Proteomic Profiling of Plasma and Brain Tissue from Alzheimer’s Disease Patients Reveals Candidate Network of Plasma Biomarkers

Validation of Plasma Proteomic Biomarkers Relating to Brain Amyloid Burden in the EMIF-Alzheimer’s Disease Multimodal Biomarker Discovery Cohort

(2020) Sarah Westwood et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma P-tau181 in Alzheimer’s disease: relationship to other biomarkers, differential diagnosis, neuropathology and longitudinal progression to Alzheimer’s dementia

(2020) Shorena Janelidze et al.   NATURE MEDICINE

Diagnostic value of plasma phosphorylated tau181 in Alzheimer’s disease and frontotemporal lobar degeneration

(2020) Elisabeth H. Thijssen et al.   NATURE MEDICINE

Inhibition of Stat3‐mediated astrogliosis ameliorates pathology in an Alzheimer's disease model

(2019) Nicole Reichenbach et al.   EMBO Molecular Medicine

Blood-based molecular biomarkers for Alzheimer’s disease

(2019) Henrik Zetterberg et al.   Molecular Brain

Plasma biomarkers of astrocytic and neuronal dysfunction in early‐ and late‐onset Alzheimer's disease

(2019) Fanny M. Elahi et al.   Alzheimers & Dementia

Plasma phospho-tau181 increases with Alzheimer's disease clinical severity and is associated with tau- and amyloid-positron emission tomography

(2018) Michelle M. Mielke et al.   Alzheimers & Dementia

Plasma amyloid levels within the Alzheimer's process and correlations with central biomarkers

(2018) Olivier Hanon et al.   Alzheimers & Dementia

Serum haptoglobin in Chinese patients with Alzheimer’s disease and mild cognitive impairment: A case-control study

(2018) Cen-Jing Zhu et al.   BRAIN RESEARCH BULLETIN

Amyloid blood biomarker detects Alzheimer's disease

(2018) Andreas Nabers et al.   EMBO Molecular Medicine

Selenium, selenoprotein P, and Alzheimer's disease: is there a link?

(2018) Nikolay Solovyev et al.   FREE RADICAL BIOLOGY AND MEDICINE

Assay of Plasma Phosphorylated Tau Protein (Threonine 181) and Total Tau Protein in Early-Stage Alzheimer’s Disease

(2018) Che-Chuan Yang et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma Amyloid-β (Aβ42) Correlates with Cerebrospinal Fluid Aβ42 in Alzheimer’s Disease

(2018) Charlotte E. Teunissen et al.   JOURNAL OF ALZHEIMERS DISEASE

DNA methylation of TOMM40-APOE-APOC2 in Alzheimer’s disease

(2018) Yvonne Shao et al.   JOURNAL OF HUMAN GENETICS

Common proteomic profiles of induced pluripotent stem cell-derived three-dimensional neurons and brain tissue from Alzheimer patients

(2018) Mei Chen et al.   Journal of Proteomics

High performance plasma amyloid-β biomarkers for Alzheimer’s disease

(2018) Akinori Nakamura et al.   NATURE

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

(2018) Melanie D. Sweeney et al.   Nature Reviews Neurology

Candidate Blood Proteome Markers of Alzheimer's Disease Onset and Progression: A Systematic Review and Replication Study

(2018) Steven J. Kiddle et al.   JOURNAL OF ALZHEIMERS DISEASE

Apolipoprotein C-III is an Amyloid-β-Binding Protein and an Early Marker for Alzheimer's Disease

(2018) Yao-Hsiang Shih et al.   JOURNAL OF ALZHEIMERS DISEASE

Prognostic Polypeptide Blood Plasma Biomarkers of Alzheimer's Disease Progression

(2018) Hongqian Yang et al.   JOURNAL OF ALZHEIMERS DISEASE

Plasma Protein Profiling of Mild Cognitive Impairment and Alzheimer's Disease Across Two Independent Cohorts

(2018) Julia Muenchhoff et al.   JOURNAL OF ALZHEIMERS DISEASE

Biomarkers for Alzheimer's disease: current status and prospects for the future

(2018) K. Blennow et al.   JOURNAL OF INTERNAL MEDICINE

Complement protein C5a enhances the β-amyloid-induced neuro-inflammatory response in microglia in Alzheimer’s disease

(2018) Xiao-qun An et al.   M S-MEDECINE SCIENCES

A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease

(2018) Hedieh Shahpasand-Kroner et al.   Alzheimers Research & Therapy

Proteomics Analysis of Blood Serums from Alzheimer’s Disease Patients Using iTRAQ Labeling Technology

(2017) Liming Shen et al.   JOURNAL OF ALZHEIMERS DISEASE

Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer’s disease and down syndrome

(2017) Harutsugu Tatebe et al.   Molecular Neurodegeneration

Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer’s disease

(2017) Yuki Kitamura et al.   NEUROLOGICAL RESEARCH

Opposing Effects of Oxygen Regulation on Kallistatin Expression: Kallistatin as a Novel Mediator of Oxygen-Induced HIF-1-eNOS-NO Pathway

(2017) Julie Chao et al.   Oxidative Medicine and Cellular Longevity

Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy

(2016) Abby Keable et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Structure and Expression of Different Serum Amyloid A (SAA) Variants and their Concentration-Dependent Functions During Host Insults

(2016) Mieke Buck et al.   CURRENT MEDICINAL CHEMISTRY

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Alpha-2 macroglobulin in Alzheimer’s disease: a marker of neuronal injury through the RCAN1 pathway

(2016) V R Varma et al.   MOLECULAR PSYCHIATRY

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3–induced outside-in signaling and clusterin release

(2016) Lili Donner et al.   Science Signaling

Platelets contribute to amyloid-β aggregation in cerebral vessels through integrin αIIbβ3–induced outside-in signaling and clusterin release

(2016) Lili Donner et al.   Science Signaling

Association between Serum Haptoglobin and the Pathogenesis of Alzheimer's Disease

(2015) In-Uk Song et al.   INTERNAL MEDICINE

Emerging functions of serum amyloid A in inflammation

(2015) Richard D. Ye et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immune attack: the role of inflammation in Alzheimer disease

(2015) Frank L. Heppner et al.   NATURE REVIEWS NEUROSCIENCE

Protective properties of lysozyme on β-amyloid pathology: implications for Alzheimer disease

(2015) Linda Helmfors et al.   NEUROBIOLOGY OF DISEASE

Decreased expression of the APOA1–APOC3–APOA4 gene cluster is associated with risk of Alzheimer’s disease

(2015) Qiao Lin et al.   Drug Design Development and Therapy

Plasma proteins predict conversion to dementia from prodromal disease

(2014) Abdul Hye et al.   Alzheimers & Dementia

Platelet-Rich Preparations to Improve Healing. Part II: Platelet Activation and Enrichment, Leukocyte Inclusion, and Other Selection Criteria

(2014) Vicki L Davis et al.   Journal of Oral Implantology

Oxidative Stress in Alzheimer’s Disease: Why Did Antioxidant Therapy Fail?

(2014) Torbjörn Persson et al.   Oxidative Medicine and Cellular Longevity

Plasma protein profiling of Mild Cognitive Impairment and Alzheimer’s disease using iTRAQ quantitative proteomics

(2014) Fei Song et al.   Proteome Science

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

(2013) Bin Zhang et al.   CELL

A blood-based predictor for neocortical Aβ burden in Alzheimer’s disease: results from the AIBL study

(2013) S C Burnham et al.   MOLECULAR PSYCHIATRY

CD33 Alzheimer's disease locus: altered monocyte function and amyloid biology

(2013) Elizabeth M Bradshaw et al.   NATURE NEUROSCIENCE

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

Evaluation of Plasma Proteomic Data for Alzheimer Disease State Classification and for the Prediction of Progression From Mild Cognitive Impairment to Alzheimer Disease

(2012) Daniel A. Llano et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Plasma Biomarkers Associated With the Apolipoprotein E Genotype and Alzheimer Disease

(2012) Holly D. Soares   ARCHIVES OF NEUROLOGY

Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease

(2012) W. T. Hu et al.   NEUROLOGY

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Amyloid-Beta (Aβ) D7H Mutation Increases Oligomeric Aβ42 and Alters Properties of Aβ-Zinc/Copper Assemblies

(2012) Wei-Ting Chen et al.   PLoS One

Qualification of the analytical and clinical performance of CSF biomarker analyses in ADNI

(2011) Leslie M. Shaw et al.   ACTA NEUROPATHOLOGICA

Genetic Ablation of Apolipoprotein A-IV Accelerates Alzheimer's Disease Pathogenesis in a Mouse Model

(2011) Yujie Cui et al.   AMERICAN JOURNAL OF PATHOLOGY

Complement in the brain

(2011) Robert Veerhuis et al.   MOLECULAR IMMUNOLOGY

Genetic variation in APOE cluster region and Alzheimer's disease risk

(2011) Sebastián Cervantes et al.   NEUROBIOLOGY OF AGING

Plasma Biomarkers of Brain Atrophy in Alzheimer's Disease

(2011) Madhav Thambisetty et al.   PLoS One

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

Cerebral amyloid angiopathy pathology and cognitive domains in older persons

(2010) Zoe Arvanitakis et al.   ANNALS OF NEUROLOGY

Brain lipid sensing and nervous control of energy balance

(2010) S. Migrenne et al.   DIABETES & METABOLISM

Review: Sporadic cerebral amyloid angiopathy

(2010) J. Attems et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Brain amyloid β protein and memory disruption in Alzheimer’s disease

(2010) Weiming Xia   Neuropsychiatric Disease and Treatment

A Specific Enzyme-Linked Immunosorbent Assay for Measuring β-Amyloid Protein Oligomers in Human Plasma and Brain Tissue of Patients With Alzheimer Disease

(2009) Weiming Xia et al.   ARCHIVES OF NEUROLOGY

Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer’s disease

(2009) Madhav Thambisetty et al.   JOURNAL OF NEUROLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Immune versus thrombotic stimulation of platelets differentially regulates signalling pathways, intracellular protein-protein interactions, and α-granule release

(2009) Sybille Rex et al.   THROMBOSIS AND HAEMOSTASIS

Role of kallistatin in prevention of cardiac remodeling after chronic myocardial infarction

(2008) Lin Gao et al.   LABORATORY INVESTIGATION

Expression of interleukin-18 is increased in the brains of Alzheimer's disease patients

(2007) Johanna Ojala et al.   NEUROBIOLOGY OF AGING