Article
Geriatrics & Gerontology
Aline Mendes, Francois R. Herrmann, Samuel Perivier, Gabriel Gold, Christophe E. Graf, Dina Zekry
Summary: This study found a high prevalence of delirium in older patients admitted with COVID-19, with preexisting cognitive impairment as the main risk factor for developing delirium. Delirium was associated with significantly higher in-hospital mortality among these patients.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2021)
Article
Infectious Diseases
Sara Tehrani, Anna Killander, Per Astrand, Jan Jakobsson, Patrik Gille-Johnson
Summary: This study investigated demographics, comorbidities, and death rate in hospitalized COVID-19 patients and found that functional status may be a better predictor of poor outcomes. Increasing age, chronic kidney disease, and previous stroke were identified as risk factors for death in hospitalized patients with COVID-19.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Microbiology
Jennifer M. Sasson, Joseph J. Campo, Rebecca M. Carpenter, Mary K. Young, Arlo Z. Randall, Krista Trappl-Kimmons, Amit Oberai, Christopher Hung, Joshua Edgar, Andy A. Teng, Jozelyn Pablo, Xiaowu Liang, Angela Yee, William A. Petri, David Camerini
Summary: The study revealed stronger antibody responses to specific SARS-CoV-2 epitopes in older patients, correlated with systemic cytokine responses. Additionally, some patients showed minimal antibody reactivity to SARS-CoV-2 antigens and experienced severe clinical outcomes.
Review
Geriatrics & Gerontology
H. D. W. T. Damayanthi, K. I. P. Prabani
Summary: Malnutrition is prevalent among older patients with COVID-19 and is associated with negative outcomes such as hospital deaths and transfer to intensive care units. Low levels of albumin, vitamin D, magnesium, vitamin B12, and Se status are also related to malnutrition, oxygen therapy, and survival of COVID-19 patients.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2021)
Article
Geriatrics & Gerontology
C. Liu, Z. Lu, L. Chen, X. Yang, J. Xu, H. Cui, M. Zhu
Summary: This study compared the association between GNRI and CONUT scores and malnutrition in older adult cancer patients, and examined their relationship with clinical outcomes. The study found that GNRI can be used to assess and predict malnutrition and poor clinical outcomes in older adult cancer patients.
JOURNAL OF NUTRITION HEALTH & AGING
(2022)
Article
Medicine, Research & Experimental
Gaetano Bergamaschi, Federica Borrelli de Andreis, Nicola Aronico, Marco Vincenzo Lenti, Chiara Barteselli, Stefania Merli, Ivan Pellegrino, Luigi Coppola, Elisa Maria Cremonte, Gabriele Croce, Francesco Morda, Francesco Lapia, Sara Ferrari, Alessia Ballesio, Alessandro Parodi, Francesca Calabretta, Maria Giovanna Ferrari, Federica Fumoso, Antonella Gentile, Federica Melazzini, Antonio Di Sabatino
Summary: COVID-19 patients commonly present with anemia, which is usually mild and inflammation-related, sometimes associated with iron and/or vitamin deficiencies. Determinants of hemoglobin concentration include erythrocyte sedimentation rate, serum cholinesterase, ferritin and protein concentrations, and number of chronic diseases affecting each patient. Hemoglobin concentration is not related to overall survival, but is influenced by red blood cell distribution width, age, lactate dehydrogenase, and the ratio of arterial partial oxygen pressure to inspired oxygen fraction.
CLINICAL AND EXPERIMENTAL MEDICINE
(2021)
Article
Geriatrics & Gerontology
Andy Sharma
Summary: This study aimed to model the probability of mortality from COVID-19 for older adults in the United States under best and worst case scenarios using simulations. The results showed that age, obesity, and hypertension were all associated with higher mortality risk, with age showing the strongest association. These findings can be useful for informing older adults about their mortality risks and rebuilding public trust.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2021)
Article
Nutrition & Dietetics
Quirin Notz, Johannes Herrmann, Tobias Schlesinger, Philipp Helmer, Stephan Sudowe, Qian Sun, Julian Hackler, Daniel Roeder, Christopher Lotz, Patrick Meybohm, Peter Kranke, Lutz Schomburg, Christian Stoppe
Summary: The study suggests that adequate levels of selenium and zinc may be clinically significant for maintaining an adequate immune response in critically ill patients with severe COVID-19 ARDS. Selenium supplementation significantly increased selenium levels and was negatively correlated with inflammatory markers, while positively correlated with certain immune markers.
Article
Medicine, General & Internal
Sedigheh Ahmadi, Donya Firoozi, Mohammad Dehghani, Morteza Zare, Zeinab Mehrabi, Maryam Ghaseminasab-Parizi, Seyed Jalil Masoumi
Summary: This study evaluated the application of NRS-2002 in critically ill COVID-19 patients and found that each unit increase in the NRS-2002 score was associated with a 354% increase in the odds of mortality. Increased malnutrition risk was linked with higher age and BUN levels and lower albumin and hematocrit levels.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
(2022)
Article
Nutrition & Dietetics
Constantin Bodolea, Andrada Nemes, Lucretia Avram, Rares Craciun, Mihaela Coman, Mihaela Ene-Cocis, Cristina Ciobanu, Dana Crisan
Summary: This study evaluated the effectiveness of four nutritional risk assessment tools and explored the predictive value of CT-derived fat tissue and muscle mass measurements in predicting in-hospital mortality of critically ill patients with COVID-19-associated ARDS. The results showed that the nutritional risk assessment tools can accurately predict mortality, while fat tissue and muscle mass were not associated with increased mortality risk.
Article
Nutrition & Dietetics
Busra Can, Nurdan Senturk Durmus, Sehnaz Olgun Yildizeli, Derya Kocakaya, Birkan Ilhan, Asli Tufan
Summary: This study aimed to investigate the utility of NRS-2002 and G8 screening tools in predicting clinical outcomes in older adults hospitalized with COVID-19. Results showed that older age and nutrition risk determined by NRS-2002 were independently associated with a higher risk of in-hospital mortality in older patients with COVID-19.
NUTRITION IN CLINICAL PRACTICE
(2022)
Review
Nutrition & Dietetics
Emilie Reber, Katja A. Schonenberger, Maria F. Vasiloglou, Zeno Stanga
Summary: Disease-related malnutrition is prevalent in cancer patients and can have negative impacts on outcomes. Early nutritional therapy has been shown to prevent, treat and limit the consequences of malnutrition, improving overall prognosis.
FRONTIERS IN NUTRITION
(2021)
Article
Nutrition & Dietetics
Dorothee Bedock, Julie Couffignal, Pierre Bel Lassen, Leila Soares, Alexis Mathian, Jehane P. Fadlallah, Zahir Amoura, Jean-Michel Oppert, Pauline Faucher
Summary: This study found that 28.6% of COVID-19 patients were malnourished 30 days after discharge, compared to 42.3% at admission. Early nutritional management helped some malnourished patients recover a normal nutritional status after discharge, but being transferred to intensive care units and high oxygen requirement during hospitalization were strong predictors of poor nutritional outcome.
Article
Nutrition & Dietetics
Andres Luciano Nicolas Martinuzzi, William Manzanares, Eliana Quesada, Maria Jimena Reberendo, Fernando Baccaro, Irina Aversa, Claudia Elisabeth Kecskes, Lorena Magnifico, Victoria Gonzalez, Daniela Bolzicco, Nancy Baraglia, Priscila Navarrete, Ezequiel Manrique, Maria Fernanda Cascaron, Ailen Dietrich, Jesica Asparch, Leticia Betiana Peralta, Cayetano Galletti, Maria Laura Capria, Yamila Lombi, Marian Cecilia Rodriguez, Camila Ester Luna, Sebastian Pablo Chapela
Summary: A multicenter study conducted in Argentinian ICUs highlighted the importance of nutritional status and specific nutritional assessment tools in predicting important clinical outcomes for COVID-19 patients.
NUTRICION HOSPITALARIA
(2021)
Article
Virology
Roohallah Alizadehsani, Zahra Alizadeh Sani, Mohaddeseh Behjati, Zahra Roshanzamir, Sadiq Hussain, Niloofar Abedini, Fereshteh Hasanzadeh, Abbas Khosravi, Afshin Shoeibi, Mohamad Roshanzamir, Pardis Moradnejad, Saeid Nahavandi, Fahime Khozeimeh, Assef Zare, Maryam Panahiazar, U. Rajendra Acharya, Sheikh Mohammed Shariful Islam
Summary: This study conducted a prospective study on patients with flu-like symptoms to explore important symptoms and factors related to mortality in COVID-19 infection. The results may be helpful in early prediction and risk reduction of mortality in patients infected with COVID-19.
JOURNAL OF MEDICAL VIROLOGY
(2021)