Frontline Science: LPS‐inducible SLC30A1 drives human macrophage‐mediated zinc toxicity against intracellular Escherichia coli

Zinc toxicity and iron-sulfur cluster biogenesis in Escherichia coli

(2019) Jianghui Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Zinc transporter 1 (ZNT1) expression on the cell surface is elaborately controlled by cellular zinc levels

(2019) Yukina Nishito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

For when bacterial infections persist: Toll-like receptor-inducible direct antimicrobial pathways in macrophages

(2018) Claudia J. Stocks et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Nitric Oxide Disrupts Zinc Homeostasis in Salmonella enterica Serovar Typhimurium

(2018) Elaine R. Frawley et al.   mBio

Localization of all four ZnT zinc transporters in Dictyostelium and impact of ZntA and ZntB knockout on bacteria killing

(2018) Caroline Barisch et al.   JOURNAL OF CELL SCIENCE

Zinc-dependent substrate-level phosphorylation powers Salmonella growth under nitrosative stress of the innate host response

(2018) Liam Fitzsimmons et al.   PLoS Pathogens

SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages

(2017) Lin Luo et al.   Nature Communications

Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBPβ Inhibition

(2017) Charlie J. Pyle et al.   PLoS One

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages

(2016) Ronan Kapetanovic et al.   FASEB JOURNAL

IL-4 Induces Metallothionein 3- and SLC30A4-Dependent Increase in Intracellular Zn 2+ that Promotes Pathogen Persistence in Macrophages

(2016) Kavitha Subramanian Vignesh et al.   Cell Reports

Heterodimerization, Altered Subcellular Localization, and Function of Multiple Zinc Transporters in Viable Cells Using Bimolecular Fluorescence Complementation

(2015) Yarden Golan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kidney organoids from human iPS cells contain multiple lineages and model human nephrogenesis

(2015) Minoru Takasato et al.   NATURE

In SituDimerization of Multiple Wild Type and Mutant Zinc Transporters in Live Cells Using Bimolecular Fluorescence Complementation

(2014) Inbal Lasry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ZnT-1 extrudes zinc from mammalian cells functioning as a Zn2+/H+ exchanger

(2014) Eden Shusterman et al.   Metallomics

Extracellular Zinc Competitively Inhibits Manganese Uptake and Compromises Oxidative Stress Management in Streptococcus pneumoniae

(2014) Bart A. Eijkelkamp et al.   PLoS One

Transition metal ions at the crossroads of mucosal immunity and microbial pathogenesis

(2014) Vladimir E. Diaz-Ochoa et al.   Frontiers in Cellular and Infection Microbiology

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper

(2013) Sian L. Stafford et al.   BIOSCIENCE REPORTS

Granulocyte Macrophage-Colony Stimulating Factor Induced Zn Sequestration Enhances Macrophage Superoxide and Limits Intracellular Pathogen Survival

(2013) Kavitha Subramanian Vignesh et al.   IMMUNITY

The Pseudokinase MLKL Mediates Necroptosis via a Molecular Switch Mechanism

(2013) James M. Murphy et al.   IMMUNITY

The SLC30 family of zinc transporters – A review of current understanding of their biological and pathophysiological roles

(2013) Liping Huang et al.   MOLECULAR ASPECTS OF MEDICINE

The 4-cysteine zinc-finger motif of the RNA polymerase regulator DksA serves as a thiol switch for sensing oxidative and nitrosative stress

(2013) Calvin A. Henard et al.   MOLECULAR MICROBIOLOGY

TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1

(2013) D M Moujalled et al.   Cell Death & Disease

ZIP8 Regulates Host Defense through Zinc-Mediated Inhibition of NF-κB

(2013) Ming-Jie Liu et al.   Cell Reports

Silver(I), Mercury(II), Cadmium(II), and Zinc(II) Target Exposed Enzymic Iron-Sulfur Clusters when They Toxify Escherichia coli

(2012) Fang Fang Xu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Nutritional immunity: transition metals at the pathogen–host interface

(2012) M. Indriati Hood et al.   NATURE REVIEWS MICROBIOLOGY

Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages

(2011) Hélène Botella et al.   Cell Host & Microbe

Nutrient Metal Sequestration by Calprotectin Inhibits Bacterial Superoxide Defense, Enhancing Neutrophil Killing of Staphylococcus aureus

(2011) Thomas E. Kehl-Fie et al.   Cell Host & Microbe

Intramacrophage survival of uropathogenic Escherichia coli: Differences between diverse clinical isolates and between mouse and human macrophages

(2011) Nilesh J. Bokil et al.   IMMUNOBIOLOGY

A Molecular Mechanism for Bacterial Susceptibility to Zinc

(2011) Christopher A. McDevitt et al.   PLoS Pathogens

Silencing of ZnT1 reduces Zn2+ efflux in cultured cortical neurons

(2008) Yan Qin et al.   NEUROSCIENCE LETTERS