Synthesis of the Thomsen-Friedenreich-antigen (TF-antigen) and binding of Galectin-3 to TF-antigen presenting neo-glycoproteins

Thiodigalactoside–Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors

(2018) Hao Zhang et al.   BIOCONJUGATE CHEMISTRY

Poly-N-Acetyllactosamine Neo-Glycoproteins as Nanomolar Ligands of Human Galectin-3: Binding Kinetics and Modeling

(2018) Ladislav Bumba et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular Recognition of a Thomsen-Friedenreich Antigen Mimetic Targeting Human Galectin-3

(2018) Sabrina Santarsia et al.   ChemMedChem

Galectin–Carbohydrate Interactions in Biomedicine and Biotechnology

(2018) Dominic Laaf et al.   TRENDS IN BIOTECHNOLOGY

Synthesis of Glycosides by Glycosynthases

(2017) Marc Hayes et al.   MOLECULES

Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

(2016) Tamara Delaine et al.   CHEMBIOCHEM

Synthetic glycoconjugates inhibitors of tumor-related galectin-3: an update

(2016) Vanessa Leiria Campo et al.   GLYCOCONJUGATE JOURNAL

Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides

(2015) Maria C. Rodriguez et al.   BIOCHEMISTRY

Combination of Glycosyltransferases and a Glycosynthase in Sequential and One-Pot Reactions for the Synthesis of Type 1 and Type 2N-Acetyllactosamine Oligomers

(2015) Manja Henze et al.   ChemCatChem

Structural Basis Underlying the Binding Preference of Human Galectins-1, -3 and -7 for Galβ1-3/4GlcNAc

(2015) Tung-Ju Hsieh et al.   PLoS One

Inhibitors of Galectins and Implications for Structure-Based Design of Galectin-Specific Therapeutics

(2014) Helen Blanchard et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Characterization of a Galactosynthase Derived fromBacillus circulansβ-Galactosidase: Facile Synthesis ofD-Lacto- andD-Galacto-N-bioside

(2014) Chao Li et al.   CHEMBIOCHEM

Glycomimetics versus Multivalent Glycoconjugates for the Design of High Affinity Lectin Ligands

(2014) Samy Cecioni et al.   CHEMICAL REVIEWS

Rational design of a glycosynthase by the crystal structure of β-galactosidase from Bacillus circulans (BgaC) and its use for the synthesis of N-acetyllactosamine type 1 glycan structures

(2014) Manja Henze et al.   JOURNAL OF BIOTECHNOLOGY

Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3

(2013) Helen Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Galectin-3 Interactions with Glycosphingolipids

(2013) Patrick M. Collins et al.   JOURNAL OF MOLECULAR BIOLOGY

Synthesis of nucleotide-activated disaccharides with recombinant β3-galactosidase C from Bacillus circulans

(2013) Claudia Kamerke et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Cod glycopeptide with picomolar affinity to galectin-3 suppresses T-cell apoptosis and prostate cancer metastasis

(2013) P. Guha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Recognition of the Thomsen-Friedenreich Antigen–Threonine Conjugate by Adhesion/Growth Regulatory Galectin-3: Nuclear Magnetic Resonance Studies and Molecular Dynamics Simulations

(2012) Austin B. Yongye et al.   BIOCHEMISTRY

Glycosynthases as tools for the production of glycan analogs of natural products

(2012) Beatrice Cobucci-Ponzano et al.   NATURAL PRODUCT REPORTS

The Tn Antigen-Structural Simplicity and Biological Complexity

(2011) Tongzhong Ju et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibition of Galectins with Small Molecules

(2011) Christopher T. Öberg et al.   CHIMIA

Structural Basis for Distinct Binding Properties of the Human Galectins to Thomsen-Friedenreich Antigen

(2011) Cheng-Feng Bian et al.   PLoS One

Formation of Homooligosaccharides Using Base-Promoted Glycosylation of Unprotected Glycosyl Fluorides

(2010) Andreas Steinmann et al.   MACROMOLECULES

Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis

(2010) Qicheng Zhao et al.   Molecular Cancer

Analysis and Optimization of Copper-Catalyzed Azide–Alkyne Cycloaddition for Bioconjugation

(2009) Vu Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Circulating Galectin-3 Promotes Metastasis by Modifying MUC1 Localization on Cancer Cell Surface

(2009) Q. Zhao et al.   CANCER RESEARCH

Chemical cross-linking with NHS esters: a systematic study on amino acid reactivities

(2009) Stefanie Mädler et al.   JOURNAL OF MASS SPECTROMETRY

Chances and pitfalls of chemical cross-linking with amine-reactive N-hydroxysuccinimide esters

(2008) Stefan Kalkhof et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens

(2008) Sean R. Stowell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY