Multi-component self-assembled anti-tumor nano-vaccines based on MUC1 glycopeptides

Peptide-based synthetic vaccines

(2016) Mariusz Skwarczynski et al.   Chemical Science

Glycopeptide Nanoconjugates Based on Multilayer Self-Assembly as an Antitumor Vaccine

(2015) Yan-Fang Liu et al.   BIOCONJUGATE CHEMISTRY

Linear synthesis and immunological properties of a fully synthetic vaccine candidate containing a sialylated MUC1 glycopeptide

(2015) Pamela Thompson et al.   CHEMICAL COMMUNICATIONS

Recent advances in the molecular design of synthetic vaccines

(2015) Lyn H. Jones   Nature Chemistry

Synthetic Multivalent Glycopeptide-Lipopeptide Antitumor Vaccines: Impact of the Cluster Effect on the Killing of Tumor Cells

(2014) Hui Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Fully Synthetic Four-Component Antitumor Vaccine Consisting of a Mucin Glycopeptide Antigen Combined with Three Different T-Helper-Cell Epitopes

(2014) Björn Palitzsch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Immune and Anticancer Responses Elicited by Fully Synthetic Aberrantly Glycosylated MUC1 Tripartite Vaccines Modified by a TLR2 or TLR9 Agonist

(2014) Abu-Baker M. Abdel-Aal et al.   CHEMBIOCHEM

Covalent Bond or Noncovalent Bond: A Supramolecular Strategy for the Construction of Chemically Synthesized Vaccines

(2014) Yue Gao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cutting Edge: New Chimeric NOD2/TLR2 Adjuvant Drastically Increases Vaccine Immunogenicity

(2014) Vincent Pavot et al.   JOURNAL OF IMMUNOLOGY

CpG-Loaded Multifunctional Cationic Nanohydrogel Particles as Self-Adjuvanting Glycopeptide Antitumor Vaccines

(2014) Sebastian Hartmann et al.   Advanced Healthcare Materials

Covalently Coupled Immunostimulant Heterodimers

(2013) Rock J. Mancini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Adjuvanting Synthetic Antitumor Vaccines from MUC1 Glycopeptides Conjugated to T-Cell Epitopes from Tetanus Toxoid

(2013) Hui Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Variation of the Glycosylation Pattern in MUC1 Glycopeptide BSA Vaccines and Its Influence on the Immune Response

(2012) Hui Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fully Synthetic Self-Adjuvanting Thioether-Conjugated GlycopeptideLipopeptide Antitumor Vaccines for the Induction of Complement-Dependent Cytotoxicity against Tumor Cells

(2012) Hui Cai et al.   CHEMISTRY-A EUROPEAN JOURNAL

IL-6 Triggers IL-21 production by human CD4+ T cells to drive STAT3-dependent plasma cell differentiation in B cells

(2012) Sean A Diehl et al.   IMMUNOLOGY AND CELL BIOLOGY

a Totally Synthetic, Self-Assembling, Adjuvant-Free MUC1 Glycopeptide Vaccine for Cancer Therapy

(2012) Zhi-Hua Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Adjuvanting Multicomponent Cancer Vaccine Candidates Combining Per-Glycosylated MUC1 Glycopeptides and the Toll-like Receptor 2 Agonist Pam3CysSer

(2011) Brendan L. Wilkinson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of a MUC1-glycopeptide–BSA conjugate vaccine bearing the 3′-deoxy-3′-fluoro-Thomsen–Friedenreich antigen

(2011) Anja Hoffmann-Röder et al.   CHEMICAL COMMUNICATIONS

Towards a Fully Synthetic MUC1-Based Anticancer Vaccine: Efficient Conjugation of Glycopeptides with Mono-, Di-, and Tetravalent Lipopeptides Using Click Chemistry

(2011) Hui Cai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine

(2011) V. Lakshminarayanan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthetic Antitumor Vaccines from Tetanus Toxoid Conjugates of MUC1 Glycopeptides with the Thomsen-Friedenreich Antigen and a Fluorine-Substituted Analogue

(2010) Anja Hoffmann-Röder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of MUC1–lipopeptide chimeras

(2010) Brendan L. Wilkinson et al.   CHEMICAL COMMUNICATIONS

Perfluoroalkylated amphiphilic MUC1 glycopeptideantigens as tools for cancer immunotherapy

(2010) Anja Hoffmann-Röder et al.   CHEMICAL COMMUNICATIONS

Immunotherapy for cancer: synthetic carbohydrate-based vaccines

(2009) Therese Buskas et al.   CHEMICAL COMMUNICATIONS

Sequential Polarization and Imprinting of Type 1 T Helper Lymphocytes by Interferon-γ and Interleukin-12

(2009) Edda G. Schulz et al.   IMMUNITY