Gut Microbiota Contributes to Spontaneous Colitis in E3 Ligase Itch-Deficient Mice

The Intestinal Microbiota in Colorectal Cancer

(2018) Herbert Tilg et al.   CANCER CELL

IL-17-driven intestinal fibrosis is inhibited by Itch-mediated ubiquitination of HIC-5

(2017) J Paul et al.   Mucosal Immunology

An insider's perspective: Bacteroides as a window into the microbiome

(2017) Aaron G. Wexler et al.   Nature Microbiology

Itch inhibits IL-17-mediated colon inflammation and tumorigenesis by ROR-γt ubiquitination

(2016) Mahesh Kathania et al.   NATURE IMMUNOLOGY

Multifaceted role of the ubiquitin ligase Itch in immune regulation

(2015) K Venuprasad et al.   IMMUNOLOGY AND CELL BIOLOGY

The Fire Within: Microbes Inflame Tumors

(2014) Nicola Gagliani et al.   CELL

The Treatment-Naive Microbiome in New-Onset Crohn’s Disease

(2014) Dirk Gevers et al.   Cell Host & Microbe

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

(2013) Dan Knights et al.   GUT

Intestinal Microbiota Containing Barnesiella Species Cures Vancomycin-Resistant Enterococcus faecium Colonization

(2013) Carles Ubeda et al.   INFECTION AND IMMUNITY

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer

(2013) Aurélie Couturier-Maillard et al.   JOURNAL OF CLINICAL INVESTIGATION

Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer

(2013) B. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The NOD-Like Receptor NLRP12 Attenuates Colon Inflammation and Tumorigenesis

(2011) Md. Hasan Zaki et al.   CANCER CELL

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Commensal Bacteroides Species Induce Colitis in Host-Genotype-Specific Fashion in a Mouse Model of Inflammatory Bowel Disease

(2011) Seth M. Bloom et al.   Cell Host & Microbe

Human nutrition, the gut microbiome and the immune system

(2011) Andrew L. Kau et al.   NATURE

Human ITCH E3 Ubiquitin Ligase Deficiency Causes Syndromic Multisystem Autoimmune Disease

(2010) Naomi J. Lohr et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Homeostasis and Inflammation in the Intestine

(2010) Wendy S. Garrett et al.   CELL

The struggle within: Microbial influences on colorectal cancer

(2010) Janelle C. Arthur et al.   INFLAMMATORY BOWEL DISEASES

Global patterns of 16S rRNA diversity at a depth of millions of sequences per sample

(2010) J. G. Caporaso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The joint–gut axis in inflammatory bowel diseases

(2009) Lianne K.P.M. Brakenhoff et al.   Journal of Crohns & Colitis

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

(2009) Shaoguang Wu et al.   NATURE MEDICINE

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evolution of Mammals and Their Gut Microbes

(2008) R. E. Ley et al.   SCIENCE