Somatic SMAD3-activating mutations cause melorheostosis by up-regulating the TGF-β/SMAD pathway

Melorheostotic Bone Lesions Caused by Somatic Mutations in MAP2K1 Have Deteriorated Microarchitecture and Periosteal Reaction

(2019) Nadja Fratzl-Zelman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

A mutation update on the LDS-associated genes TGFB2/3 and SMAD2/3

(2018) Dorien Schepers et al.   HUMAN MUTATION

Contextual determinants of TGFβ action in development, immunity and cancer

(2018) Charles J. David et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Somatic activating mutations in MAP2K1 cause melorheostosis

(2018) Heeseog Kang et al.   Nature Communications

Distinct Clinical and Pathological Features of Melorheostosis Associated With Somatic MAP2K1 Mutations

(2018) Smita Jha et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Structural basis for receptor-regulated SMAD recognition by MAN1

(2018) Ken-ichi Miyazono et al.   NUCLEIC ACIDS RESEARCH

TGF-β Signaling Regulates Cementum Formation through Osterix Expression

(2016) Hwajung Choi et al.   Scientific Reports

Defective Connective Tissue Remodeling in Smad3 Mice Leads to Accelerated Aneurysmal Growth Through Disturbed Downstream TGF-β Signaling

(2016) I. van der Pluijm et al.   EBioMedicine

Periosteum: Characteristic imaging findings with emphasis on radiologic-pathologic comparisons

(2014) Damien Bisseret et al.   SKELETAL RADIOLOGY

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Inhibition of TGF-  Signaling at the Nuclear Envelope: Characterization of Interactions Between MAN1, Smad2 and Smad3, and PPM1A

(2013) B. Bourgeois et al.   Science Signaling

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

SMAD2, SMAD3 and SMAD4 Mutations in Colorectal Cancer

(2012) N. I. Fleming et al.   CANCER RESEARCH

Signaling Networks that Control the Lineage Commitment and Differentiation of Bone Cells

(2012) Carrie S. Soltanoff et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Transforming Growth Factor β Signaling Perturbation in the Loeys-Dietz Syndrome

(2012) A. Pezzini et al.   CURRENT MEDICINAL CHEMISTRY

TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation

(2012) Guiqian Chen et al.   International Journal of Biological Sciences

Transforming Growth Factor   Inhibits Bone Morphogenetic Protein-Induced Transcription through Novel Phosphorylated Smad1/5-Smad3 Complexes

(2012) E. Gronroos et al.   MOLECULAR AND CELLULAR BIOLOGY

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Interferon-γ plays a role in bone formation in vivo and rescues osteoporosis in ovariectomized mice

(2011) Gustavo Duque et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mutations in SMAD3 cause a syndromic form of aortic aneurysms and dissections with early-onset osteoarthritis

(2011) Ingrid M B H van de Laar et al.   NATURE GENETICS

Noncanonical TGF  Signaling Contributes to Aortic Aneurysm Progression in Marfan Syndrome Mice

(2011) T. M. Holm et al.   SCIENCE

Smad2 and 3 transcription factors control muscle mass in adulthood

(2009) Roberta Sartori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Essential Role of TGF-β Signaling in Glucose-Induced Cell Hypertrophy

(2009) Liyu Wu et al.   DEVELOPMENTAL CELL

Distinct Roles for Mammalian Target of Rapamycin Complexes in the Fibroblast Response to Transforming Growth Factor- 

(2008) R. A. Rahimi et al.   CANCER RESEARCH

TGF-β has paradoxical and context dependent effects on proliferation and anoikis in human colorectal cancer cell lines

(2008) Nina M. Muñoz et al.   GROWTH FACTORS

A Cross-Talk Between Stromal Cell-Derived Factor-1 and Transforming Growth Factor-β Controls the Quiescence/Cycling Switch of CD34+Progenitors Through FoxO3 and Mammalian Target of Rapamycin

(2008) Aurélie Chabanon et al.   STEM CELLS

Bone mineralization density distribution in health and disease

(2007) P. Roschger et al.   BONE