The role of spreading depolarizations and electrographic seizures in early injury progression of the rat photothrombosis stroke model

Seizure-induced microvascular injury is associated with impaired neurovascular coupling and blood-brain barrier dysfunction

(2019) Ofer Prager et al.   EPILEPSIA

Na+/K+-ATPase α isoform deficiency results in distinct spreading depolarization phenotypes

(2019) Clemens Reiffurth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Early blood-brain barrier dysfunction predicts neurological outcome following aneurysmal subarachnoid hemorrhage

(2019) Svetlana Lublinsky et al.   EBioMedicine

Spreading depolarizations trigger caveolin-1-dependent endothelial transcytosis

(2018) Homa Sadeghian et al.   ANNALS OF NEUROLOGY

Terminal spreading depolarization and electrical silence in death of human cerebral cortex

(2018) Jens P. Dreier et al.   ANNALS OF NEUROLOGY

The negative ultraslow potential, electrophysiological correlate of infarction in the human cortex

(2018) Janos Lückl et al.   BRAIN

Pharmacotherapy for Refractory and Super-Refractory Status Epilepticus in Adults

(2018) Martin Holtkamp   DRUGS

Ketamine reduces deleterious consequences of spreading depolarizations

(2018) Katelyn M. Reinhart et al.   EXPERIMENTAL NEUROLOGY

Systematic review of the pharmacological agents that have been tested against spreading depolarizations

(2018) Anna Klass et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Spreading depolarization in acute brain injury inhibited by ketamine: a prospective, randomized, multiple crossover trial

(2018) Andrew P. Carlson et al.   JOURNAL OF NEUROSURGERY

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Spreading depolarization is not an epiphenomenon but the principal mechanism of the cytotoxic edema in various gray matter structures of the brain during stroke

(2018) Jens P. Dreier et al.   NEUROPHARMACOLOGY

Sedation of Patients with Acute Aneurysmal Subarachnoid Hemorrhage with Ketamine Is Safe and Might Influence the Occurrence of Cerebral Infarctions Associated with Delayed Cerebral Ischemia

(2017) Christian Von der brelie et al.   World Neurosurgery

Altered hypermetabolic response to cortical spreading depolarizations after traumatic brain injury in rats

(2016) Baptiste Balança et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Epileptiform activity and spreading depolarization in the blood–brain barrier-disrupted peri-infarct hippocampus are associated with impaired GABAergic inhibition and synaptic plasticity

(2016) Kristina Lippmann et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Ketamine modulation of the haemodynamic response to spreading depolarization in the gyrencephalic swine brain

(2016) Renán Sánchez-Porras et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A role of the sodium pump in spreading ischemia in rats

(2016) Sebastian Major et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group

(2016) Jens P Dreier et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão’s legacy

(2016) Jed A Hartings et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Complications in Aneurysmal Subarachnoid Hemorrhage Patients With and Without Subdural Electrode Strip for Electrocorticography

(2016) Christoph Drenckhahn et al.   JOURNAL OF CLINICAL NEUROPHYSIOLOGY

The prognosis of acute symptomatic seizures after ischaemic stroke

(2016) Thomas Leung et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Anesthesia in Experimental Stroke Research

(2016) Ulrike Hoffmann et al.   Translational Stroke Research

Spreading depolarizations mediate excitotoxicity in the development of acute cortical lesions

(2015) Jason M. Hinzman et al.   EXPERIMENTAL NEUROLOGY

Ultrastructural analysis of blood–brain barrier breakdown in the peri-infarct zone in young adult and aged mice

(2015) Patrick C Nahirney et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Supply-Demand Mismatch Transients in Susceptible Peri-infarct Hot Zones Explain the Origins of Spreading Injury Depolarizations

(2015) Daniel von Bornstädt et al.   NEURON

The Stroke-Migraine Depolarization Continuum

(2015) Jens P. Dreier et al.   NEURON

Monitoring Stroke Progression: In Vivo Imaging of Cortical Perfusion, Blood—Brain Barrier Permeability and Cellular Damage in the Rat Photothrombosis Model

(2014) Karl Schoknecht et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blood—Brain Barrier Breakdown Involves Four Distinct Stages of Vascular Damage in Various Models of Experimental Focal Cerebral Ischemia

(2014) Martin Krueger et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dynamic perfusion and diffusion MRI of cortical spreading depolarization in photothrombotic ischemia

(2014) Yu-Chieh Jill Kao et al.   NEUROBIOLOGY OF DISEASE

Clusters of Cortical Spreading Depolarizations in a Patient with Intracerebral Hemorrhage: A Multimodal Neuromonitoring Study

(2014) A. J. Schiefecker et al.   Neurocritical Care

Continuous EEG Monitoring in Aneurysmal Subarachnoid Hemorrhage: A Systematic Review

(2014) Daniel Kondziella et al.   Neurocritical Care

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

The effect of ketamine on optical and electrical characteristics of spreading depolarizations in gyrencephalic swine cortex

(2014) Renán Sánchez-Porras et al.   NEUROPHARMACOLOGY

Nonconvulsive seizures after subarachnoid hemorrhage: Multimodal detection and outcomes

(2013) Jan Claassen et al.   ANNALS OF NEUROLOGY

Treatment of Status Epilepticus with Ketamine, Are we There yet?

(2013) Frederic Dorandeu et al.   CNS Neuroscience & Therapeutics

Ketamine use in the treatment of refractory status epilepticus

(2013) Andrea S. Synowiec et al.   EPILEPSY RESEARCH

Isoflurane suppresses cortical spreading depolarizations compared to propofol — Implications for sedation of neurocritical care patients

(2013) Masatoshi Takagaki et al.   EXPERIMENTAL NEUROLOGY

Blood–brain barrier opening to large molecules does not imply blood–brain barrier opening to small ions

(2013) E.J. Kang et al.   NEUROBIOLOGY OF DISEASE

Effect of analgesics and sedatives on the occurrence of spreading depolarizations accompanying acute brain injury

(2012) D. N. Hertle et al.   BRAIN

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Christopher J L Murray et al.   LANCET

Anesthetic effects on susceptibility to cortical spreading depression

(2012) Chiho Kudo et al.   NEUROPHARMACOLOGY

Effect of anesthesia and cerebral blood flow on neuronal injury in a rat middle cerebral artery occlusion (MCAO) model

(2012) C. Bleilevens et al.   EXPERIMENTAL BRAIN RESEARCH

Spreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortex

(2011) J. P. Dreier et al.   BRAIN

The economic cost of brain disorders in Europe

(2011) J. Olesen et al.   EUROPEAN JOURNAL OF NEUROLOGY

The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease

(2011) Jens P Dreier   NATURE MEDICINE

The role of pannexin hemichannels in the anoxic depolarization of hippocampal pyramidal cells

(2010) Christian Madry et al.   BRAIN

Spreading depolarizations cycle around and enlarge focal ischaemic brain lesions

(2010) Hajime Nakamura et al.   BRAIN

Experimental and Preliminary Clinical Evidence of an Ischemic Zone with Prolonged Negative DC Shifts Surrounded by a Normally Perfused Tissue Belt with Persistent Electrocorticographic Depression

(2010) Ana I Oliveira-Ferreira et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dynamic in vivo imaging of cerebral blood flow and blood–brain barrier permeability

(2009) Ofer Prager et al.   NEUROIMAGE

Preliminary Evidence That Ketamine Inhibits Spreading Depolarizations in Acute Human Brain Injury

(2009) Oliver W. Sakowitz et al.   STROKE

Spreading depolarizations occur in human ischemic stroke with high incidence

(2008) Christian Dohmen et al.   ANNALS OF NEUROLOGY

Ketamine successfully terminates malignant status epilepticus

(2008) Harald Prüss et al.   EPILEPSY RESEARCH

Transient Widespread Blood—Brain Barrier Alterations after Cerebral Photothrombosis as Revealed by Gadofluorine M-Enhanced Magnetic Resonance Imaging

(2008) Guido Stoll et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The blood–brain barrier is continuously open for several weeks following transient focal cerebral ischemia

(2008) D. Strbian et al.   NEUROSCIENCE