Article
Biochemistry & Molecular Biology
Fei Peng, Linan Chen, Xiuping Wang, Zuoqing Yu, Caihong Cheng, Yuedong Yang
Summary: Chestnut bur polyphenol extract (CBPE) exhibits antibacterial activity against Shigella dysenteriae by disrupting cell membrane and wall, and interfering with multiple metabolic pathways.
Article
Food Science & Technology
Jin-Wei Zhou, Peng-Cheng Ji, Chang-Yao Wang, Yu-Jie Yang, Xin-Yu Zhao, Hao-Zhe Tang
Summary: The anti-virulence potential and mechanism of Perilla frutescens-derived dihydrocuminyl aldehyde (DCA) against Pseudomonas aeruginosa XZ01 were investigated using transcriptome sequencing and metabolomics. DCA effectively reduced the production of virulence factors and disrupted biofilm formation. Mechanistically, DCA down-regulated quorum sensing-related genes, increased membrane permeability, and suppressed efflux systems, leading to heightened susceptibility to nisin and metabolic disorders.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2023)
Review
Microbiology
Bandita Dutta, Dibyajit Lahiri, Moupriya Nag, Rose Abukhader, Tanmay Sarkar, Siddhartha Pati, Vijay Upadhye, Soumya Pandit, Mohamad Faiz Mohd Amin, Abdel Rahman Mohammad Said Al Tawaha, Manoj Kumar, Rina Rani Ray
Summary: This review highlights the importance of using multi-omics methods for improving the quality of food products, and discusses the recent technologies used for this purpose.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Plant Sciences
Xin Gong, Kaijie Qi, Juanli Chen, Liangyi Zhao, Zhihua Xie, Xin Yan, Shahrokh Khanizadeh, Shaoling Zhang, Shutian Tao
Summary: This study performed phenomic analysis on stone cells and their associated vascular bundles near the pear fruit core. Transcriptomic, proteomic, and metabolomic analyses revealed the positive regulation of biological processes related to lignin deposition in stone cells near the fruit core. Moreover, a key transcription factor, PbbZIP48, was identified as a regulator of lignin biosynthesis in stone cells. These findings provide insight into the mechanism of lignified stone cell formation in pear fruit.
Article
Plant Sciences
Jiaoke Zeng, Chuying Chen, Ming Chen, Jinyin Chen
Summary: Naringin treatment delays citrus fruit decay and maintains fruit quality by promoting metabolite accumulation and upregulating differentially expressed genes in the phenylpropanoid and flavonoid biosynthesis pathways.
FRONTIERS IN PLANT SCIENCE
(2022)
Article
Plant Sciences
Chunmei Bai, Caie Wu, Lili Ma, Anzhen Fu, Yanyan Zheng, Jiawei Han, Changbao Li, Shuzhi Yuan, Shufang Zheng, Lipu Gao, Xinhua Zhang, Qing Wang, Demei Meng, Jinhua Zuo
Summary: Tomato is an important vegetable crop and a model plant for studying fruit ripening. Low temperatures delay the ripening process and inhibit flavor compounds and ethylene production in tomatoes. Transcriptomics and metabolomics analyses revealed the effects of storage temperature on physiological changes in tomato fruit after harvest.
HORTICULTURAL PLANT JOURNAL
(2023)
Article
Agriculture, Multidisciplinary
Ping Li, Junru Long, Genxiang Bai, Jian Zhang, Yunsheng Cha, Wenjie Gao, Xinbo Luan, Lianzhang Wu, Mingxing Mu, Edward J. Kennelly, Penghui Gao, Yuanyuan Liu, Lirong Sun, Quan Yang, Guanhua Wang, Zhijian Yu, Juncai He, Yi Yang, Jian Yan
Summary: Amomum tsao-ko is a valuable plant with high potential in food additives and drug development due to its rich bioactive constituents. Through metabolomics and transcriptomics research, it was found that the chemical composition of A. tsao-ko fruit varies in different stages of ripening, with a trend of decrease or increase in diarylheptanoids during fruit development. Several plant hormone signaling pathways and biosynthetic pathways were found to be associated with fruit ripening, and 10 diarylheptanoids, including three new compounds, were isolated and identified. Candidate genes related to diarylheptanoids biosynthesis were obtained through coexpression network analysis and phylogenetic analysis, and two key genes were verified. This integrative approach provides valuable insights into the gene regulation and networking associated with the biosynthesis of characteristic diarylheptanoids in A. tsao-ko, which can contribute to improving its quality as food and medicine.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Fen Wang, Shunfeng Ge, Xinxiang Xu, Yue Xing, Xin Du, Xin Zhang, Mengxue Lv, Jingquan Liu, Zhanling Zhu, Yuanmao Jiang
Summary: The excessive application of nitrogen fertilizer in Chinese apple production was found to decrease the content of soluble sugar and flavonoids in fruits, leading to poor fruit quality. High nitrogen levels also altered the nitrogen, carbon content, and C/N ratio of apple fruits. The study revealed that high nitrogen inhibited the accumulation of carbohydrates and flavonoids in fruits, and promoted the synthesis of amino acids using more carbon skeletons. This insight provides new understanding on the effects of high nitrogen on fruit quality.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Review
Agriculture, Multidisciplinary
Sagar Datir, Sharon Regan
Summary: Mango is a nutritionally important fruit with high nutritive value and attractive aroma. Studies have used omics techniques to understand the physiological, biochemical, and molecular basis of mango fruit development, maturity, ripening, and storage, in order to enhance fruit quality. Key genes, metabolites, proteins, and quantitative trait loci associated with mango fruit quality have been identified. This review summarizes the applications of omics techniques in understanding mango fruit physiology and their potential usefulness in the future.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Food Science & Technology
Wenkai Duan, Wanlu Shao, Weida Lin, Ling Yuan, Qiuwei Lu, Luxi Chen, Lyuben Zagorchev, Junmin Li
Summary: Fragaria pentaphylla is a perennial herb with red or white fruit morphs; red fruits have higher quality with abundant flavonoids, free amino acids, and vitamins compared to white fruits; red fruits contain more anthocyanins, procyanidin, and flavonoids than white fruits.
Article
Chemistry, Applied
Gerardo Nunez-Lillo, Excequel Ponce, Camila Arancibia-Guerra, Sebastien Carpentier, Alegria Carrasco-Pancorbo, Lucia Olmo-Garcia, Rosana Chirinos, David Campos, Reinaldo Campos-Vargas, Claudio Meneses, Romina Pedreschi
Summary: This study aims to understand the mechanisms behind the color and softening of avocado exocarp. By integrating omics datasets, including transcriptomics, proteomics, and metabolomics, the researchers identified transcription factors and potential biomarkers associated with color and softening control in avocados.
Article
Plant Sciences
Baolian Ma, Shilin Yang, Ting Tan, Junmao Li, Xiaoyong Zhang, Hui Ouyang, Mingzhen He, Yulin Feng
Summary: Akebiae Fructus effectively alleviated primary dysmenorrhea symptoms, regulated metabolic disorders, and controlled related gene expression. The study may provide clues for further research on Akebiae Fructus treatment for primary dysmenorrhea.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Agronomy
Excequel Ponce, Gerardo Nunez-Lillo, Camila Bravo, Juan Vidal, Patricio Tapia -Reyes, Claudio Meneses, Romina Pedreschi, Claudia Fuentealba
Summary: Surface pitting is a major quality problem in sweet cherries during storage. This study analyzed the cell wall disassembly and metabolic/transcriptomic changes in two cultivars with different susceptibilities to pitting. The results showed that 'Sweetheart' cherries had more severe damage compared to 'Bing' cherries, and the varietal differences during cold storage were significant. Metabolomics analysis identified compounds related to abiotic stress response, while transcriptomics revealed differential expression of stress-related hormones and cell wall remodeling-related genes. The susceptibility to surface pitting in sweet cherries is attributed to the varietal response to cold storage rather than the mechanical stress of pitting induction.
POSTHARVEST BIOLOGY AND TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Kanghua Song, Xiumei Zhang, Jiameng Liu, Quansheng Yao, Yixing Li, Xiaowan Hou, Shenghui Liu, Xunxia Qiu, Yue Yang, Li Chen, Keqian Hong, Lijing Lin
Summary: The yellowing and quality improvement of pineapple fruit during ripening are associated with increases in total phenols and flavones, as well as decreases in lignin and total acid contents. The biosynthesis of plant secondary metabolites, particularly the flavonol, flavonoid, and phenylpropanoid pathways, plays a pivotal role in fruit yellowing. Furthermore, a comprehensive regulatory network involving genes related to the metabolism of flavones, flavonols, lignin, and organic acids was proposed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Plant Sciences
Yang Chen, Leting Si, Jinghui Zhang, Hengyuan Yu, Xuesong Liu, Yong Chen, Yongjiang Wu
Summary: Shikonin demonstrates significant antitumor potency in colon cancer by affecting cell cycle and inducing apoptosis. Transcriptomics and metabolomics analysis reveal perturbed pathways related to purine metabolism, arginine biosynthesis, pyrimidine metabolism, urea cycle, and amino acid metabolism. The up-regulated expression of proteins vital for arginine biosynthesis is validated, and the genes participating in purine metabolism and arginine biosynthesis are further determined by RT-qPCR.
Article
Biochemistry & Molecular Biology
Jose David Sanchez-Martinez, Ana Rita Garcia, Gerardo Alvarez-Rivera, Alberto Valdes, Maria Alexandra Brito, Alejandro Cifuentes
Summary: Agrifood by-products and microalgae are rich sources of bioactive compounds with neuroprotective properties, but their effectiveness is limited by the blood-brain barrier (BBB). In this study, green extracts from various sources were tested for their permeability across an in vitro BBB model. Results showed that neuroprotective compounds like terpenoids, phytosterols, and phenolic compounds had high permeability. These findings support the potential use of these natural extracts as functional ingredients in food supplements or nutraceuticals with neuroprotective claims.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Davide Liberti, Paola Imbimbo, Enrica Giustino, Luigi D'Elia, Giarita Ferraro, Angela Casillo, Anna Illiano, Gabriella Pinto, Maria Chiara Di Meo, Gerardo Alvarez-Rivera, Maria Michela Corsaro, Angela Amoresano, Armando Zarrelli, Elena Ibanez, Antonello Merlino, Daria Maria Monti
Summary: A biorefinery approach was developed to extract high-value bioproducts, including exopolysaccharides, phycoerythrin, and β-carotene, from the culture of Porphyridium cruentum.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Biochemistry & Molecular Biology
Juliana A. Barreto Peixoto, Gerardo alvarez-Rivera, Anabela S. G. Costa, Susana Machado, Alejandro Cifuentes, Elena Ibanez, M. Beatriz P. P. Oliveira, Rita C. Alves
Summary: This study investigated the antioxidant potential, phenolic profile, and free amino acid profile of lemon verbena infusions from different commercial brands. Various assays showed that the infusions exhibited high antioxidant activity, which was correlated with total phenolics and total flavonoid contents. Phenylalanine also appeared to have an impact on the antioxidant activity. Significant differences were found among the evaluated parameters for one of the commercial brands, possibly due to different geographical origins. Overall, lemon verbena infusions contain a variety of bioactive compounds with therapeutic potential.
Article
Environmental Sciences
Blanca Huidobro-Lopez, Carlos Leon, Isabel Lopez-Heras, Virtudes Martinez-Hernandez, Leonor Nozal, Antonio L. Crego, Irene de Bustamante
Summary: Vegetation filters use natural attenuation processes in soil to remove contaminants from wastewater and provide environmental benefits. However, this practice may introduce emerging contaminants into the environment. This study tested the use of woodchips and biochar in column experiments to improve the system, and found that biochar enhanced contaminant attenuation and resulted in fewer metabolites, while woodchips reduced attenuation and led to more metabolites, likely due to shorter retention times.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Chemistry, Analytical
Brenda Lee Simas Porto, Alberto Valdes, Alejandro Cifuentes, Gerardo Alvarez-Rivera
Summary: This article revisits recent articles that have used capillary electromigration techniques to study various phytochemicals between 2018 and 2021. The manuscript is divided based on the different separation methods used, and the main aspects of each application are briefly discussed, including sample preparation, advantages and disadvantages of the developed methods, problems encountered during the process, and ways to solve them.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Agriculture, Dairy & Animal Science
Victoria Pena-Delgado, Melissa Carvajal-Serna, Manuel Fondevila, Maria A. Martin-Cabrejas, Yolanda Aguilera, Gerardo Alvarez-Rivera, Jose A. Abecia, Adriana Casao, Rosaura Perez-Pe
Summary: The aim of this study was to evaluate the effect of a phytomelatonin-rich diet on ram sperm quality and seminal plasma composition. The results showed that the diet, including grape pulp, pomegranate and tomato pomaces, increased melatonin levels in seminal plasma, improved sperm viability and morphology, and protected sperm cells against oxidative damage.
Review
Biochemical Research Methods
Gloria Dominguez-Rodriguez, Lidia Montero, Miguel Herrero, Alejandro Cifuentes, Maria Castro-Puyana
Summary: This study provides an overview of the main applications of capillary electromigration (CE) methods in food analysis and Foodomics. Papers published between March 2021 and March 2023 were reviewed. The study highlights the various CE methods that have been developed and utilized for the analysis of different molecules in food and beverages. Additionally, new CE procedures for chiral separation, evaluating the effects of food processing, and recent developments in microchip CE and Foodomics applications are discussed.
Article
Food Science & Technology
Jose David Sanchez-Martinez, Alejandro Cifuentes, Alberto Valdes
Summary: Citrus sinensis by-products are found to be a promising source of neuroprotective molecules. A pressurized liquid extract of Citrus by-products (PLE100) has been extensively characterized and shown to have a dose-dependent neuroprotective effect against Alzheimer's disease (AD) in a Caenorhabditis elegans model. Transcriptomics and metabolomics analysis provide new evidence for the underlying protection mechanisms of this extract.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Biochemical Research Methods
Alberto Marcos, Carlos Leon, Mario Moreno-Fernandez, Florentina Castro-Rubio, Lucia Garrido-Matilla, Leonor Nozal, Emilio Ambrosio, Antonio L. Crego
Summary: This study reports the first untargeted metabolomic study in brain tissues to investigate the possible neurobiological effects of combined consumption of ethanol and cocaine. Results showed altered metabolic pathways involved in multiple functions.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Biochemistry & Molecular Biology
Joao Victor Basolli Borsatto, Edvaldo Vasconcelos Soares Maciel, Alejandro Cifuentes, Fernando Mauro Lancas
Summary: Graphene-based sorbents were used as extraction and analytical columns in a column-switching system. The system showed successful application for pyriproxyfen analysis but was not suitable for abamectin B1a analysis. The SiGO-C18ec column presented significant tailing compared to a C18 column in a similar approach.
Article
Pharmacology & Pharmacy
Maria Taboada-Alquerque, Danilo Pajaro-Valenzuela, Karina Caballero-Gallardo, Alejandro Cifuentes, Elena Ibanez, Maicol Ahumedo-Monterrosa, Elena E. Stashenko, Jesus Olivero-Verbel
Summary: A natural compound called carnosol found in rosemary has been identified as a potential anti-tumor and anti-inflammatory agent. Through network pharmacology, plausible human targets for carnosol were identified, and it was found to be closely related to infection and inflammation. These findings suggest that carnosol may exert its effects through inducing an immuno-inflammatory response.
SCIENTIA PHARMACEUTICA
(2023)
Review
Chemistry, Analytical
Gerson-Dirceu Lopez, Gerardo Alvarez-Rivera, Chiara Carazzone, Elena Ibanez, Chad Leidy, Alejandro Cifuentes
Summary: Natural carotenoids have important applications in pharmaceutical, cosmetic, nutraceutical, and food industries. The use of bacteria for carotenoid production has gained much attention in recent years. This review summarizes the methods for extracting and identifying bacterial carotenoids and highlights the use of high-performance liquid chromatography-mass spectrometry (HPLC-MS) for analysis and identification. The potential commercial use of these carotenoids is also discussed.
CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY
(2023)
Article
Food Science & Technology
Yonghong Ye, Songyan Zheng, Yuanxing Wang
Summary: In this study, the changes of aroma components in Gannan navel orange during growth were systematically studied using HS-SPME-GC-MS. Key aroma components and markers were identified. These findings contribute to a better understanding of the dynamic variation of aroma compounds during navel orange growth and have potential for industrial applications.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Jia Xu, Yayuan Zhang, Mengke Zhang, Xinlin Wei, Yiming Zhou
Summary: This study evaluated the effects of glucosamine selenium on summer-autumn tea, showing that it can enhance nutritional quality, improve sensory characteristics, and increase plant adaptation to environmental changes and abiotic stresses.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Yuanming Chu, Zhaoyang Ding, Jing Xie
Summary: This study investigated the use of ice glazing containing D-sodium erythorbate (DSE) and vacuum packaging to maintain the quality of large yellow croaker during frozen storage. The results showed that vacuum packaging effectively inhibited ice crystal growth and minimized water loss, while the combination of vacuum packaging and 0.3% DSE-infused ice glazing maintained freshness indicators at low levels throughout the 300-day storage period. This combination was considered the most effective in preserving the quality of the fish.
FOOD RESEARCH INTERNATIONAL
(2024)
Review
Food Science & Technology
Md. Ashikur Rahman, Shirin Akter, Md. Ashrafudoulla, Md. Anamul Hasan Chowdhury, A. G. M. Sofi Uddin Mahamud, Si Hong Park, Sang-Do Ha
Summary: This comprehensive review aims to provide insights into the mechanisms and key factors influencing biofilm formation by A. hydrophila in the food industry. It explores the molecular processes involved in various stages of biofilm formation and investigates the impact of intrinsic factors and environmental conditions on biofilm architecture and resilience. The article also highlights the potential of bibliometric analysis in conceptualizing the research landscape and identifying knowledge gaps in A. hydrophila biofilm research.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Chujing Wang, Wenni Tian, Zengliu Song, Qun Wang, Yong Cao, Jie Xiao
Summary: Solid lipid ratio in emulsions has significant effects on colloidal stability, mucus permeability, and bioavailability in vivo. Higher solid lipid ratio improves intestinal stability but reduces mucus permeability.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Dacai Zhong, Liping Kang, Juan Liu, Xiang Li, Li Zhou, Luqi Huang, Zidong Qiu
Summary: In this study, a novel online extraction electrospray ionization mass spectrometry method was developed to comprehensively characterize complex foods. Meanwhile, a characteristic marker screening method and chemometrics modeling were used for the accurate authentication of highly-similar foods. This research has significant implications for ensuring food quality and safety.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Qiannan Zhao, Jinyi Yang, Jiahui Li, Lei Zhang, Xiaohai Yan, Tianli Yue, Yahong Yuan
Summary: This study investigated the transport and hypoglycemic effects of phenolics in mulberry leaves using an in vitro digestion model. The results showed that digested phenolics had higher absorbability and could inhibit glucose digestion and absorption. Phenolics also regulated glucose metabolism. Luteoforol and p-coumaric acid were found to be the primary phenolics strongly correlated with the hypoglycemic ability of mulberry leaves.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Yanyun Cao, Qingling Wang, Jinou Lin, Yin-Yi Ding, Jianzhong Han
Summary: This study investigated the effects of gallic acid (GA) and epigallocatechin gallate (EGCG) at different ratios on the gel properties of calcium induced-whey protein emulsion gel. It was found that GA and EGCG could promote gel formation, increase gel strength, and delay the release of emulsified oil droplets.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Monique Martins Strieder, Vitor Lacerda Sanches, Mauricio Ariel Rostagno
Summary: This study proposed an integrated and automated procedure for extracting, separating, and quantifying bioactive compounds from coffee co-products. By optimizing the extraction, separation, and analysis method, real-time analysis was achieved. The results suggest that coupling different techniques can efficiently extract, separate, and analyze phenolic compounds, providing an integrated method to produce high-added value ingredients for various applications.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Kyu Sang Sim, Hyoyoung Kim, Suel Hye Hur, Tae Woong Na, Ji Hye Lee, Ho Jin Kim
Summary: Geographical origin plays a crucial role in determining the quality and safety of agricultural products. In this study, ICP analysis was used to determine the inorganic elemental content of onions and identify their geographical origin. Chemometric methods were applied to analyze the ICP results, and the accuracy of distinguishing between Korean and Chinese onions was found to be excellent. The findings suggest that this method can be beneficial for identifying agricultural products.
FOOD RESEARCH INTERNATIONAL
(2024)