halopyridones

(2013) Khanh Hung Nguyen et al.   JOURNAL OF ORGANIC CHEMISTRY

Cu-Catalyzed Conversion of Propargyl Acetates to E-α,β-Unsaturated Amides via Ketenimine Formation with Sulfonyl Azides

(2013) Yalla Kiran Kumar et al.   JOURNAL OF ORGANIC CHEMISTRY

Drug-Induced Conformational and Dynamical Changes of the S31N Mutant of the Influenza M2 Proton Channel Investigated by Solid-State NMR

(2013) Jonathan K. Williams et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Spirobacillene A

(2013) William P. Unsworth et al.   ORGANIC LETTERS

Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus

(2013) Jun Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Asymmetric Synthesis of Dihydropyranones from Ynones by Sequential Copper(I)-Catalyzed Direct Aldol and Silver(I)-Catalyzed Oxy-Michael Reactions

(2012) Shi-Liang Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Heterocycles via Palladium-Catalyzed Carbonylations

(2012) Xiao-Feng Wu et al.   CHEMICAL REVIEWS

Copper-Catalyzed Synthesis of Trisubstituted Isoxazoles via a Cascade Cyclization–Migration Process

(2012) Masafumi Ueda et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Trisubstituted Isoxazoles by Palladium(II)-Catalyzed Cascade Cyclization–Alkenylation of 2-Alkyn-1-one O-Methyl Oximes

(2012) Zhigang She et al.   JOURNAL OF ORGANIC CHEMISTRY

A New Synthesis of γ-Butyrolactones via AuCl3- or Hg(II)-Catalyzed Intramolecular Hydroalkoxylation of 4-Bromo-3-yn-1-ols

(2012) Maddi Sridhar Reddy et al.   ORGANIC LETTERS

Catalytic enantioselective carbon-carbon bond formation using cycloisomerization reactions

(2012) Iain D. G. Watson et al.   Chemical Science

When gold can do what iodine cannot do: A critical comparison

(2011) Sara Hummel et al.   Beilstein Journal of Organic Chemistry

Recent advances in the gold-catalyzed additions to C–C multiple bonds

(2011) He Huang et al.   Beilstein Journal of Organic Chemistry

Transition Metal Catalyzed Cycloisomerizations of 1,n-Allenynes and -Allenenes

(2011) Corinne Aubert et al.   CHEMICAL REVIEWS

Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom

(2011) Benhur Godoi et al.   CHEMICAL REVIEWS

Zinc Triflate Catalyzed Aerobic Cross-Dehydrogenative Coupling (CDC) of Alkynes with Nitrones: A New Entry to Isoxazoles

(2011) Sandip Murarka et al.   ORGANIC LETTERS

Silver-catalyzed synthesis of disubstituted isoxazoles by cyclization of alkynyl oxime ethers

(2011) Masafumi Ueda et al.   TETRAHEDRON

Direct Synthesis of Trisubstituted Isoxazoles through Gold-Catalyzed Domino Reaction of Alkynyl Oxime Ethers

(2010) Masafumi Ueda et al.   ORGANIC LETTERS

3,4-Diaryl-isoxazoles and -imidazoles as Potent Dual Inhibitors of p38α Mitogen Activated Protein Kinase and Casein Kinase 1δ†

(2009) Christian Peifer et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Substituted Pyrrolin-4-ones from Amino Acids in Mild Conditions via a Gold-Catalyzed Approach

(2009) Nicolas Gouault et al.   JOURNAL OF ORGANIC CHEMISTRY

Facile One-Pot Synthesis of 4,5-Disubstituted 1,2,3-(NH)-Triazoles through Sonogashira Coupling/1,3-Dipolar Cycloaddition of Acid Chlorides, Terminal Acetylenes, and Sodium Azide

(2009) Jihui Li et al.   ORGANIC LETTERS

Synthesis of a quinolone library from ynones

(2009) Timothy R. Ward et al.   TETRAHEDRON LETTERS

Cycloisomerization of 1,n-Enynes: Challenging Metal-Catalyzed Rearrangements and Mechanistic Insights

(2008) Véronique Michelet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

5-tert-Butyl-N-pyrazol-4-yl-4,5,6,7-tetrahydrobenzo[d]isoxazole-3-carboxamide Derivatives as Novel Potent Inhibitors ofMycobacterium tuberculosisPantothenate Synthetase: Initiating a Quest for New Antitubercular Drugs

(2008) Subash Velaparthi et al.   JOURNAL OF MEDICINAL CHEMISTRY